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The physical properties of polycrystalline materials depend on their microstructure, which is the nano- to centimeter scale arrangement of phases and defects in their interior. Such microstructure depends on the shape, crystallographic phase and orientation, and interfacing of the grains constituting the material. This article presents a new non-destructive 3D technique to study centimeter-sized b

Endohedral metallofullerenes, formed by encaging Gd inside fullerenes like C80, can exhibit enhanced proton relaxitivities compared with other Gd-chelates, making them the promising contrast agents for magnetic resonance imaging (MRI). However, the underlying key energy scales of Gd x Sc3-x N@C80 (x = 1-3) remain unclear. Here, we carry out resonant inelastic X-ray scattering (RIXS) experiments on

High chromium white cast irons (HCCI) with high hardness and abrasiveness owing to a particular combination of hard primary and eutectic carbides were used as workpiece materials for longitudinal turning with binderless cBN (bcBN) and high cBN (hcBN) tools. The materials with low and high Si content were used in as-cast and quenched states. Binderless cBN is prone to cratering and flank wear, whil

The AGATA (Advanced GAmma Tracking Array) tracking detector is being designed to far surpass the performance of the previous generation, Compton-suppressed arrays. In this paper, a characterization of AGATA is provided based on data from the second GSI campaign. Emphasis is placed on the proper corrections required to extract the absolute photopeak efficiency and peak-to-total ratio. The performan

This study explores the impact academic teachers’ writing of a teaching portfolio can have on their professional learning. Through an open-ended questionnaire, 26 academics from three faculties reported on insights, effects on teaching practice, and effects on collegial exchange that the portfolio writing entailed. We discuss how the experienced impact relates to the three competence levels excell

Background: Inflammation related molecules such as tumor necrosis factor-α (TNF-α), interleukin 6 (IL-6), and cardiotrophin-1 (CT-1) are highly expressed in obese individuals and could partly explain some comorbidities associated to obesity. In obese children, lifestyle interventions are able to lower inflammation and reduce cardiovascular risk factors associated with obesity. The aim of the prese

Evidence is presented for a new pathway participating in anterior neural development. It was found that IGF binding protein 5 (IGFBP-5), as well as three IGFs expressed in early embryos, promoted anterior development by increasing the head region at the expense of the trunk in mRNA-injected Xenopus embryos. A secreted dominant-negative type I IGF receptor (DN-IGFR) had the opposite effect. IGF mRN

Symmetrical and asymmetrical fluorinated phenyltriazolyl-thiodigalactoside derivatives have been synthesized and evaluated as inhibitors of galectin-1 and galectin-3. Systematic tuning of the phenyltriazolyl-thiodigalactosides' fluoro-interactions with galectin-3 led to the discovery of inhibitors with exceptional affinities (Kd down to 1-2 nM) in symmetrically substituted thiodigalactosides as we

To determine the spectrum of secreted proteins that are present in the extracellular space of early Xenopus embryos, a direct secretion screen was performed. Surprisingly, 24% of previously identified bona fide secretory proteins corresponded to four secreted Wnt antagonists of the same family: frzb-1, sizzled, sfrp-2 and crescent. sfrp-2 and crescent are novel components of the growing cocktail o

We analysed the role of the prechordal plate in forebrain development of chick embryos in vivo. After transplantation to uncommitted ectoderm a prechordal plate induces an ectopic, dorsoventrally patterned, forebrain-like vesicle. Grafting laterally under the anterior neural plate causes ventralization of the lateral side of the forebrain, as indicated by a second expression domain of the homeobox

While some mosquitoes are known to have an innate penchant for human hosts, new research details that they can learn, what they can learn and how they can learn. While some mosquitoes are known to have an innate penchant for human hosts, new research details that they can learn, what they can learn and how they can learn.

Right-wing, xenophobic and racist parties have enjoyed immense successes in Europe in recent decades. In Sweden, the third-largest party in Parliament is the Sweden Democrats (SD), with 13% in the 2014 general election. Sympathy for the SD among foreign-born Swedish citizens, both women and men, is far lower than among Sweden-born men, but an increasing number of Swedish citizens with migrant back

Rope Hadronization is a model extending the Lund string hadronization model to describe environments with many overlapping strings, such as high multiplicity pp collisions or AA collisions. Including effects of Rope Hadronization drastically improves description of strange/non-strange hadron ratios as function of event multiplicity in all systems from e+e- to AA. Implementation of Rope Hadronizati

A CsF-mediated method has been developed for the N-arylation of amino sugars that affords good to excellent yields of arylated products under mild conditions involving the in situ generation of arynes. The reaction conditions tolerate a variety of common carbohydrate protecting groups and also performs exceptionally well on unprotected amino sugar derivatives. The reactions are scalable in moderat