Search results

Filter

Filetype

Your search for "*" yielded 552396 hits

Wavelet-based method for noise characterization and rejection in high-performance liquid chromatography coupled to mass spectrometry

We present a new method for rejecting noise from HPLC-MS data sets. The algorithm reveals peptides at low concentrations by minimizing both the chemical and the random noise. The goal is reached through a systematic approach to characterize and remove the background. The data are represented as two-dimensional maps, in order to optimally exploit the complementary dimensions of separation of the pe

The Aldose Reductase Inhibitor Fidarestat Suppresses Ischemia-Reperfusion-Induced Inflammatory Response in Rat Retina.

Recent studies suggest that increased aldose reductase (AR) activity plays an important role in ischemia-reperfusion injury in the retina. The mechanisms are not completely understood, but may be linked to inflammation. In the present study, we investigated whether the AR inhibitor fidarestat suppressed the retinal inflammatory response induced by ischemia-reperfusion in a rat model. The inflammat

Fixation of microsporidian spores for electron microscopy

Fresh and frozen spores of the microsporidia Nosema apis and Nosema bombi were fixed using various fixatives at different times and temperatures. Paraformaldehyde and technical formaldehyde gave results comparable to or better than glutaraldehyde. Increased fixation temperature improved the fixation of spores from terrestrial hosts. Freezing did not destroy the cytology or the spore.

Natural convection heat transfer from a thermal heat source located in a vertical plate fin

A steady state conjugate conduction-convection investigation is performed on vertical plate fin in which a small heat source is located. Heat from the fin surface is transferred to the surroundings by laminar natural convection. The governing equations for the problem are the heat conduction equation for the fin and the boundary layer equations, which are continuity, momentum and energy equations,

On the history of supportive therapy

A short history of supportive therapy is delineated by the quadruple division in prehistory, definition, establishment and the phase of integration. Glimpses of the history of the development of the supportive concept are given. It is pointed out that the concept of supportive therapy is stemming from the awkward dichotomy from the ego-psychological paradigm in the psychoanalytic tradition: insigh

Discrepancy in mitochondrial and nuclear polymorphism in meadow vipers (Vipera ursinii) questions the unambiguous use of mtDNA in conservation studies

The sequence diversity of the entire mitochondrial control region (CR) of three meadow viper (Vipera ursinii) populations was analysed and compared to previously documented nuclear genetic variability at the major histocompatibility complex (MHC) Class I loci. One of the populations, a small and inbred Hungarian population, exhibited no MHC polymorphism, whereas the two other, sampled from large v

The effects of growth hormone (GH) deficiency and GH replacement on cognitive performance in adults: A meta-analysis of the current literature

Objective: There is growing evidence in the neuropsychological literature that growth hormone (GH) deficiency is associated with cognitive impairment. There is also evidence that this impairment may be ameliorated with GH replacement therapy. The current study assessed the nature and severity of cognitive impairment associated with growth hormone deficiency, as well as effect of GH replacement on

Pictures and spoken descriptions elicit similar eye movements during mental imagery, both in light and in complete darkness

This study provides evidence that eye movements reflect the positions of objects while participants listen to a spoken description, retell a previously heard spoken description, and describe a previously seen picture. This effect is equally strong in retelling from memory, irrespective of whether the original elicitation was spoken or visual. In addition, this effect occurs both while watching a b

Costly steroids: egg testosterone modulates nestling metabolic rate in the zebra finch

The transfer of non-genetic resources from mother to the offspring often has considerable consequences for offspring performance. In birds, maternally derived hormones are known to influence a variety of morphological, physiological and behavioural traits in the chick. So far, the range of these hormonal effects involves benefits in terms of enhanced growth and competitive ability as well as costs

Changes in structural attributes of plant communities along disturbance gradients in a dry deciduous forest of Western Ghats, India

Changes in tree and understory plant diversity and community composition in two sites at different disturbance levels were studied on the Anaikatty hills, Western Ghats. Systematic sampling using small scale permanent quadrates (50 x 20 m for trees, 5 x 5 m for shrubs/saplings, 1 x 1 m for herbs/seedlings) enumerated 3,376 individuals of trees (106 species), 8,599 of individuals shrubs (122 specie

Prompt Proton Decay in the Vicinity of 56Ni

A new decay mode, the so called prompt proton decay, was discovered in 1998. It has since proven to be an important decay mechanism for several neutron deficient nuclei in the A similar to 60 region. To measure with high accuracy the energies and angular distributions of these protons, a state-of-the-art charged particle detector - LuWuSiA - was developed. It was first utilized during a fusion-eva

Artificial selection for increased comb size and its effects on other sexual characters and viability in gallus-domesticus (the domestic chicken)

The expression of secondary ornaments is often positively correlated with the bearer's condition. So far no study has reported on consequences of directional selection on male sexual ornaments in birds, i.e. it is unknown to what extent male sexual traits are genetically correlated and whether selection for secondary ornaments affects viability. In this study we estimate phenotypic and genotypic p

Evolution of free, complexed, and total serum prostate-specific antigen and their ratios during 1 year of follow-up of men with febrile urinary tract infection

Objectives. To determine the serum values of free, complexed, and total prostate-specific antigen (PSA) and their ratios in men with febrile urinary tract infection (UTI) during 1 year of follow-up. Methods. A total of 54 men were prospectively enrolled in the study, and serum samples were obtained at the acute stage of the UTI and after 1, 3, 6, and 12 months. Results. Most men had a rise (median

Nanoelectrochemical transducers for (bio-) chemical sensor applications fabricated by nanoimprint lithography

Nanometer-structured transducers for commercial use in pharmaceutical, medical or (bio-) chemical analysis have so far been hardly accessible since they could not be produced by parallel lithography techniques at reasonable costs. We introduce here a method on. how to fabricate nanometer-structured interdigitated array electrodes including interconnections and bond pads in the micrometer range in