Protein S deficiency is an autosomal dominant disorder that results from mutations in the PROS I gene. Conventional mutation detection techniques fail to detect a pathogenic PROSI mutation in approximately 50% of cases. The present study investigates whether large deletions of PROS I are found in families where mutations in the PROS I gene have not been found despite sequencing. For this purpose,

The diversion of pancreatic juice and bile stimulates pancreatic exocrine secretion but the mechanism behind this process is still not clear. The present study investigates the influence of long lasting (10 h) bile diversion or pancreatic juice and bile diversion on the pancreatic secretion in conscious pigs. The experiments were performed on 4 weaned piglets, which had a catheter inserted to the

I-131 radionuclide therapy studies have not shown a strong relationship between tumor absorbed dose and response, possibly due to inaccuracies in activity quantification and dose estimation. The goal of this work was to establish the accuracy of I-131 activity quantification and absorbed dose estimation when patient-specific, 3-dimensional (3D) methods are used for SPECT reconstruction and for abs

In this paper the predictive capability of the smoke transport model CFAST 2.0 is evaluated for five different scenario configurations. The evaluation is made by statistical analysis according to a methodology presented in an earlier paper. Model predictions and experimental data, previously published, are compared and quantitative measures of the predictive capability are thus derived. With the q

The Rhodobacter capsulatus BchI protein is one of three subunits of Mg chelatase, the enzyme which catalyzes the first committed step of chlorophyll and bacteriochlorophyll biosynthesis. The BchI protein was produced with an inducible T7 RNA polymerase expression system in Escherichia coli. The protein was purified from the soluble cell-extract fraction and crystallized from polyethylene glycol so

Impaired appetite and weight changes are commonly seen in patients with depression, but the pathophysiology behind this imbalance between energy intake and energy expenditure remains largely unknown. The aim of this paper is to review the literature regarding a possible role for cytokines in the regulation of appetite and body weight, with special emphasis on depression. There now exists a substan

This is a study of the second century AD literary work 'Periegesis Hellados', i.e. description of, or guide to, Greece, written by the otherwise unknown author Pausanias. This is a purely textual study with the whole of the Periegesis as its object. It falls into two parts. In part one we study the frame narrative. The current views on the 'theoremata' and 'logoi' in the Periegesis is reconsidere

Case study is an important research methodology for software engineering. We have identified the need for checklists supporting researchers and reviewers in conducting and reviewing case studies. We derived checklists for researchers and reviewers respectively, using systematic qualitative procedures. Based on nine sources on case studies, checklists are derived and validated, and hereby presented

Purpose: Desmopressin is a well established and effective therapy for nocturnal enuresis. Water intoxication leading to hyponatremia is an infrequent but serious adverse event associated with desmopressin. We assessed the safety of desmopressin in children 18 years or younger with nocturnal enuresis with a focus on the relative safety of the oral compared with the intranasal formulation. Materials

Introduction: Impacted morselized bone allograft is thought to be remodeled to a great extent. We have previously shown that load-bearing increases the remodeling of impacted morselized bone allografts in a rabbit knee prosthesis model. Bone Morphogenic Proteins (BMPs) also stimulate bone formation and bone allograft remodeling. In this study, our aim was to determine whether it was possible to in

I denna artikel har jag försökt visa att när man engagerar sig i en politisk rörelse spelar emotioner en inte obetydlig roll. Ty den fråga man måste ställa sig är om det är troligt att känslorna inte har någon betydelse för de personer som är aktiva i föreningar av olika slag? Tron att passion och emotioner har en betydelse för engagemanget kan ses som ett alternativ till uppfattning att det är ”i

Some raw material characteristics were evaluated in three apple varieties cultivated in Southern Sweden, namely Kim, Mutsu and Jonagold. The study was undertaken to collect information in order to identify the effects of initial tissue properties on mass transport phenomena in general, and osmotic processing responses in particular. The texture profile analysis revealed cortex anisotropy of the th

The Swedish function word 'att' tends to be phonetically marked in hesitation contexts. The relation between such contexts and the syntactic complexity of the following clause is discussed.

Arbetarförfattare skriver deckare och når en bred publik. Men man kan lika väl säga att de förvandlar sig till underhållningsförfattare. Kanske går de under för en borgerlig kultur på samma sätt som när modernismen blev viktigare än klassen i litteraturen i mitten av förra seklet. Vänstern måste bygga upp sina egna kulturella institutioner om dagens arbetarlitteratur ska vidareutvecklas. Magnus Ni