Baseline trabecular bone and its relation to incident radiographic knee osteoarthritis and increase in joint space narrowing score : directional fractal signature analysis in the MOST study
Purpose To explore the association of baseline trabecular bone structure with incident tibiofemoral (TF) osteoarthritis (OA) and with increase in joint space narrowing (JSN) score. Methods The Multicenter Osteoarthritis Study (MOST) includes subjects with or at risk for knee OA. Knee radiographs were scored for Kellgren–Lawrence (KL) grade and JSN at baseline, 30, 60 and 84 months. Knees (KL ≤ 1)