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Riboflavin (vitamin B2) is an important constituent of the prosthetic groups flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN), which are utilized as electron-carriers in energy metabolism. Excitation by UV-light leads to the generation of riboflavin radicals and reactive oxygen species (ROS), which can oxidize a wide range of biomolecules. The human protein α1-microglobulin (A1M)

This introduction positions the essays in this special issue in relation to Pascale Casanova’s model of inequality and value in the world republic of letters. Arguing that the vernacular has been an overlooked or underelaborated concept in subsequent world literary theorizations, the essay then proceeds to discuss the shifting value and nature of the vernacular–a concept that only has meaning if i

Dopaminergic neurons (DAns), generated from human pluripotent stem cells (hPSCs), are capable of functionally integrating following transplantation and have recently advanced to clinical trials for Parkinson's disease (PD). However, pre-clinical studies have highlighted the low proportion of DAns within hPSC-derived grafts and their inferior plasticity compared to fetal tissue. Here, we examined w

Background G protein-coupled estrogen receptor (GPER), or G protein-coupled receptor 30 (GPR30), is reported to mediate non-genomic estrogen signaling. GPR30 associates with breast cancer (BC) outcome and may contribute to tamoxifen resistance. We investigated the expression and prognostic significance of GPR30 in metachronous contralateral breast cancer (CBC) as a model of tamoxifen resistance. M

Writing Urban Places proposes an innovative investigation and implementationof a process for developing human understanding ofcommunities, their society, and their situatedness. By recognising thevalue of local urban narratives – stories rich in information regardingcitizens socio-spatial practices, perceptions and expectations – theAction aims to articulate a set of concrete literary devices with

The interest of in vivo measurements of fat has increased over the years due to the increasing prevalence of obesity and obesity-related conditions such as diabetes, cardiovascular disease, and fatty liver. The relationship between the accumulation of adipose tissue within the different depots and organs of the body, and the risk of developing numerous diseases, has been investigated and establish

The traditional parametric approach to Granger causality (GC), based on linear vector autoregressive modeling, suffers from difficulties related to the inaccurate modeling of the generative process. These limits can be solved by using nonparametric spectral estimates in the frequency-domain formulation of GC, also known as spectral GC. In a simulation study, we compare the mean square error of the

How can we govern consumption and the sharing economy in our cities? This course explores cities, consumption and the sharing economy in Europe and around the world. We connect together the key themes of the sharing economy, cities, governance, consumption and urban sustainability. We explore how the sharing economy can contribute to increasing social, environmental and economic sustainability. An

Summary: We studied effectiveness of osteoporosis treatment in women older than 80 years, who often are not included in clinical trials. Treatments were as effective on bone density and fractures as in younger women. Introduction: To study real-world effectiveness of osteoporosis treatment on BMD and fractures in the oldest old women (≥ 80 years) compared with women (60–79 years) in the clinical s

Rationale and aims: The Quality of Dyadic Relationships is a self-assessment scale used to evaluate various aspects of relationship quality. Psychometric evaluation by the developers of the instrument has led to a nontested amended version. Further psychometric testing is thus warranted, and the aim of this study was to evaluate homogeneity, construct validity (in terms of concurrent, discriminant

All the analytic methods for assessing the safety or comfort of bicyclists in urban area have as a common factor the number of bicycles that enter the system in a certain time interval or an estimate of that. The estimation of the average bicycle volume based on manual and automatic measurements is time-consuming and often require the use of expensive technology. The paper presents a method of est

To establish the contribution of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) for the incretin effect after oral glucose, studies were undertaken in female mice with genetic deletion of receptors for GIP and GLP-1 (double incretin receptor knockout [DIRKO] mice) and their wild-type (WT) counterparts. Insulin secretion was explored after oral glucose (doses

Aim: To investigate if communication ability and method were related to each other and to age, sex, gross motor function, or manual ability in children with cerebral palsy. Method: This cross-sectional study used data registered in the Swedish Cerebral Palsy Surveillance Program registry, involving 3000 children aged 0 to 18 years. Pearson’s χ2 test and Spearman’s correlation were used to test ass

Novel oxygen-deficient double-perovskite type oxide Ba2NixCo2−xO6 was applied to produce O2/CO2 mixed stream gas for oxyfuel combustion application. A series of different Co concentration substituted Ba2NixCo2−xO6 was synthesized by an EDTA-citrate sol-gel combustion method. The oxygen carriers, Ba2Ni0.25Co1.75O6, Ba2Ni0.45Co1.55O6, Ba2Ni0.65Co1.35O6 and Ba2Ni0.85Co1.15O6 were c\characterized by s

Background. In Sweden, both glucose analyzers in accredited laboratories and point-of-care glucose devices are used for gestational diabetes mellitus (GDM) diagnosis. The aim of this study was to compare the diagnostic performance of the HemoCue Glucose 201+ (HC201+) and RT (HC201RT) systems with that of the hospital central laboratory hexokinase method (CL) based on lyophilized citrate tubes, usi