Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon co

Statement of Purpose: Chronic lung diseases are one of the major health problems that cause death and disability. Approximately 65 million people suffer from chronic lung diseases, and the number of patients is predicted to increase worldwide 1 . Lung transplantation is the only available treatment option for patients at end-stage disease. However, there is a chronic shortage of donor organs, re

Charge balance functions reflect the evolution of charged pair correlations throughout the stagesof pair production, dynamical diffusion, and hadronization in heavy-ion collisions. Microscopic mod-eling of these correlations in the full collision volume shows that the balance functions are sensitiveto the diffusivity of light quarks when studied as functions of relative azimuthal angle. By restric

Mechanical stretch under both physiological (breathing) and pathophysiological (ventilator-induced) conditions is known to significantly impact all cellular compartments in the lung, thereby playing a pivotal role in lung growth, regeneration and disease development. In order to evaluate the impact of mechanical forces on the cellular level, in vitro models using lung cells on stretchable membrane

We derive short-distance constraints for the hadronic light-by-light contribution (HLbL) to the anomalous magnetic moment of the muon in the kinematic region where the three virtual momenta are all large. We include the external soft photon via an external field leading to a well-defined Operator Product Expansion. We establish that the perturbative quark loop gives the leading contribution in a w

The internal microstructure of injection-molded dogbone specimens of talc-filled isotactic polypropylene has been investigated using a home laboratory scanning wide-angle X-ray scattering setup, yielding two-dimensional maps of molecular orientation and ordering for cross-sections parallel and perpendicular to the flow direction with unprecedented details. In addition to demonstrating a high degre

An improved solution of the non-linear and ill-posed inverse problem of electro-cardiography is presented. The hearts activity is modeled by three di®erent equivalent cardiac sources: 1 moving dipole, 2 and 5 fixed location rotating dipoles. For this purpose a three dimensional volume conductor model of the human body is constructed based on a classical anatomic atlas. This is excited by each one

The introduction of high efficiency and multifunctional equipment for road survey increase not only the quality but also the possibility of integration of different source of data to increase the value of the information. The present research work, starting from a common data source, the Automatic Road Analyzer (ARAN) of the University of Catania, shown as data surveyed with ARAN can be used to de

We construct a QCD-based model where soft gluon rescattering between final state partons in deep inelastic scattering leads to events with large rapidity gaps and a leading proton. The model successfully describes the precise HERA data on the diffractive deep inelastic structure function in the whole available kinematical range.

The basic structure of classical density functional theory (DFT) is reviewed from a rather general perspective. The treatment is then specialized to ionic solutions, describing the various possible extensions beyond the Poisson–Boltzmann level, that DFT offers, such as excluded volume effects, non-electrostatic interactions, connectivity (polymers) and ion correlations. The last effects are discus