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Contract-Boundary-Spanning Governance Mechanisms: Conceptualizing Fragmented and Globalized Production as Collectively Governed Entities

Conceptualizing how private actors can and should control their supply chains is a tricky question with both economic and legal dimensions. The topic is of extreme importance in today's global economy. On the one hand, this importance is highlighted by events such as the catastrophic and deadly collapse of the Rana Plaza factory building in Bangladesh and the economic fiasco of the Olkiluoto 3 nuc

Towards a Genealogy and Typology of Governance Through Contract Beyond Privity

Contracts are used to extend governance on supply chain and platform actors in ways that could not be envisaged when the foundations of current conceptualizations of contractual privity were laid down in the 19th century. This results in a stark contradiction. Firms use contracts to extend governance on actors beyond privity when it suits their interests, for example for reasons of supplychain-wid

Creative Work and Social Innovation : The Case of Innovating in an Open-Air Museum

The public management of urban space is an everyday practice that requires development. But how is creative work done in a public context? The idea of offering outdoor offices and outdoor conferences is being implemented in an open-air museum, owned by a middle-sized city in Sweden. This chapter focuses on their ambitions to be innovative, and the practices officials engage in, to innovate. The et

Sustainable Business Model Design – Patterns to Make Sustainability Work

Businesses are an essential driver for sustainability, yet managers struggle to make decisions about their business model that actually improve their sustainability performance. In this episode, we meet Florian Lüdeke-Freund, Henning Breuer, and Lorenzo Massa, authors of the new book called ‘Sustainable Business Model Design’. They introduce the concept of sustainable business model patterns, to s

Galectin-9 Signaling Drives Breast Cancer Invasion through Extracellular Matrix

Aberrations in glycan and lectin expression and function represent one of the earliest hallmarks of cancer. Among galectins, a conserved family of β-galactoside-binding lectins, the role of Galectin-9 in immune-tumor interactions is well-established, although its effect on cancer cell behavior remains unclear. In this study, we assayed for, and observed, an association between Galectin-9 expressio

Income Inequality and Carbon Emissions in the United States 1929–2019

This paper studies the relationship between income inequality and carbon emissions in the United States between 1929 and 2019. We contribute to the literature by taking a long-term perspective, which allows us to study how the relationship has varied over time. Our results show that higher inequality was associated with lower emissions during the early part of the sample and higher emissions towarThis paper studies the relationship between income inequality and carbon emissions in the United States between 1929 and 2019. We contribute to the literature by taking a long-term perspective, which allows us to study how the relationship has varied over time. Our results show that higher inequality was associated with lower emissions during the early part of the sample and higher emissions towar

Niche complementarity drives increases in pollinator functional diversity in diversified agroforestry systems

Rising demand for food production poses a major threat to biodiversity by placing competing pressures on land. Diversified farming systems are one widely promoted nature-based solution to this challenge, which aim to integrate biodiversity-based ecosystem services into agricultural production. The underlying theory behind this approach is that diverse communities enhance ecosystem service provisio

Activated CD8+CD38+ Cells Are Associated With Worse Clinical Outcome in Hospitalized COVID-19 Patients

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), that spread around the world during the past 2 years, has infected more than 260 million people worldwide and has imposed an important burden on the healthcare system. Several risk factors associated with unfavorable outcome were identified, including elderly age, selected comorbidities, immune suppression as well as laboratory markers.

Deviations from the extended London model at high magnetic fields in YBa2Cu3 O7

We report on the evolution with the magnetic field and the temperature of the vortex lattice (VL) in fully oxygenated YBa2Cu3O7 as studied by time-of-flight small-angle neutron scattering. Using the High Field Magnet/Extreme Environment Diractometer beamline at Helmholtz-Zentrum Berlin, we have obtained data up to 25.9 T - much higher than data available previously. Our VL structure results are co

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Extent of Lymphadenectomy and Long-Term Survival in Esophageal Cancer

OBJECTIVE: To examine the hypothesis that survival in esophageal cancer increases with more removed lymph nodes during esophagectomy up to a plateau, after which it levels out or even decreases with further lymphadenectomy.SUMMARY BACKGROUND DATA: There is uncertainty regarding the ideal extent of lymphadenectomy during esophagectomy to optimize long-term survival in esophageal cancer.METHODS: Thi

Decreasing resection rates for nonmetastatic gastric cancer in Europe and the United States

BACKGROUND: Resection is the cornerstone of curative treatment for many nonmetastatic gastric cancers (GCs), but the population treatment patterns remains largely unknown. This large international population-based study aimed at investigating the treatment patterns and trends for nonmetastatic GC in Europe and the United States and at exploring factors associated with resection.METHODS: Data of pa

Geographical differences in cancer treatment and survival for patients with oesophageal and gastro-oesophageal junctional cancers

BACKGROUND: Only around one-quarter of patients with cancer of the oesophagus and the gastro-oesophageal junction (GOJ) undergo surgical resection. This population-based study investigated the rates of treatment with curative intent and resection, and their association with survival.METHODS: Patients diagnosed with oesophageal and GOJ cancer between 2006 and 2015 in Sweden were identified from the

Modern roles for an ancient system. Intracellular Complement in the regulation of β cell function

Type 2 diabetes (T2D) is characterised by defective insulin exocytosis from the pancreatic β cells, accompanied by insulin resistance. Reduced β cells mass is often seen in T2D individuals, caused by enhanced β cells apoptosis. It is now understood that several components drive β cells dysfunction and apoptosis. These are glucose-and lipo-toxicity, ER stress, pro-inflammatory cytokines, dysfunctio

‘Spatial methodology’ in religion and belief research : the example of a study of Twelver Shii Muslim networks in Britain

This chapter discusses recent debates on the development of a spatial methodology in the study of diasporic religions and its use in research on minority religious communities, their transnational dimensions and their place and role in public life. These contributions are used to understand the multiple spatial layers in which transnational religious networks are located and to question some of th

From Irish Exceptionalism to European Normality? : The New Islamic Presence in the Republic of Ireland

Due to its colonial past, Ireland has often been described as an exceptional state in Western Europe. The discourse of Irish exceptionalism also suggests a smoother path of integration for Muslim migrants compared to other Western European countries. Apart form providing an overview of Muslim immigration to the Republic of Ireland in the last 20 years, the paper critically engages with the discour

Experiences of Muslims in Western Europe

The chapter provides an overview of the development of the Muslim presence in Western Europe focussing on the period after World War II. The discussion deals with the experiences of Muslims in 19 countries which were located West of the “iron curtain” during the Cold War era (1946/1947–1989) and were therefore integrated in the capitalist world order and politically aligned with the USA. Beginning