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Clear-cell renal cell carcinoma (RCC) is, in most cases, caused by loss of function of the tumor suppressor gene von Hippel-Lindau, resulting in constitutive activation of hypoxia-inducible factor (HIF)-1 alpha and expression of hypoxia-induced genes in normoxic conditions. Clear-cell RCC cells are characterized histologically by accumulation of cholesterol, mainly in its ester form. The origin of

Studies of climatic change and adaptation to climate change can include a wide range of methodologies and approaches. As one of such approaches, we here present meteorological measurement data from a site in the Demokeya experimental forest outside El Obeid in North Kordofan State of Sudan. We hope this descriptive note can inform about the available meteorological data, as well as to promote and

X-ray photoelectron spectroscopy and density functional theory calculations are used to investigate NO adsorption at low (100 K) and room temperature (RT) over preoxidized Ag(111). At 100 K, the data indicates presence of NO and N2O2, with little or no nitrite/nitrate formation. This is consistent with the calculated surface core level shifts and the pronounced barrier for nitrite formation. At RT

Popular Abstract in Swedish Vid en knäprotesoperation ersätts ledytorna i knäet med en protes gjord av metall och plast. Den vanligaste orsaken till denna operation är artros(ledsvikt. Antalet knäprotesoperationer ökar stadigt och 2009 utfördes 12,700 förstagångsoperationer i Sverige. Resultaten är överlag goda men en allvarlig komplikation som drabbar mellan 1 och 2% av patienterna är bakterieinfThe Swedish Knee Arthroplasty Register (SKAR) was used to identify 478 cases that underwent a first-time revision with exchange or removal of the prosthesis due to infection during the years 1986–2000. 30% of the infections were diagnosed within 3 months from primary operation and two-thirds were diagnosed within 2 years. These cases frequently had a history of wound complication after the primar

To study the association between lifestyle and biological risk markers measured at one occasion, morbidity and mortality from cardiovascular disease (CVD) and cancer, and morbidity from diabetes approximately 26 years later.

Description of cds of ostensible psi phenomena

Saccharomyces yeasts degrade sugars to two-carbon components, in particular ethanol, even in the presence of excess oxygen. This characteristic is called the Crabtree effect and is the background for the 'make-accumulate-consume' life strategy, which in natural habitats helps Saccharomyces yeasts to out-compete other microorganisms. A global promoter rewiring in the Saccharomyces cerevisiae lineag

Popular Abstract in Swedish Vår hud och våra slemhinnor är ständigt koloniserade med bakterier som lever i fredligt samspel med vår organism. Dessa bakterier tillhör vår normalflora och kan indelas i kommensaler respektive opportunistiska bakterier. Kommensalerna gagnar värden på olika sätt och orsakar inte sjukdom, till skillnad från opportunisterna som under vissa betingelser kan orsaka infektioAbstractBacteria in most environments encase themselves in a hydrated matrix of polysaccharide and protein, forming organized communities called biofilms. In the biofilm bacteria are protected against hostile environments. Biofilms are important clinically because of their persistence despite host defence and their recalcitrance to antimicrobials. This thesis presents three main findings: (i) biof

This paper describes a method of finding thin, elongated structures in images and volumes. We use shortest paths to minimize very general functionals of higher-order curve properties, such as curvature and torsion. Our globally optimal method uses line graphs and its runtime is polynomial in the size of the discretization, often in the order of seconds on a single computer. To our knowledge, we ar

The primary topic of this thesis is a class of tempo-spatial models which are rather flexible in a distributional sense. They prove quite successful in modeling (temporal) dependence structures and go beyond the limitation of Gaussian models, thus allowing for heavy tails and skewness. By generalizing the construction of the above class of models, it is possible to ‘control’ some random geometric

In contrast to acute lymphoblastic leukemia in children, adult cases of this disease are associated with a very poor prognosis. In order to ascertain whether the frequencies and patterns of submicroscopic changes, identifiable with single nucleotide polymorphism array analysis, differ between childhood and adult acute lymphoblastic leukemia, we performed single nucleotide polymorphism array analys

Review of a book on art and occultism

Herbivory is an important part of most ecosystems and affects the ecosystems' carbon balance both directly and indirectly. Little is known about herbivory and its impact on the carbon balance in high arctic mire ecosystems. We hypothesized that trampling and grazing by large herbivores influences the vegetation density and composition and thereby also the carbon balance. In 2010, we established fe

Multi taper spectrogram decomposition of the time-lag kernel of a time-frequency distribution might result in computationally efficient calculations if the number of multi tapers to be considered in the spectrogram are small. In this paper, penalty functions are designed and used in the computation of multi tapers corresponding to the Wigner distribution time-lag kernel. The resulting multi taper

A new program of Compton scattering on deuterium is under way at the tagged-photon facility at MAX-Lab in Lund, Sweden. We will measure differential cross sections between 60A degrees and 150A degrees over the photon energy range 60-115 MeV in 5 MeV steps, with the ultimate goal of obtaining new precision information on the electric and magnetic polarizabilities of the neutron.

Population fluctuations and synchrony influence population persistence; species with larger fluctuations and more synchronised population fluctuations face higher extinction risks. Here, we analyse the effect of diet specialisation, mobility, length of the flight period, and distance to the northern edge of the species' distribution in relation to between-year population fluctuations and synchrony