We have reconstructed the distribution of extraterrestrial chrome spinels in a marine limestone section across the Frasnian–Famennian stratotype section at Coumiac in southern France, providing the first insights on the types of micrometeorites and meteorites that fell on Earth at this time. The data can test whether the small cluster of roughly coeval, large impact structures is related to an ast

The mineralo-sphere is an important micro habitat in terrestrial ecosystems. How different groups of microorganisms colonise mineral surfaces and whether the level of grassland land-use intensity (LUI) modifies this micro-habitat is not well known, however. We exposed mesh containers filled with pristine soil minerals (illite/goethite) mixed with 13C labelled root litter of Dactylis glomerata and

Protandry, the earlier arrival of males at the breeding grounds relative to females, is common in migratory birds. However, due to difficulties in following individual birds on migration, we still lack knowledge about the spatiotemporal origin of protandry during the annual cycle, impeding our understanding of the proximate drivers of this phenomenon. Here, we use full annual cycle tracking data o

Hox genes are a remarkable example of conservation in animal development and their nested expression along the head-to-tail axis orchestrates embryonic patterning. Early in vertebrate history, two duplications led to the emergence of four Hox clusters (A-D) and redundancy within paralog groups has been partially accommodated with gene losses. Here we conduct an inventory of squamate Hox genes usin

The incidence of stroke and dementia are diverging across the world, rising for those in low- and middle-income countries and falling in those in high-income countries. This suggests that whatever factors cause these trends are potentially modifiable. At the population level, neurological disorders as a group account for the largest proportion of disability-adjusted life years globally (10%). Amon

The number of publications in the field of chemical cross-linking combined with mass spectrometry (XL-MS) to derive constraints for protein three-dimensional structure modeling and to probe protein-protein interactions has increased during the last years. As the technique is now becoming routine for in vitro and in vivo applications in proteomics and structural biology there is a pressing need to

In a rapidly digitalizing world, the increasing importance of online information channels is repeatedly stated. But little is known about the procedure of online information search. This study examines the process of booking a journey via digital devices. It is based on a multi-method approach including interview and experiment. Results show that tourists’ online searching behaviour is less ration

Background: In recent years, there has been growing awareness of the distinct characteristics of adolescents and young adults (AYA) diagnosed with cancer. Soft-tissue sarcoma (STS) accounts for approximately 1% of all cancers diagnosed in adults and 8% of cancers diagnosed in AYA. To the best of our knowledge, only a few sarcoma registers include data regarding histological subtype, age at diagnos

Purpose: Epidemiologic evidence supports an association between high mammographic density and increased breast cancer risk yet etiologic mechanisms remain largely unknown. Mixed evidence exists as to whether circulating lipid levels influence mammographic density and breast cancer risk. Therefore, we examined these associations in the Nurses’ Health Study (NHS) and Nurses’ Health Study II (NHSII),

Background: Genome-wide association studies (GWAS) have identified >50 single nucleotide polymorphisms (SNP) in association with estimated glomerular filtration rate (eGFR) and chronic kidney disease (CKD) but little is known about whether the combination of these SNPs may aid in prediction of future incidence of CKD in the population. Methods: We included 2301 participants with baseline eGFR ≥60

Motivation: Comparisons of microbiome communities across populations are often based on pairwise distance measures (beta-diversity). Standard analyses (principal coordinate plots, permutation tests, kernel methods) require access to primary data if another investigator wants to add or compare independent data. We propose using standard reference measurements to simplify microbiome beta-diversity a

Background: Although free fatty acids have been positively associated with risk factors for stroke, the role of plasma free fatty acids in the development of stroke has not been elucidated in older adults. Aims: We sought to examine the association between plasma free fatty acids and incident stroke. Methods: Prospective cohort of 4369 men and women ≥65 years of age in the Cardiovascular Health St

Background: Widespread implementation of Alzheimer's disease biomarkers in routine clinical practice requires the establishment of standard operating procedures for pre-analytical handling of cerebrospinal fluid (CSF). Methods: Here, CSF collection and storage protocols were optimized for measurements of β-amyloid (Aβ). We investigated the effects of (1) storage temperature, (2) storage time, (3)

This thesis treats the intersection between two of the largest transformations we are seeing within our society today; the cloud and the Internet-of-Things (IoT). The aim of this thesis is to investigate different ways to model and control a network of cloud services so that timing-critical IoT applications can make use of them. Examples of such applications can be autonomous and mobile robots, sm

Context. Although there have been numerous studies of chemical abundances in the Galactic bulge, the central two degrees have been relatively unexplored due to the heavy and variable interstellar extinction, extreme stellar crowding, and the presence of complex foreground disk stellar populations. Aims. In this paper we discuss the metallicity distribution function, vertical and radial gradients,

Discussions and debates about traditional values of equity and inclusion have increased in recent years, and participants in these discussions include professional heritage institutions, journalists of the daily press and the public through social media. Museums, as keepers of cultural stories and heritage under their auspices, are increasingly examining their role in shaping a narrative of divers

Hållfastheten och därmed kvaliteten på planglas varierar kraftigt beroende på förekomsten sprickor i glasets yta. Sprickorna fungerar som brottanvisningar vilket medför att man måste räkna med stora säkerhetsfaktorer då glas belastas i olika byggnadskonstruktioner. Trä som konstruktionsmaterial har en liknande problematik där man utvecklat virkessortering för att kvalitetsklassning. I den här förs