Methods were developed for the synthesis of three different types of macrocyclic carbohydrate/amino acid hybrid molecules. In the synthesis of the first type of macrocycles, a glucosamine derivative was oxidized at C6 and the obtained sugar amino acid was coupled to tripeptides. The resulting hybrids were transformed into dimers and cyclized in a macrolactamization step to obtain C2-symmetric macr

Brief description and interpretation of the eighteenth-century altarpiece by Johan Ullberg in the church of Dalby.

Popular Abstract in Swedish Alla levande organismer måste kunna anpassa sig till förändringar i sin omgivning, såsom kyla, värme eller torka. Vid sådana förändringar tar enskilda celler emot signaler ifrån sin omgivning via särskilda s.k. receptorproteiner på cellytan. Receptorproteinerna skickar signalerna vidare in i cellen, där de kan ge upphov till en kedja av processer, vilka slutligen leder Phosphoinositides (PIs) play major roles in cell signal transduction. Although it is clear that PIs are important components also in plant signalling, little is known about their roles in plant cells, compared to animal cells. This thesis describes work on two PI-dependent enzymes involved in plant intracellular signalling, phosphoinositide-specific phospholipase C (PI-PLC) and 3-phosphoinositide

Abstract not available

The monotone rearrrangement algorithm was introduced by Hardy, Littlewood and Po ́lya as a sorting device for functions. As- suming that x is a monotone function and that an estimate xn of x is given, consider the monotone rearrangement xˆn of xn. This new estimator is shown to be uniformly consistent. Under suitable as- sumptions, pointwise limit distribution results for xˆn are obtained. The fra

This paper explores the linguistic encoding of placement and removal events in Jahai (Austroasiatic, Malay Peninsula) on the basis of descriptions from a video elicitation task. It outlines the structural characteristics of the descriptions and isolates semantically a set of situation types that find expression in lexical opposites: (1) putting/taking, (2) inserting/extracting, (3) dressing/undres

Popular Abstract in Swedish Att balansera. Cancer från ett primärvårdsperspektiv. Diagnostik, posttraumatisk stress och vård vid livets slut Denna avhandling belyser cancer från en utgångspunkt som kanske inte handlar om vad man först kommer att tänka på när man hör ordet cancerforskning. Det handlar inte om att “lösa cancerns gåta” eller att hitta nya metoder för behandling eller diagnos. UtgångThis thesis explores cancer from a primary care perspective covering three areas: diagnosis, posttraumatic stress disorder (PTSD), and end-of-life care. We analyzed patient records of every child diagnosed with a malignancy in a defined area. During 12 years 68 children were diagnosed (incidence 14/100,000). For 68% the diagnosis was initiated in primary care. There were 25 children with leukemia