We report the first systematic investigation of relativistic effects on the UV-vis spectra of two prototype complexes for so-called photo-activated chemotherapy (PACT), trans-trans-trans-[Pt(N3)2(OH)2(NH3)2] and cis-trans-cis-[Pt(N3)2(OH)2(NH3)2]. In PACT, design of new drugs requires in-depth understanding of the photo-activation mechanisms. A first step is usually to rationalize their UV-vis spe

On a planetary scale, the D/H ratio on Mars is a key diagnostic for understanding the past history of water on the planet; locally, it can help to constrain the sources and sinks of water vapor through the monitoring of condensation and sublimation processes. To obtain simultaneous measurements of H2O and HDO lines, we have used the Echelle Cross Echelle Spectrograph (EXES) instrument aboard the S

Huvuddelen av all miljöpåverkan kan kopplas till vår konsumtion. I takt med att reallönerna ökar så ökar också konsumtionen – fler semesterresor, fler klädinköp, snabbare utbyte av produkter mot nyare versioner och så vidare. Denna utveckling utgör ett hot mot planetens tillstånd. I arbetetmed FN:s hållbarhetsmål ligger de nordiska länderna högt i den allmänna rankingen, men när det gäller delmål

Multiconfiguration Dirac-Hartree-Fock (MCDHF) calculations and relativistic configuration interaction (RCI) calculations are performed for states of the 3s23p2, 3s3p3 and 3s23p3d configurations in the Si-like ions Ti IX - Ge XIX, Sr XXV, Zr XXVII and Mo XXIX. Valence and core-valence electron correlation effects are accounted for through large configuration state function expansions. Calculated en

The cartilage aggrecan proteoglycan is crucial for both skeletal growth and articular cartilage function. A number of aggrecan (ACAN) gene variants have been linked to skeletal disorders, ranging from short stature to severe chondrodyplasias. Osteochondritis dissecans is a disorder where articular cartilage and subchondral bone fragments come loose from the articular surface. We previously reporte

Den tredje februari 2022 anordnades en workshop vars syfte var att diskutera policy rekommendationer som skulle kunna främja utvecklingen av energigemenskaper i Sverige. Under workshopen diskuterades energigemenskapers möjlighet att äga nät, incitamentsstruktur för att utveckla energigemenskaper och huruvida energiföretag bör tillåtas vara medlemmar i energigemenskaper. Deltagarna i workshopen var

BACKGROUND: Asthma is the most frequent chronic disease in children. One of the most replicated genetic findings in childhood asthma is the ORMDL3 gene confirmed in several GWA studies in several paediatric populations.OBJECTIVES: The purpose of this study was to analyse ORMDL3 variants and expression in childhood asthma in the Polish population.MATERIALS AND METHODS: In the study we included 416

This article explores the discourses, actors, and cross-border exchanges thatshape the broader landscape of contemporary transnational feminist andqueer non-governmental organizations (NGOs). While several studies havepointed to the co-opted role of NGOs, fewer have explored the potential forNGOs to influence the conditions under which they operate. That is what thisarticle sets out to do, with th

Wanting to help others and benefit society in one’s future career are examples of communal career goals. Raising these goals in youth should increase interest in HEED-occupations (Healthcare, Early Education, Domestic, and the Domestic fields) which are strongly gender-skewed and face labor shortage. Research has yet to find ways to increase communal career goals. In this study, we test the novel Wanting to help others and benefit society in one’s future career are examples of communal career goals. Raising these goals in youth should increaseinterest in HEED-occupations (Healthcare, Early Education, Domestic, and the Domestic fields) which are strongly gender-skewed and face labor shortage.Research has yet to find ways to increase communal career goals. In this study, we test the novel hy

Development of islet autoimmunity precedes the onset of type 1 diabetes in children, however, the presence of autoantibodies does not necessarily lead to manifest disease and the onset of clinical symptoms is hard to predict. Here we show, by longitudinal sampling of islet autoantibodies (IAb) to insulin, glutamic acid decarboxylase and islet antigen-2 that disease progression follows distinct tra

“The definition of insanity is doing the same thing over and over again but expecting different results.” This quote by Albert Einstein highlights our need for new formats of communication to address the knowledge-action gap regarding climate change and other sustainability challenges. This includes reflection, and communication spaces, as well as methods and approaches that can catalyze the emerg

The last half-a-century has seen a marked demand for authentic citizen participation in public policy-and decision-making, not least in the field of sustainability. The depth and forms of citizen engagement in nature-based solutions (NBS), for example, and how such participation shapes their trajectories is gaining increasing attention. In this paper, we analyze current forms and implications of c

The concept of sustainable lifestyles is said to have reached the limits of its usefulness. As commonly understood, it impedes an effective response to our increasingly complex world, and the associated societal challenges. In this context, the emerging paradigm of relationality might offer a way forward to renew our current understanding and approach. We explore this possibility in this study. Fi

Background and Aims: We aimed to compare the risk of frailty in older adults with incident inflammatory bowel disease (IBD) and matched non-IBD comparators and assess the association between frailty and future hospitalizations and mortality. Methods: In a cohort of patients with incident IBD ≥60 years of age from 2007 to 2016 in Sweden identified using nationwide registers, we defined frailty usin

Manipulating light on the nanometer scale is a challenging topic not only from a fundamental point of view, but also for applications aiming toward the design of miniature optical devices. Nanoplasmonics is a rapidly emerging branch of photonics, which offers variable means to manipulate light using surface plasmon excitations on metal nanostructures. As a spectroscopic phenomenon discovered nearl