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Frequent finding of the androgen receptor A645D variant in normal population.

Background: The androgen receptor A645D mutation has been described in one patient with ambiguous genitalia and one boy with normal phenotype. Objective: Because of this phenotypic variation, we screened a cohort of men from the general population (n = 293) as well as men with the following disorders of the genital tract for the mutation: men with prostate cancer (n = 89), testicular cancer (n = 8

Integrating DNA data and traditional taxonomy to streamline biodiversity assessment: an example from edaphic beetles in the Klamath ecoregion, California, USA

Conservation and land management decisions may be misguided by inaccurate or misinterpreted knowledge of biodiversity. Non-systematists often lack taxonomic expertise necessary for an accurate assessment of biodiversity. Additionally, there are far too few taxonomists to contribute significantly to the task of identifying species for specimens collected in biodiversity studies. While species level

Non-Hodgkin's lymphoma in systemic lupus erythematosus

Background: Recent evidence supports an association between systemic lupus erythematosus (SLE) and non-Hodgkin's lymphoma (NHL). Objectives: To describe demographic factors, subtypes, and survival of patients with SLE who develop NHL. Methods: A multi-site cohort of 9547 subjects with definite SLE was assembled. Subjects at each centre were linked to regional tumour registries to determine cancer

Lipid metabolism in the pancreatic beta-cell. Implications for insulin secretion.

We have investigated the role of lipid metabolism with regard to beta-cell function and insulin secretion. Lipids are known to play a crucial functional role in the pancreatic beta-cell, where they are essential for adequate hormone release, but may also exert a long-term toxic effect, leading to beta-cell dysfunction. Our studies in mice, where insulin resistance and glucose intolerance was induc

Bose-Einstein correlations in the Lund model

By providing the Lund Model fragmentation process with a quantum-mechanical framework we extend the results of previous work to situations where there are very many identical bosons. We investigate the features of the weight distributions in some detail and in particular exhibit three-particle BE-correlations, the influence on the rho-spectrum and the difference between charged and neutral pion co

Weichselian glaciations in the middle Notec River region, northwest Poland

Popular Abstract in Swedish Nedisningar under Weichsel-istiden kring floden Notec i nordvästra Polen. Inlandsisar är en viktig komponent i jordens klimatsystem. Deras utbredning och rörelsemekanismer styrs till stor del av klimatet samtidigt som isarna i sin tur också påverkar klimatsystemet. Genom kunskap om hur inlandsisarna växte till och smälte av under den senaste istiden kan man utvärdera oThis thesis presents results of studies on the ice flow pattern and ice movement mechanism during the Weichselian glaciations in the middle Notec River area, NW Poland. A new lithostratigraphy of the study area has been established, based on correlation of stratigraphical position, clast lithology, fabrics and grain size composition of till units. The lithostratigraphy covers two glacial advances

On the evolution of conditional dispersal under environmental and demographic stochasticity

Questions: How will density-dependent and costly dispersal evolve in populations subject to local density regulation and environmental stochasticity? What type of density response will evolve, a strong threshold type response or a soft response gradually increasing dispersal? Method: An individual-based model including density dependence, environmental fluctuations, and population variation was us

Sivar Arnér - den livsbejakande nihilisten

Sivar Arnér tar i sitt tidiga författarskap (1943–56) upp frågor och motiv som liknar existentialismens: främlingskapet inför världen, de absurda handlingarna, den starka livsviljan och insikten att världen är ett kaos. I samtliga verk från fyrtio- och femtiotalet, även de hörspel som har ett politiskt budskap, beskriver han människor som kämpar med en svår livssituation. Oftast hakar de upp livsm

Biofuels for Transport in Europe: Lessons from Germany and the UK

The utilisation of biofuels is attracting growing support from the European Union and member states as a strategy to tackle climate change, enhance energy security, and contribute to regional development. This paper describes, compares, and analyses the markets for biofuels in Germany and the UK. The introduction of biofuels for transport in these member states provides contrasting pictures, and t

Evidence of a defined spatial arrangement of hyaluronate in the central filament of cartilage proteoglycan aggregates

Aggregates of proteoglycans from the Swarm rat chondrosarcoma reassembled in vitro have been studied by rotary-shadowing electron microscopy, and shown to be similar to native structures that have never been dissociated [Morgelin, Engel, Heinegard and Paulsson (1992) J. Biol. Chem. 267, 14275-14284]. A hyaluronate with defined chain length (HAshort) has now been prepared by autoclaving high-Mr hya

Ross operation for bicuspid aortic valve disease in adults: is it a valid surgical option?

OBJECTIVE: The validity of the Ross operation as freestanding root replacement in adult patients with bicuspid aortic valve disease has lately been questioned. We have analyzed retrospectively our results in 23 adult patients (19 males) operated for bicuspid aortic valve disease ad modum "Ross" employing a freestanding root replacement technique. DESIGN: In 9 patients the dominant aortic valve les

Öresundsregion - bli till! : De geografiska visionernas diskursiva rytm

Popular Abstract in Swedish Avhandlingens syfte är att kartlägga och analysera hur geografiska visioner utgjort diskursiva redskap i en specifik framtidsorienterad process, institutionaliseringen av Öresundsregionen.This thesis is about how geographical visions worked as discursive tools in the institutionalisation of the Öresund Region. The geographical vision is defined as a cognitive set of imagined and material pictures of the future structured as a spatial whole. The geographical vision is, in addition to this, a spaceconfiguration-, power-, and disciplinary - instrument, and, the product of a discursiv

Hyades dynamics from N-body simulations: Accuracy of astrometric radial velocities from Hipparcos

The internal velocity structure in the Hyades cluster as seen byHipparcos is compared with realistic N-body simulations using the NBODY6code, which includes binary interaction, stellar evolution and theGalactic tidal field. The model allows to estimate reliably the accuracyof astrometric radial velocities in the Hyades as derived by Lindegrenet al. (cite{lindegren00}) and Madsen et al. (cite{madse