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Associations Between Added Sugar Intake and Risk of Four Different Cardiovascular Diseases in a Swedish Population-Based Prospective Cohort Study

Aims: Although diet is one of the main modifiable risk factors of cardiovascular disease, few studies have investigated the association between added sugar intake and cardiovascular disease risk. This study aims to investigate the associations between intake of total added sugar, different sugar-sweetened foods and beverages, and the risks of stroke, coronary events, atrial fibrillation and aortic

Analysis of the IL28RA locus as genetic risk factor for multiple sclerosis

Recently, we reported an association between a SNP in IL28RA and MS. Here, we performed a fine-mapping of the IL28RA locus by genotyping 10 haplotype-tagging SNPs in a Basque-Spanish population. In addition, based on shared genetic risk loci between autoimmune diseases, a psoriasis-associated SNP located at this locus, rs4649203, was genotyped in four independent populations, comprising a total of

The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis

The IL22RA2 locus is associated with risk for multiple sclerosis (MS) but causative variants are yet to be determined. In a single nucleotide polymorphism (SNP) screen of this locus in a Basque population, rs28385692, a rare coding variant substituting Leu for Pro at position 16 emerged significantly (p = 0.02). This variant is located in the signal peptide (SP) shared by the three secreted protei

Potential rents vs. potential lives

The seeking of potential rents directs flows of investment into built and natural environments, suffusing volatility into urban and rural landscapes, generating gentrification and other forms of land use change, and displacing lives and livelihoods to make space for ‘improvement’, ‘highest and best use’, ‘revitalization’, or the like. In this paper we argue that potential rents are captured at the

Self-powered photo-thermo electrochemical sensor for harvesting of low photo thermal energy

An ecofriendly design of low-cost electrochemical sensor activated by low-grade photo-thermal energy can be a prime stepping-stone for the perspective developments of various renewable energy conversion and utilization schemes. In this study, an investigation of n-type indium arsenide (n-InAs)/aqueous solution of orange dye (OD)/Zinc (Zn) sensor was carried out at various molarities of 1, 2, and 3

Celebrating the contributions of Govindjee after his retirement : 1999–2020

Govindjee, Professor Emeritus of Biochemistry, Biophysics and Plant Biology at the University of Illinois at Urbana-Champaign since 1999, is renowned for his pioneering work in the light reactions of photosynthesis and important accomplishments as educator, editor, historian and advocate of photosynthesis. In his honour, we review his contributions over the last twenty years, which were often achi

RIFM fragrance ingredient safety assessment, 2-cyclohexylcyclohexanone, CAS Registry Number 90-42-6

Summary: The existing information supports the use of this material as described in this safety assessment. 2-Cyclohexylcyclohexanone was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data and read-across to 2-tert-butylcyclohexanone (CAS # 1728-46-7) show that 2

Iran’s Killing Machine: Political Assassinations by the Islamic Regime

It was recently revealed that the Iranian regime was planning to assassinate the US ambassador to South Africa. Tehran denied any such plans, but a brief look at the Islamic regime’s history shows that Iran not only has the will but also the means to conduct assassinations on foreign soil.Assassinations and terrorism have been the regime’s modus operandi both at home and abroad ever since the esta

Childhood sexual abuse. An evaluation of a two-year group therapy in adult women

Twenty-two female psychiatric outpatients with experiences of childhood sexual abuse took part in a two-year group therapy. All Completed therapy. At the end of therapy the women's psychiatric symptoms were reduced and their social interaction and adjustment were improved. They evaluated relationships to their children, partners and friends to be improved.

One-year follow-up of significant others of suicide attempters

Background: In a previous study we interviewed significant others (SOs) directly following a patient's suicide attempt as a part of the psychiatric assessment. SOs added important information to the assessment and they needed professional counselling themselves. In the present study the opinions of SOs were investigated 1 year after a suicide attempt. Methods: Semi-structured interviews of 84 SOs

The use and reporting of neonatal pain scales : a systematic review of randomized trials

ABSTRACT: The burden of pain in newborn infants has been investigated in numerous studies, but little is known about the appropriateness of the use of pain scales according to the specific type of pain or infant condition. This systematic review aimed to evaluate the reporting of neonatal pain scales in randomized trials. A systematic search up to March 2019 was performed in Embase, PubMed, PsycIN

Supplemental Instruction (SI) in Europe: An Overview of Current SI Programmes

Supplemental Instruction (SI) is a 47-year old proven peer-learning model that addresses student engagement, performance and retention as well as the transition to Higher Education (HE). SI was developed at the University of Missouri Kansas City in the US and has received wide recognition. Today the method has practitioners all over the United States as well as in several other countries around th