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Extensive/Multidrug-Resistant Pneumococci Detected in Clinical Respiratory Tract Samples in Southern Sweden Are Closely Related to International Multidrug-Resistant Lineages

Background/Objective: The frequencies of non-susceptibility against common antibiotics among pneumococci vary greatly across the globe. When compared to other European countries antibiotic resistance against penicillin and macrolides has been uncommon in Sweden in recent years. Multidrug resistance (MDR) is, however, of high importance since relevant treatment options are scarce. The purpose of th

Tillgänglighetsproblem orsakade av trappsteg: En fallstudie i flerfamiljshus

Rapporten redogör för en fallstudie om hur tillgänglighetsproblem i flerfamiljshus förorsakade av trappsteg kan lösas på nya och bättre sätt. Fyra hus byggda 1959-1966 valdes ut för att ingå i fallstudien. Tre var typiska för flerfamiljshus i Sverige som saknar hissar. Det fjärde huset hade efterinstallerade hissar. Fallens entrémiljöer utvärderades på en undersökande nivå med tillgänglighetsinven

Ideal types’ strategies related to handling early stages of the COVID-19 pandemic : A thematic analysis of comments from an international survey

People (re)act differently when facing the pandemic. Multiple opinions about COVID-19 and related issues prevail, both in personal meetings and in (social) media. This article aims to illuminate different ideal types and handling strategies in early stages of the pandemic. A thematic Braun and Clark, and Weber inspired analysis of qualitative data from an international web-based survey was carried

Evaluation of Antibiotic-Based Selection Methods for Camelina sativa Stable Transformants

Camelina sativa (Camelina) is an oilseed crop that in recent years has gained importance due to its closeness to the plant model organism Arabidopsis thaliana (Arabidopsis), its low agronomical requirements, and the ability to grow under temperate conditions. To explore all the agronomical and biotechnological possibilities of this crop, it is important to evaluate the usability of the molecular p

Dual SGLT1/SGLT2 inhibitor phlorizin reduces glucose transport in experimental peritoneal dialysis

Introduction: Glucose absorption during peritoneal dialysis (PD) is commonly assumed to occur via paracellular pathways. We recently showed that SGLT2 inhibition did not reduce glucose absorption in experimental PD, but the potential role of glucose transport into cells is still unclear. Here we sought to elucidate the effects of phlorizin, a non-selective competitive inhibitor of sodium glucose c

Prevalence of endometriosis and adenomyosis at transvaginal ultrasound examination in symptomatic women

INTRODUCTION: Prevalence of endometriosis is commonly reported based on surgery findings and varies widely depending on study population and indication for surgery. Symptoms such as dysmenorrhea, pelvic pain, dyspareunia, dysuria, and dyschezia can be associated with endometriosis and adenomyosis. Transvaginal ultrasound examination is proposed to be the first-line diagnostic method, nevertheless

Transient birefringence and dichroism in ZnO studied with fs-time-resolved spectroscopic ellipsometry

The full transient dielectric-function (DF) tensor of ZnO after UV-laser excitation in the spectral range 1.4-3.6 eV is obtained by measuring an m-plane-oriented ZnO thin film with femtosecond (fs)-time-resolved spectroscopic ellipsometry. From the merits of the method, we can distinguish between changes in the real and the imaginary part of the DF as well as changes in birefringence and dichroism

Characterization of the high harmonics source for the VUV ellipsometer at ELI Beamlines

In this paper, the authors present the characterization experiments of a 20 fs vacuum ultraviolet beam from a high harmonic generation source. The beam hits a silicon sample and passes a triple reflection gold polarizer located inside an ultrahigh vacuum chamber. The polarizer's Malus curve was obtained; the total acquisition time for each point of the curve was 30 s. This aims to be the first vac

Progress on laser-driven X-ray sources at ELI Beamlines

Three main paths are being developed within the ELI research program for transforming driving laser pulses into bursts of bright short wavelength radiation: high-order harmonic generation in gases, plasma X-ray sources and sources based on relativistic electron beams accelerated in laser plasma. For each of these research areas, dedicated beamlines are built to provide a unique combination of X-ra

Epsilon-Near-Zero Substrate Engineering for Ultrathin-Film Perfect Absorbers

Efficient suppression of reflection is a key requirement for perfect absorption of light. Recently, it has been shown that reflection can be effectively suppressed utilizing a single ultrathin film deposited on metals or polar materials featuring phonon resonances. The wavelength at which reflection can be fully suppressed is primarily determined by the nature of these substrates and is pinned to

Process modularity, supply chain responsiveness, and moderators : The Médecins Sans Frontières response to the Covid-19 pandemic

The unprecedented scale of the Covid-19 pandemic has been a challenge for health supply chains around the world. Many international humanitarian organizations have had to ensure the continuity of their already complex development programs, while addressing their supply chain disruptions linked to the pandemic. Process modularity has frequently been advocated as a strategy to mitigate such disrupti

Regional differences in treatment and outcome for myeloma patients in Sweden : A population based Swedish myeloma register study

Background: We wanted to evaluate if health care for multiple myeloma (MM) patients is equal in different regions of Sweden. Aim: To study differences in survival for MM depending on health care region and early use of modern treatment. Methods and results: Data from the Swedish Myeloma Register from patients diagnosed between 2008 and 2017 was used. Cohorts were defined by the six healthcare regi

Lund Film Society and Interwar Cultural Propaganda

During the interwar period, there was a surge in cultural diplomacy efforts in Europe. This article investigates the role of cultural diplomacy within the Swedish film society movement, focusing particularly on Lund Film Society’s travels abroad during the 1930s: to Nazi-Germany in 1935 and in 1938 respectively, as well as to the Soviet Union in 1936. Through international exchange, Lund Film Soci

Mechanobiological model for simulation of injured cartilage degradation via proinflammatory cytokines and mechanical

Post-traumatic osteoarthritis (PTOA) is associated with cartilage degradation, ultimately leading to disability and decrease of quality of life. Two key mechanisms have been suggested to occur in PTOA: Tissue inflammation and abnormal biomechanical loading. Both mechanisms have been suggested to result in loss of cartilage proteoglycans, the source of tissue fixed charge density (FCD). In order to

Pseudouridine-modified tRNA fragments repress aberrant protein synthesis and predict leukaemic progression in myelodysplastic syndrome

Transfer RNA-derived fragments (tRFs) are emerging small noncoding RNAs that, although commonly altered in cancer, have poorly defined roles in tumorigenesis1. Here we show that pseudouridylation (Ψ) of a stem cell-enriched tRF subtype2, mini tRFs containing a 5′ terminal oligoguanine (mTOG), selectively inhibits aberrant protein synthesis programmes, thereby promoting engraftment and differentiat

Increased risk for developing gambling disorder under the treatment with pramipexole, ropinirole, and aripiprazole : A nationwide register study in Sweden

Gambling Disorder (GD) has recently been reclassified from an impulse-control disorder to a behavioural addiction and, as in other addictive disorders, the dopaminergic reward system is involved. According to neuroimaging studies, alterations within the striatal dopaminergic signalling can occur in GD. However, the findings to date are controversial and there has been no agreement yet on how the r