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Diffuse traumatic brain injury in mice is associated with a transient mismatch of cerebral blood flow and energy metabolism

Axonal injuries commonly contribute to poor functional outcomes following traumatic brain injury (TBI). To assess cerebral blood flow (CBF) and energy metabolic disturbances in a TBI model of widespread axonal injury, we exposed 105 adult mice to the central (midline) fluid percussion injury (cFPI) diffuse TBI model, or sham injury, and used 9.4 T magnetic resonance (MR) arterial spin labeling (AS

Attosecond spectroscopy reveals spontaneous symmetry breaking in molecular photoionization

Spontaneous symmetry breaking, driven by nonadiabatic electron-nuclear coupling, can lead to geometric com plexity in molecules and solids. While structural distortion from symmetry breaking occurs in femtoseconds, the timescale to lift electronic state degeneracy has remained elusive. We use the vibrationally resolved attosecond chronoscope to capture the electronic symmetry breaking induced by t

Entanglement in photoionisation reveals the effect of ionic coupling in attosecond time delays

Attosecond photoelectron interferometry, based on the measurement of photoelectron spectra generated by a two-colour field, provides access to the photoionisation dynamics of quantum systems. In general, due to the entanglement between the wave function of the emitted photoelectron and that of the parent ion, the dynamics driven by the infra-red field in the photoion can affect the properties of t

Enhancing forward osmosis : Practical aspects and development of binary draw solutions

Forward osmosis (FO) and membrane distillation (MD) have emerged as promising processes for seawater desalination. One of the key factors influencing the FO process is the selection of a suitable draw solution (DS), which should exhibit high osmotic pressure and easy regeneration through a secondary process such as MD. Thermo-responsive polymers having ethylene oxide (EO) and propylene oxide (PO)

Cholesterol in mRNA-Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG-1

Messenger RNA (mRNA) vaccines based on lipid nanoparticles (LNPs) are stabilized with cholesterol, which is thought to be a critical LNP component because it is essential for membrane integrity and endosomal escape. Here, it is shown that cholesterol in LNPs can be replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C-type lectin receptor agonist monomycoloyl glycerol (MMG

Preferences, goals and implications for paternalism

This paper proposes a conceptual model of decision-making tying specific preferences to broader individual goals. Specifically, we consider terminal goals, representing fundamental objectives, and instrumental goals, serving as complexity-reducing intermediate steps toward achieving terminal goals and determining eventual preferences. Notably, the hierarchical goal structure allows for contextual

BPA-FREE RANDOM CO-POLY(HYDROXYCARBONATE)

The invention pertains to a process for preparing a random co- poly(hydroxycarbonate) comprising reacting a 6-membered di-cyclic carbonate with a polyol, or a monohydric alcohol, via a ring-opening polymerization (ROP) by catalytic control for carbonate unit formation, in the presence of a catalyst, through a ring- opening polymerization reaction. Also, the invention pertains to a random co- poly(

Acoustic refurbishments in a university lecture room : Effects on speaker's comfort and voice use

Poor acoustic conditions in learning spaces have a detrimental effect on the speaker's health and constitute a risk factor for voice disorders. Previous research indicates that an acoustic refurbishment of the learning space has the potential to increase well-being and decrease voice-related health problems among teachers, but the research is scarce. In this study, we aim to investigate how differ

New zircon ages from the Tasiusarsuaq terrane, southern West Greenland

In the last three field seasons the Geological Survey of Denmark and Greenland (GEUS) has undertaken mapping in the south-eastern part of the Nuuk region in southern West Greenland, and here we present new zircon ages that help constrain the northern boundary of the Tasiusarsuaq terrane. The Archaean geology of the Nuuk region is commonly interpreted as a tectonic collage assembled through lateral

Lost (and Found) in Translation : Evaluating English translations of Mulan Shi

The classical Chinese poem Mulan Shi has been translated many times into different languages and adapted to different media. Drawing upon Sonesson’s definition of translation as a double act of communication and combining it with concepts from narratology and translation theory, we develop a framework comprising three levels of translation resemblance: (a) between the structure and content of the

Contrast and Contrast Variation in Neutron, X-ray, and Light Scattering

The concept of scattering contrast is central to (small-angle) scattering of neutrons, X-rays, and visible light, as it defines the visibility to the radiation of the nano- and mesostructures under scrutiny, in their respective solvent or matrix. In this chapter, we start with the scattering process by elementary scatterers, such as nuclei or atoms, which produce secondary, scattered waves, and th

Zircons of the Sörvik granite – a link between the young Trans-scandinavian Igneous Belt and the pre-Svecofennian

The Sörvik granite forms rounded intrusions in the dominating Revsund granite, north-eastern Jämtland, central Sweden. Laser-ablation single-collector magnetic sector field-inductively coupled plasma-mass spectrometry on zircons was used to date the granite. The zircons are inhomogeneous, some with evident cores. The fractionation curves, 207Pb/235U versus time (depth), are irregular and often inc

Complexities and span of crystallization ages of a non-foliated Svecofennian granite pluton

Upper-intercept U-Pb ages (TIMS) of two non-foliated I-type granites are 1887 ± 20 Ma (part of a granodiorite-granite sequence) and 1881 ± 2 Ma (leucogranite with transitions into pegmatite). A non-foliated S-granite, which according to field observations, is younger than the two I-granites, occurs within the same composite pluton. Zircons of this granite are heterogeneous and contain abundant cor

Experimental Analysis of Multipath Characteristics in Indoor Distributed Massive MIMO Channels

Distributed multiple-input multiple-output (MIMO), also known as cell-free massive MIMO, has emerged as a promising technology for sixth-generation (6G) wireless networks. This letter introduces an indoor channel measurement campaign designed to explore the behavior of multipath components (MPCs) in distributed MIMO channels. Fully coherent channels were measured between eight distributed uniform

Preliminary Archaeopetrological Study of the Lithic Industry from the l’Hort de la Boquera Rock Shelter (Margalef de Montsant, Tarragona, Spain) : Applying Mineralogical and Geochemical Techniques

The l’Hort de la Boquera site is located in the northeastern part of Iberia and its stone tool assemblage includes up to 25,000 flint artefacts. This is the first approach to the analysis of the raw material through an archaeopetrological study. Results were obtained by use of mineralogical techniques: macroscopic and petrographic analysis, Scanning Electronic Microscopy (SEM), Micro-Raman and X-R

Time Management and Personal Efficiency in the Age of Computational and Systems Oncology

The rapid advancement of medicine, fueled by big data and interdisciplinary research, has significantly transformed the landscape of computational oncology research. In this evolving environment, effective time management strategies are essential for researchers across diverse specializations. Computational oncology researchers typically pursue one of three primary career paths: clinical medicine,