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Thermal conductivity of ScxAl1−xN and YxAl1−xN alloys

Owing to their very large piezoelectric coefficients and spontaneous polarizations, (Sc,Y) x Al1−xN alloys have emerged as a new class of III-nitride semiconductor materials with great potential for high-frequency electronic and acoustic devices. The thermal conductivity of constituent materials is a key parameter for design, optimization, and thermal management of such devices. In this study, tra

Umbilical cord pH, blood gases, and lactate at birth : normal values, interpretation, and clinical utility

Normal birth is a eustress reaction, a beneficial hedonic stress with extremely high catecholamines that protects us from intrauterine hypoxia and assists in the rapid shift to extrauterine life. Occasionally the cellular O2 requirement becomes critical and an O2 deficit in blood (hypoxemia) may evolve to a tissue deficit (hypoxia) and finally a risk of organ damage (asphyxia). An increase in H+ c

Direct Reprogramming of Mouse and Human Fibroblasts into Conventional Dendritic Cells Type 1

Cell fate reprogramming of adult cells towards pluripotency or unrelated somatic cell-types has been explored in the context of regenerative medicine. Dendritic cells (DCs) are professional antigen presenting cells (APCs) specialized in the recognition, processing and presentation of antigens to T-cells, inducing adaptive immunity. In particular, the mouse conventional DCs type 1 (cDC1) subset or

Restoring the immunogenicity of cancer cells with dendritic cell reprogramming

An important hallmark of cancer is the ability to evade the immune system. Genetic mutations may result in the accumulation of tumor antigens, however, downregulation of antigen presentation in tumor cells results in decreased immunogenicity and immune surveillance evasion. Recently, we demonstrated that enforced expression of PU.1, IRF8 and BATF3 (PIB) imposes a conventional dendritic cell type 1

Open Letters and Climate Communication : The Professional Roles and Identities of Researchers in Times of Crisis

Open letters are seen as a politicized form of climate communication, and the professional roles of researchers who engage in these communicative events are thereby cast into question. Based on semi-structured interviews with initiators to open letters, this article argues that while communication can be seen as constitutive and influencing new and emergent professional identities, there are also

Territoriology and the study of public place

In this chapter, we present why and how a territorial perspective on urban design and public space can be fruitful. We start by introducing the notion of territoriology, and then go on to present a brief history of how territoriality traditionally has been discussed in relation to urban design, ending with a few examples of some more recent territoriological studies. We then give a few examples of

Human, What Must I Tell You?

Artificial intelligence (AI)-assisted code generation is everywhere these days. Undoubtedly, AI will help near-future developers substantially by providing code suggestions and automation. In this application, explainability will be a key quality attribute.

A Research Agenda for Sustainable Cities and Communities

Global in its outlook, this Research Agenda systematically reviews and critiques existing research on sustainable cities, calling for greater engagement with a diversity of perspectives. It interrogates foundational assumptions in the field and offers reframed perspectives on sustainability. Chapters also explore diverse approaches, actors and domains, locating emerging dynamics and new directions

DDPC : Automated Data-Driven Power-Performance Controller Design on-the-fly for Latency-sensitive Web Services

Traditional power reduction techniques such as DVFS or RAPL are challenging to use with web services because they significantly affect the services' latency and throughput. Previous work suggested the use of controllers based on control theory or machine learning to reduce performance degradation under constrained power. However, generating these controllers is challenging as every web service app

GATA2 at the mitosis-to-G1 transition is critical for definitive hematopoiesis

In mitosis, transcription factors (TFs) and RNA polymerase disperse across the cytoplasm leading to transcriptional silencing, but some TFs are retained on condensed chromatin and mark genomic sites, a mechanism termed mitotic bookmarking. In pluripotent and differentiated cells this mechanism is important for pluripotency maintenance, cell reprogramming and lineage inheritance. However, the role

The ST22 chronology for the Skytrain Ice Rise ice core - Part 2 : An age model to the last interglacial and disturbed deep stratigraphy

We present an age model for the 651g€¯m deep ice core from Skytrain Ice Rise, situated inland of the Ronne Ice Shelf, Antarctica. The top 2000 years have previously been dated using age markers interpolated through annual layer counting. Below this, we align the Skytrain core to the AICC2012 age model using tie points in the ice and air phase, and we apply the Paleochrono program to obtain the bes

Overview : The Baltic Earth Assessment Reports (BEAR)

Baltic Earth is an independent research network of scientists from all Baltic Sea countries that promotes regional Earth system research. Within the framework of this network, the Baltic Earth Assessment Reports (BEARs) were produced in the period 2019-2022. These are a collection of 10 review articles summarising current knowledge on the environmental and climatic state of the Earth system in the

Long-term changes of nitrogen leaching and the contributions of terrestrial nutrient sources to lake eutrophication dynamics on the Yangtze Plain of China

Over the past half-century, drastically increased chemical fertilizers have entered agricultural ecosystems to promote crop production on the Yangtze Plain, potentially enhancing agricultural nutrient sources for eutrophication in freshwater ecosystems. However, long-term trends of nitrogen dynamics in terrestrial ecosystems and their impacts on eutrophication changes in this region remain poorly

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Recent electoral victories by left-leaning leaders and parties mark another turn in the oscillations of Latin American politics, but they also signal enduring changes. The electoral success of the left is a sign of both the durability of electoral democracy and the persistence of social pres-sures in highly unequal societies. In this article, we discuss how the electoral fates and governing strate

Uncovering the cytotoxic effects of air pollution with multi-modal imaging of in vitro respiratory models

Annually, an estimated seven million deaths are linked to exposure to airborne pollutants. Despite extensive epidemiological evidence supporting clear associations between poor air quality and a range of short- and long-term health effects, there are considerable gaps in our understanding of the specific mechanisms by which pollutant exposure induces adverse biological responses at the cellular an

The chemical characterization of halo substructure in the Milky Way based on APOGEE

Galactic haloes in a Λ-CDM universe are predicted to host today a swarm of debris resulting from cannibalized dwarf galaxies. The chemodynamical information recorded in their stellar populations helps elucidate their nature, constraining the assembly history of the Galaxy. Using data from APOGEE and Gaia, we examine the chemical properties of various halo substructures, considering elements that s

A nutritional biomarker score of the Mediterranean diet and incident type 2 diabetes : Integrated analysis of data from the MedLey randomised controlled trial and the EPIC-InterAct case-cohort study

Background AU Self-reported: Pleaseconfirmthatallheadinglevelsarerepresentedcorrectly adherence to the Mediterranean diet has been: modestly inversely associated with incidence of type 2 diabetes (T2D) in cohort studies. There is uncertainty about the validity and magnitude of this association due to subjective reporting of diet. The association has not been evaluated using an objectively measured

CONTRASTS OF REGISTER UNDERLIE THE PERCEPTION OF MUSICAL HUMOR

IN THE PSYCHOLOGICAL LITERATURE ON MUSICAL humor, the emphasis on laughter-inducing music has naturally led researchers to focus on quite uncommon devices, such as stylistic deviations or formal incongruities that strongly violate listeners' expectations, as the privileged basis for musical humor. But musical humor extends well beyond laughter-inducing music. It is also a kind of semantic content

Precise dd excitations and commensurate intersite Coulomb interactions in the dissimilar cuprates YBa2Cu3 O7-y and La2-xSrxCu O4

Using high-resolution extreme ultraviolet resonant inelastic x-ray scattering (EUVRIXS) spectroscopy at the Cu M-edge, we observed doping dependent spectral shifts of interorbital (dd) excitations of YBa2Cu3O7-y and La2-xSrxCuO4. With increasing the hole doping level from undoped to optimally doped superconducting compositions, the leading edge of dd excitations is found to shift towards lower ene

A hypothesis for robust polarization vision : an example from the Australian imperial blue butterfly, Jalmenus evagoras

The Australian lycaenid butterfly Jalmenus evagoras has iridescent wings that are sexually dimorphic, spectrally and in their degree of polarization, suggesting that these properties are likely to be important in mate recognition. We first describe the results of a field experiment showing that free-flying individuals of J. evagoras discriminate between visual stimuli that vary in polarization con