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Computational and experimental methods for deciphering the epigenetic code in hematopoietic stem cell lineage commitment

The emergence of post-genomic approaches that couple chromatin immunoprecipitation (ChIP) assays to high-throughput technique has greatly advanced our ability to investigate epigenetic features associated with normal cell development and disease. Nevertheless, these techniques exhibit some limitations. Firstly, standard protocols usually require millions of cells, thus limiting their application t

Motorfordonsförares väjningsbeteende gentemot cyklande

Under hösten 2008 genomfördes fältstudier i projektet Motorfordonsförares väjningsbeteende gentemot cyklande. Denna rapport utgör en redovisning av projektet och dess resultat. Syftet med projektet har varit att vid interaktioner mellan motorfordonsförare och cyklande studera de inblandades väjningsbeteende vid olika utformningar av cyklandes passage över gator. Fältstudierna har genomförts i formUnder hösten 2008 genomfördes fältstudier i projektet Motorfordonsförares väjningsbeteende gentemot cyklande. Denna rapport utgör en redovisning av projektet och dess resultat. Syftet med projektet har varit att vid interaktioner mellan motorfordonsförare och cyklande studera de inblandades väjningsbeteende vid olika utformningar av cyklandes passage över gator. Fältstudierna har genomförts i form

Patient throughput times and inflow patterns in Swedish emergency departments. A basis for ANSWER, A National SWedish Emergency Registry

Objective: Quality improvement initiatives in emergency medicine (EM) often suffer from a lack of benchmarking data on the quality of care. The objectives of this study were twofold: 1. To assess the feasibility of collecting benchmarking data from different Swedish emergency departments (EDs) and 2. To evaluate patient throughput times and inflow patterns. Method: We compared patient inflow patte

Organizational Learning Capabilities: Evidence from the Iranian Agricultural Higher Education System

The aim of this research is to understand and assess the application of organizational learning capabilities in the status quo and review desirable situations in the context of the agricultural faculty environment. Data were collected from 329 faculty members in 19 public agricultural faculties using a survey questionnaire. Results indicate that organizational learning capabilities are below avera

Hormonal factors in rheumatoid arthritis – Their impact on disease risk and severity

Popular Abstract in Swedish Ledgångsreumatism är en kronisk autoimmun sjukdom, som framföra allt angriper lederna, och orsakar smärta, stelhet och svullnad. Sjukdomens svårighetsgrad kan variera kraftigt och ett vanligt sätt att värdera svårighetsgraden av sjukdomen är att mäta antikroppar (till exempel reumatoid faktor) i blodet. De som har antikroppar har oftast en svårare sjukdom än de som inteRheumatoid arthritis (RA) is 4-6 times more common in women than men during the fertile years. For women, the incidence peaks shortly after menopause, and for men the risk is greater with higher age, when androgen levels drops. Sex hormones have been suggested to play a part in the pathogenesis, since low testosterone levels have been noted in men with RA and pregnancy has an ameliorating effect o

Gender differences in facial imitation and verbally reported emotional contagion from spontaneius to emotinally regulated processing levels

Previous studies on gender differences in facial imitation and verbally reported emotional contagion have investigated emotional responses to pictures of facial expressions at supraliminal exposure times. The aim of the present study was to investigate how gender differences are related to different exposure times, representing information processing levels from subliminal (spontaneous) to suprali

Extended staphylococcal enterotoxin D expression in ham products.

Staphylococcal enterotoxin D (SED) is one of the most frequently recovered enterotoxins in staphylococcal food poisoning (SFP) outbreaks. The expression and production of SED were investigated in three ham products, i.e. boiled ham, smoked ham and dry-cured Serrano ham incubated at room temperature for seven days. Staphylococcus aureus was also, as a reference, grown in cultivation broth during op

Description and performance of an electron-ion coincidence TOF spectrometer used at the Brazilian synchrotron facility LNLS

This paper reports the characteristics and performance of a Time-of-Flight Mass Spectrometer (TOF-MS) for coincidence measurements between electrons and ions that has been developed jointly in Sweden and Brazil. The spectrometer, used for studies of inner-shell photoexcitation of molecules in the gas-phase, has been optimized by implementing ion and electron lenses to allow the use of relatively s

Competitive physical activity early in life is associated with bone mineral density in elderly Swedish men

In this population-based study of 75-year-old men (n = 498), we investigated the association between physical activity (PA) early in life and present bone mineral density (BMD). We demonstrate that a high frequency of competitive sports early in life is associated with BMD at several bone sites, indicating that increases in BMD following PA are preserved longer than previously believed. Introducti

Ultrasmall Silver Nanopores Fabricated by Femtosecond Laser Pulses

Ultrasmall nanopores in silver thin films with a diameter of about 2 nm have been fabricated using femtosecond laser ablation in liquid. Ultrafast laser pulse ablation generates highly nonequilibrium excitated states, from which silver thin films emerge and progressively grow with the assistance of capping agent molecules. During this growth process, capping agent molecules are enclaved within the

Different arbuscular mycorrhizal inoculants affect the growth and survival of Podocarpus cunninghamii restoration plantings in the Mackenzie Basin, New Zealand

There is increasing interest in the use of arbuscular mycorrhizal fungi (AMF) for ecological restoration, as AMF can improve plant nutrition and growth. However, some AMF can have negative effects on plant growth. It is therefore critical that restoration strategies incorporate appropriate AMF. This research investigated differences in growth and survival of Podocarpus cunninghamii (mountain tōtar

Prediction of delivery mode by ultrasound-assessed fetal position in nulliparous women with prolonged first stage of labor

Objectives To ascertain if fetal head position on transabdominal ultrasound is associated with delivery by Cesarean section in nulliparous women with a prolonged first stage of labor. Methods This was a prospective observational study performed at Stavanger University Hospital, Norway, and Addenbrooke's Hospital, Cambridge, UK, between January 2012 and April 2013. Nulliparous pregnant women with a

On measurements of aerosol particles and greenhouse gases in Siberia and future research needs

The role of the world's boreal forest for our understanding of the climate system is indisputable. Due to the large area covered, the forest's biophysical (e.g. surface energy balance, albedo) and biogeochemical (e.g. bidirectional exchange of greenhouse gases or aerosol precursors) processes are known to affect today's climate, and will need to be accounted for in studies of climate feedbacks in

Linear dsDNA Partitions Spontaneously into the Inverse Hexagonal Lyotropic Liquid Crystalline Phases of Phospholipids.

Recently, we reported that DNA associated with inverse hexagonal (H(II)) lyotropic liquid crystal phases of the lipid 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) was actively transcribed by T7 RNA polymerase. (1) Our findings suggested that key components of the transcription process, probably the T7 RNA polymerase and the DNA, remained associated with the monolithic H(II) phase throughou