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Cyclooxygenase-2 inhibitors (coxibs) are characterized by multiple molecular off-target effects and increased coronary artery disease (CAD) risk. Here, we systematically explored common variants of genes representing molecular targets of coxibs for association with CAD. Given a broad spectrum of pleiotropic effects of coxibs, our intention was to narrow potential mechanisms affecting CAD risk as w

In this paper we develop a system for detection of word-related head movements in audiovisu-al recordings of read news. Our materials consist of Swedish television news broadcasts and comprise audiovisual recordings of five news readers (two female, three male). The corpus was manually labelled for head movement, applying a simplistic annotation scheme consisting of a binary decision about absenceIn this paper we develop a system for detection of word-related head movements in audiovisu-al recordings of read news. Our materials consist of Swedish television news broadcasts and comprise audiovisual recordings of five news readers (two female, three male). The corpus was manually labelled for head movement, applying a simplistic annotation scheme consisting of a binary decision about absence

Seen through the growth of progressive diversity policies it may appear that contemporary organizations are sites of equality. But although inclusion is the formally stated aim of many organizations, exclusionary pressures toward LGBT workers still challenge sexual minorities' access to full inclusion. A central concern in this paper is exploring how to understand inclusion in organizational conte

Recension av Jochen Böhler & Robert Gerwarth (red.), The Waffen-SS – A European History.

The innovation systems framework enables a view of innovation as a process involving different actors in different constellations, but it has nonetheless most often been paired with quantitatively oriented studies of patents, licences and spin-offs. In this article, the authors use two cases of technological innovation at an academically organized but user-oriented research facility for experiment

This article chronicles the most recent history of the Deutsches Elektronen-Synchrotron (DESY) located in Hamburg, Germany, with particular emphasis on how this national laboratory founded for accelerator-based particle physics shifted its research program toward multi-disciplinary photon science. Synchrotron radiation became DESY’s central experimental research program through a series of changesThis article chronicles the most recent history of the Deutsches Elektronen-Synchrotron (DESY) located in Hamburg, Germany, with particular emphasis on how this national laboratory founded for accelerator-based particle physics shifted its research program toward multi-disciplinary photon science. Synchrotron radiation became DESY’s central experimental research program through a series of changes

Hematological malignancies are defined by their underlying genetic alterations, many of which are used to diagnose patients to classify them to different risk groups that dictate the therapy given. Recent advances in high-throughput sequencing have highlighted the presence of co-occurring genetic lesions and that they may form distinct genetic clones that evolve throughout disease progression. Acu

The use of fossil resources must be phased out during the next few decades in order to meet the adopted 2° target. The transition to non-fossil feedstocks in the production of chemicals and transportation fuels will make it increasingly important to economise on the biomass carbon since biomass is a limited resource. Carbon dioxide (CO2) can be used as carbon feedstock and thus serve as a valuable

Changes to the contemporary food system, including meals and eating patterns, have occurred quickly. One such change over the past 30 years has been the increase of commercially produced foods aimed at food allergies and intolerances and ‘free from’ dieting. The gluten free diet has recently emerged as a popular diet trend in Western countries, outpacing its origins as a treatment for celiac disea

Cellobiose dehydrogenase (CDH) is a versatile bioelectrocatalyst lately at focus due to its sugar oxidising properties in combination with its inherent ability for direct electron transfer communication with electrodes making it possible to be used in bioanodes in the enzymatic fuel cells (EFCs), self-powered biosensors, and biosupercapacitors. During the last 20 years, many new nanomaterials and

The Amazon rainforest is disproportionately important for global carbon storage and biodiversity. The system couples the atmosphere and land, with moist forest that depends on convection to sustain gross primary productivity and growth. Earth system models that estimate future climate and vegetation show little agreement in Amazon simulations. Here we show that biases in internally generated clima

Purpose The purpose of this study was to illuminate how men under 65 years of age experience their everyday Life one year or more after a radical prostatectomy for localised prostate cancer. Method Interviews with 19 men aged under 65 were performed 12–18 months after their radical prostatectomy. The interviews were analysed using a thematic content analysis. Results The analysis of the interviews

Small wintering passerines adaptively modulate daily body mass acquisition as part of their energy management policy. However, whether birds optimize overnight mass loss or body mass at dawn remains poorly understood. We studied environmental correlates of individual variation in body mass at dusk, overnight mass loss and body mass at dawn in a wild population of Great Tits Parus major wintering i