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Providing User Security Guarantees in Public Infrastructure Clouds

The infrastructure cloud (IaaS) service model offers improved resource flexibility and availability, where tenants-insulated from the minutiae of hardware maintenance-rent computing resources to deploy and operate complex systems. Large-scale services running on IaaS platforms demonstrate the viability of this model; nevertheless, many organizations operating on sensitive data avoid migrating oper

On improving resistance to Denial of Service and key provisioning scalability of the DTLS handshake

DTLS is a transport layer security protocol designed to provide secure communication over unreliable datagram protocols. Before starting to communicate, a DTLS client and server perform a specific handshake in order to establish a secure session and agree on a common security context. However, the DTLS handshake is affected by two relevant issues. First, the DTLS server is vulnerable to a specific

Bootstrapping trust in software defined networks

Software-Defined Networking (SDN) is a novel architectural model for cloud network infrastructure, improving resource utilization, scalability and administration. SDN deployments increasingly rely on virtual switches executing on commodity operating systems with large code bases, which are prime targets for adversaries attacking the network infrastructure. We describe and implement TruSDN, a frame

Perioperative alcohol cessation intervention for postoperative complications

Background: Risky consumption of alcohol is a global problem. More than 3.3 million deaths annually are associated with risky use of alcohol, and global alcohol consumption continues to increase. People who have high alcohol consumption often require planned and emergency surgical procedures. Risky drinking is associated with increased postoperative complications such as infections, cardiopulmonar

Aerodynamics of manoeuvring flight in brown long-eared bats (Plecotus auritus)

In this study, we explicitly examine the aerodynamics of manoeuvring flight in animals. We studied brown long-eared bats flying in a wind tunnel while performing basic sideways manoeuvres. We used particle image velocimetry in combination with high-speed filming to link aerodynamics and kinematics to understand the mechanistic basis of manoeuvres. We predicted that the bats would primarily use the

Sexual dimorphism in a top predator (Notophthalmus viridescens) drives aquatic prey community assembly

Intraspecific variation can have important consequences for the structure and function of ecological communities, and serves to link community ecology to evolutionary processes. Differences between the sexes are an overwhelmingly common form of intraspecific variation, but its community-level consequences have never been experimentally investigated. Here, we manipulate the sex ratio of a sexually

High-level software requirements and iteration changes : a predictive model

Knowing whether a software feature will be completed in its planned iteration can help with release planning decisions. However, existing research has focused on predictions of only low-level software tasks, like bug fixes. In this paper, we describe a mixed-method empirical study on three large IBM projects. We investigated the types of iteration changes that occur. We show that up to 54% of high

Protected areas act as a buffer against detrimental effects of climate change—Evidence from large-scale, long-term abundance data

Climate change is driving species to shift their distributions toward high altitudes and latitudes, while habitat loss and fragmentation may hamper species ability to follow their climatic envelope. These two drivers of change may act in synergy, with particularly disastrous impacts on biodiversity. Protected areas, PAs, may thus represent crucial buffers against the compounded effects of climate

Toll-like receptor 3 agonist, polyinosinic-polycytidylic acid, upregulates carbonic anhydrase ii in human keratinocytes

Carbonic anhydrases are ubiquitously expressed enzymes that reversibly hydrate carbon dioxide to bicar-bonate and protons. While the main function of carbonic anhydrases is to regulate pH and osmotic balance, their involvement in other physiological processes remains to be explored. This study analysed changes in mRNA and protein levels of carbonic anhydrase II in human primary keratinocytes treat

The approximability of maximum rooted triplets consistency with fan triplets and forbidden triplets

The NP-hard maximum rooted resolved triplets consistency problem (MRTC) takes as input a set [Formula presented] of leaf labels and a set [Formula presented] of resolved triplets over [Formula presented] and asks for a rooted phylogenetic tree that is consistent with the maximum number of elements in [Formula presented]. This article studies the approximability of a generalization of the problem c

Intensive management reduces butterfly diversity over time in urban green spaces

Loss and fragmentation of semi-natural grasslands have had negative consequences for grassland biodiversity, such as butterflies. Urban parks and other urban green spaces have so far largely been overlooked as suitable butterfly habitats, although they could potentially sustain diverse butterfly populations over time. We analysed the temporal change in butterfly species assemblages in urban green

Relations between implementation of new treatments and improved outcomes in patients with non-ST-elevation myocardial infarction during the last 20 years : experiences from SWEDEHEART registry 1995 to 2014

Aims: We assessed the changes in short- and long-term outcomes and their relation to implementation of new evidence-based treatments in all patients with non-ST-elevation myocardial infarction (NSTEMI) in Sweden over 20 years. Methods and results: Cases with NSTEMI (n = 205 693) between 1995 and 2014 were included from the nationwide Swedish Web-System for Enhancement and Development of Evidence-B

Simulation of magnetised microstructure evolution based on a micromagnetics-inspired FE framework : application to magnetic shape memory behaviour

Microstructure evolution in magnetic materials is typically a non-local effect, in the sense that the behaviour at a material point depends on the magnetostatic energy stored within the demagnetisation field in the entire domain. To account for this, we propose a finite element framework in which the internal state variables parameterising the magnetic and crystallographic microstructure are treat

Impact of rye-based evening meals on cognitive functions, mood and cardiometabolic risk factors : A randomized controlled study in healthy middle-aged subjects

Background: Whole grain (WG) intake is associated with reduced risk of obesity, type 2 diabetes and cardiovascular disease, whereas type 2 diabetes increases the risk of cognitive decline and dementia. The purpose of this study was to investigate the effects of short-term intervention with WG rye on cognitive functions, mood and cardiometabolic risk markers in middle-aged test subjects. Method: Ry

Neuroarchitecture of the dung beetle central complex

Despite their tiny brains, insects show impressive abilities when navigating over short distances during path integration or during migration over thousands of kilometers across entire continents. Celestial compass cues often play an important role as references during navigation. In contrast to many other insects, South African dung beetles rely exclusively on celestial cues for visual reference

PA28αβ overexpression enhances learning and memory of female mice without inducing 20S proteasome activity

BACKGROUND: The proteasome system plays an important role in synaptic plasticity. Induction and maintenance of long term potentiation is directly dependent on selective targeting of proteins for proteasomal degradation. The 20S proteasome activator PA28αβ activates hydrolysis of small nonubiquitinated peptides and possesses protective functions upon oxidative stress and proteinopathy. The effect o

Differential coding of perception in the world's languages

Is there a universal hierarchy of the senses, such that some senses (e.g., vision) are more accessible to consciousness and linguistic description than others (e.g., smell)? The long-standing presumption in Western thought has been that vision and audition are more objective than the other senses, serving as the basis of knowledge and understanding, whereas touch, taste, and smell are crude and of

Inhibitors in haemophilia A and B : Management of bleeds, inhibitor eradication, and strategies for difficult-to-treat patients

The standard therapy for patients with haemophilia is prophylactic treatment with replacement factor VIII (FVIII) or factor IX (FIX). Patients who develop inhibitors against FVIII/FIX face an increased risk of bleeding, and the likelihood of early development of progressive arthropathy, alongside higher treatment-related costs. Bypassing agents can be used to prevent and control bleeding, as well

Carvone Contact Allergy in Southern Sweden : A 21-year Retrospective Study

Carvone (l-carvone), a mint flavour in spearmint oil, is considered a mild skin sensitizer. Carvone-sensitization may be linked to oral/perioral signs and oral lichen planus, but studies are sparse. The prevalence of patch test reactions to carvone and relevant findings from the positive group were investigated. Records for patch-tested patients at the Malmö clinic, for the period 1996 to 2016, we