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This study offers a method for empirically testing theories operationalized in the form of multivariate statistical models. An innovation of the method is that it distinguishes testing into three separate forms, “effect testing,” “prediction testing,” and “theory testing,”where statistical significance plays a separate role in each one. In another innovation, the researcher specifies not only his
Stable positive linear time-invariant autonomous systems admit diagonal quadratic Lyapunov functions. Such a property is known to be useful in distributed and scalable control of positive systems. In this paper, it is established that the same holds for exponentially stable positive discrete-time and continuous-time linear time-varying systems.
We consider a class of structured covariance completion problems which aim to complete partially known sample statistics in a way that is consistent with the underlying linear dynamics. The statistics of stochastic inputs are unknown and sought to explain the given correlations. Such inverse problems admit many solutions for the forcing correlations, but can be interpreted as an optimal low-rank a
Can local communities on the margins of society be charged with the responsibility of maintaining their own social order? What type of law (if any) can bring social order to these communities? Using semi-structured interviews with social workers, police officers, lawyers and other professionals familiar with the Tottenham riots, this chapter offers an inside view into what community means in a runCan local communities on the margins of society be charged with the responsibility of maintaining their own social order? What type of law (if any) can bring social order to these communities? Using semi-structured interviews with social workers, police officers, lawyers and other professionals familiar with the Tottenham riots, this chapter offers an inside view into what community means in a run
The transient-state kinetic consequences of the coupling of a single-enzyme reaction to other metabolic reactions have been examined in generalized terms. Analytical data are presented which specify under what conditions such coupling may lead to an oscillatory transient rate behaviour of a reaction system involving an enzyme operating by a Michaelian mechanism. The results indicate that the prese
A kinetic model for photosynthetic carbohydrate formation in the chloroplast of C3 plants is presented which includes consideration of the interaction of the phosphate translocator of the chloroplast envelope with external reactants such as 3-phosphoglycerate, dihydroxyacetone phosphate, and glyceraldehyde 3-phosphate in addition to inorganic (ortho)phosphate. The model is shown to account satisfa
An extension of the available kinetic theory for reactions in the transient state is presented which establishes that single‐enzyme reactions may exhibit damped oscillations under the conditions of standard kinetic experiments performed by stopped‐flow techniques. Such oscillations may occur for reasonable magnitudes of rate constants in the enzymic reaction mechanism and at physiological concentr
Control analyses and kinetic model studies have been performed in order to obtain quantitative information on the regulatory significance of 12 experimentally well‐documented inhibitory interactions of Calvin cycle intermediates with the four non‐equilibrium cycle enzymes. Evidence is presented to show that none of these interactions contributes significantly to the cycle flux control over the ran
