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Dysregulation of Placental Lipid Hydrolysis by High-Fat/High-Cholesterol Feeding and Gestational Diabetes Mellitus in Mice

Advanced maternal age and obesity are the main risk factors to develop gestational diabetes mellitus (GDM). Obesity is a consequence of the increased storage of triacylglycerol (TG). Cytosolic and lysosomal lipid hydrolases break down TG and cholesteryl esters (CE) to release fatty acids (FA), free cholesterol, and glycerol. We have recently shown that intracellular lipases are present and active

What is the language of sound like?

While sensory perception is currently receiving quite a lot of attention across disciplines, little empirical research has focused on how people describe auditory experiences. Research on the representation of sound in fiction narratives has shown that sounds are frequently conceptualized as events whose descriptions are instantiated in domains other than sound proper, as in strong men banging the

Methods for Analysing Steering Effects of Global Goals

This chapter provides an overview of the multi-faceted landscape of methods used to study the steering effects of the Sustainable Development Goals. After a discussion of the political use of science and the complex relations between science and politics, the chapter showcases a selection of different methods that are employed to trace the steering effects of the Sustainable Development Goals. Sel

Brand Movement

The paper conceptualizes, via the notion of brand movement, the process in which consumers-citizens turn to brands to deal with political frustrations and in which brands have the power to channel, coordinate, and mobilize these consumers.

Optimal sensor placement for localizing structured signal sources

This work is concerned with determining optimal sensor placements that allow for an accurate location estimate of structured signal sources, taking into account the expected location areas and the typical range of the parameters detailing the signals. In the presentation, we illustrate the technique for tonal sound signals, exploiting the expected harmonic structure of such signals. To determine p

Biventricular Pressure-Volume Loop Assessment Before and After Pulmonary Valve Replacement in Tetralogy of Fallot

Patients with tetralogy of Fallot (TOF) may undergo pulmonary valve replacement (PVR) after initial full repair. We investigated indices of biventricular function, work and efficiency of TOF patients' using noninvasive pressure-volume (PV) loop analysis on cardiovascular magnetic resonance (CMR) images and compared pre-and post PVR groups. Biventricular segmentations of steady state free precessio

The Study of Global Environmental Politics : Strategies for Research and Learning

Contemporary research and teaching on global environmental politics (GEP) draw upon many approaches to understanding the ways in which states and societies respond to transboundary environmental problems (see Chapter 2). Approaches that emphasize the state (see Chapter 7) and international organizations (see Chapter 8) derive in a straightforward way from scholarly work in international relations

Multilevel Climate Governance in Brazil and Indonesia : Domestic Pioneership and Leadership in the Global South

Focusing on forest policy and urban climate politics in Brazil and Indonesia, the primary objective of this chapter is to identify domestic pioneers and leaders who, compared to other sectors, governmental levels or jurisdictions within the same nation-state, move ‘ahead of the troops’ (Liefferink and Wurzel, 2017: 2-3). The chapter focuses especially on the role of multilevel governance in bringi

Institutional Interlinkages

Given the regulatory gap in earth system governance, numerous new governance initiatives, such as multilateral clubs, private certification schemes and multi-stakeholder forums, have emerged to tackle transboundary environmental challenges. This plethora of different governance initiatives has led to a significant increase in the institutional complexity of global (environmental) policymaking and

REDD+ and the Reconfiguration of Public Authority in the Forest Sector : A Comparative Case Study of Indonesia and Brazil

Since the 1980s, central governments have decentralized forestry to local governments in many countries of the Global South. More recently, REDD+ has started to impact forest policy-making in these countries by providing incentives to ensure a national-level approach to reducing emissions from deforestation and forest degradation. Höhne et al. analyze to what extent central governments have rebuil