Aridity and seasonality of precipitation are characteristics of the highland region in Bolivia. Groundwater becomes an important and safe source of water when surficial bodies are intermittent and affected by natural and anthropogenic contamination. Decades of exploitation of the Challapampa aquifer, combined with lack of information required to understand the groundwater circulation, represent a

Chronic lymphocytic leukemia (CLL) patients with differential somatic hypermutation status of the immunoglobulin heavy variable genes, namely mutated or unmutated, display fundamental clinico-biological differences. Considering this, we assessed prognosis separately within mutated (M-CLL) and unmutated (U-CLL) CLL in 3015 patients, hypothesizing that the relative significance of relevant indicator

The role of hormonal factors in the etiology of lymphoid neoplasms remains unclear. Previous studies have yielded conflicting results, have lacked sufficient statistical power to assess many lymphoma subtypes, or have lacked detailed information on relevant exposures. Within the European Prospective Investigation Into Cancer and Nutrition cohort, we analyzed comprehensive data on reproductive fact

In the complex OR environment, perioperative team members need to practice communication and teamwork to ensure safe, high-qualitycare. A lack of collaboration among professionals in the OR during surgery results in inefficiency, increased tension, and suboptimal patient care. The purpose of this study was to determine how nurse anesthetists and OR nurses experienced their work in the OR. We used

The starting point for this inductive study is to determine, through a search of studies, what critical viewpoints in terms of research are delivered, based on experiences, observations and evaluation, concerning the Bologna Process over time? The aim is to present a description using a thematic analysis based on data from 38 papers (2004–2016) that reveal the critical reasoning behind the researc

Background: Studies assessing institutional performance regarding quality of care are frequently performed using single-level statistical analyses investigating differences between provider averages of various quality indicators. However, such analyses are insufficient as they do not consider patients' heterogeneity around those averages. Hence, we apply a multilevel analysis of individual-patient

Aims: To investigate to what extent socioeconomic differences in swimming abilities persist among children in the city of Malmö, Sweden, after a community-level swimming intervention programme in public primary schools. Methods: A compulsory swimming education programme was launched in 2014 in second grade (at age 8) in all public primary schools in Malmö, Sweden. Data for the present study on soc

US-based philanthropies have long contributed to environmental conservation through non-repayable donations, but some are now beginning to embrace novel investment strategies that are profit-orientated. From the vantage points of political economy and geopolitics, this article investigates the potential ramifications of this shift in funding for large-scale marine protected areas (LMPAs), which ha

Nitrogenase is the only enzyme that can cleave the triple bond in N2, making nitrogen avaiable for other organisms. It contains a complicated MoFe7S9C(homocitrate) cluster in its active site. Many computational studies with density-functional theory (DFT) of the nitrogenase enzyme have been presented, but they do not show any consensus-they do not even agree where the first four protons should be

We examined farmers’ costs of providing public goods under the Common Agricultural Policy (CAP) and the expected impacts of the 2015 CAP “greening” reform on regional development and provisioning of public goods. Less than half of CAP spending Before the reform was justifiable in terms of the delivery of specific public goods; and predicted benefits from greening are low. We recommend re-allocatin

One of the major causes of premature failure in asphalt pavements is moisture damage. Asphalt mixtures designed without considering climate impacts may suffer from durability problems caused by movement of water inside the asphalt mixture. Rolling traffic over wet pavement builds up pore pressure in the mixture, which will consequently accelerate deterioration. The objective of the study was to as

Background: Most validations of paediatric glomerular filtration rate (GFR) estimating equations using standardized creatinine (CR) and cystatin C (CYS) assays have comprised relatively small cohorts, which makes accuracy across subgroups of GFR, age, body mass index (BMI) and gender uncertain. To overcome this, a large cohort of children referred for GFR determination has been established from se

Background: Mothers of preterm infants are at greater risk of symptoms of stress and anxiety compared to mothers of term infants. Aims: This study aimed to explore mothers’ experiences after coming home from the hospital with a moderately to late preterm infant. Methods: A qualitative and explorative method was used. Ten mothers who had given birth to a preterm baby with a gestational age between

Pathogenic mutations in DPAGT1 cause a rare type of a congenital disorder of glycosylation termed DPAGT1-CDG or, alternatively, a milder version with only myasthenia known as DPAGT1-CMS. Fourteen disease-causing mutations in 28 patients from 10 families have previously been reported to cause the systemic form, DPAGT1-CDG. We here report on another 11 patients from 8 families and add 10 new mutatio

This paper is about how the Syrian government lost control over its rural and rural-to-urban constituents. From the twin perspective of ethnography and political economy, I show how the same pressures that structured men’s decisions to migrate from the countryside to sell labour power in the city resemble the material foundations for the uprising itself. The dominant narrative of the Syrian uprisi

Jennie Bradbury and Philip Proudfoot reveal how agriculture is at the heart of both strife and heritage in Syria