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Cardiovascular changes in patients with mild-to-moderate chronic kidney disease compared with healthy subjects : a 5-year follow-up study

Background: There is limited knowledge about how cardiovascular parameters change over time in patients with mild-to-moderate chronic kidney disease (CKD). We studied several cardiovascular biomarkers over a 5-year period in patients with mild-to-moderate CKD and in healthy controls. Methods: Fifty-four patients with CKD stages 2–3 and 54 controls were included. The CKD patients were closely monit

Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes : the TEDDY study

Aims/hypothesis: We studied the association of plasma ascorbic acid with the risk of developing islet autoimmunity and type 1 diabetes and examined whether SNPs in vitamin C transport genes modify these associations. Furthermore, we aimed to determine whether the SNPs themselves are associated with the risk of islet autoimmunity or type 1 diabetes. Methods: We used a risk set sampled nested case–c

Outcomes After Surgery for Unilateral Dominant Primary Aldosteronism in Sweden

Background: Primary aldosteronism (PA) is the most common cause of secondary hypertension. Surgery is the mainstay of treatment for unilateral dominant PA, but reported cure rates varies. The aim of the present study was to investigate contemporary follow-up practices and cure rates after surgery for PA in Sweden. Methods: Patients operated for PA and registered in the Scandinavian Quality Registe

Synaptotagmin binding to botulinum neurotoxins

Botulinum neurotoxins (BoNTs) are exceptionally toxic proteins that cause paralysis, but are also extensively used as treatment for various medical conditions. Most BoNTs bind two receptors on neuronal cells, namely a ganglioside and a protein receptor. Differences in the sequence between the protein receptors from different species can impact the binding affinity and toxicity of the BoNTs. Here w

Maternal age and risk of cesarean section in women with induced labor at term—A Nordic register-based study

Introduction: Over the last decades, induction of labor has increased in many countries along with increasing maternal age. We assessed the effects of maternal age and labor induction on cesarean section at term among nulliparous and multiparous women without previous cesarean section. Material and methods: We performed a retrospective national registry-based study from Denmark, Finland, Iceland,

Ingemar Ståhl 1938-2014. A Portrait of a Political Economist in the Swedish Welfare State

For many decades, Ingemar Ståhl was a well-known economist in Sweden. He introduced new perspectives into research, teaching and public debate. He made his presence felt in areas as diverse as housing policy, defense economics, energy policy, financial economics, industrial policy, higher education, union controlled wage earner funds, law and economics, health-care economics and taxation. He advoc

In Pursuit of a Stable Stabilization Policy in Sweden. From the Gold Standard to Inflation Targeting and Beyond

In a historical perspective, the stabilization policy regime in Sweden is in a state of constant change, affected by economic crises, international impulses, domestic politics, and developments in macroeconomic theory. Economists have been deeply involved in this process. The current framework for monetary and fiscal policy, with an independent central bank focusing on inflation targeting, and a r

Does innovation add customer value? How servitization affects performance measurement in innovation

This study contributes to a growing stream of literature on servitization in management accounting. In extension to recent explorations in servitization and management accounting, this paper presents how KPIs in innovation reflect the shift towards servitization. The chosen methodology, participatory action design, gives a unique insight how organizations respond and construct KPIs (key performanc

Is Innovation Out of Control?

The aim of this explorative study is to examine the theorical notions in the business model of innovatin that are influence by use of management control systems (MCS). By means of a systematic literature review, the theoretical contrructs are explored and related to part of the MCS, namely the performance measurement systems (PMS) and the business model of innovation (i.e. innovation input, proces

TREatment of ATopic eczema (TREAT) Registry Taskforce : protocol for a European safety study of dupilumab and other systemic therapies in patients with atopic eczema

Background: A long-term prospective observational safety study is essential to characterize fully the safety profile of systemic immunomodulating therapies for patients with atopic eczema. The TREatment of ATopic eczema (TREAT) Registry Taskforce offers a large platform to conduct such research using national registries that collect the same data using a predefined core dataset. Objectives: To pre

Suppression-induced forgetting diminishes following a delay of either sleep or wake

We investigated the duration of suppression-induced forgetting (SIF), and the extent to which retrieval suppression differs between negative and neutral memories. We further examined if SIF was differently affected by sleep versus wake during the delay interval between retrieval suppression and re-test. Fifty participants first learned to associate neutral words with either neutral or negative ima

Is Innovation out of Control? An Explorative Study in Management Control Systems and the Business Model of Innovation

The aim of this explorative study is to examine the theoretical and empirical notions in the business model of innovation that are influenced by use of management control systems (MCS). By means of a systematic literature review, the theoretical constructs are highlighted and related to the diagnostic and interactive uses of part of the MCS, namely the performance measurement systems (PMS), and thThe aim of this explorative study is to examine the theoretical and empirical notions in the business model of innovation that are influenced by use of management control systems (MCS). By means of a systematic literature review, the theoretical constructs are highlighted and related to the diagnostic and interactive uses of part of the MCS, namely the performance measurement systems (PMS), and th

Students making sense of motion in a vertical roller coaster loop

Describing the motion in a vertical roller coaster loop requires a good understanding of Newton's laws, vectors and energy transformation. This paper describes how first-year students try to make sense of force and acceleration in this example of non-uniform circular motion, which was part of a written exam. In addition to an analysis of the exam solutions by about 60 students, a group interview w

Is innovation out of control?

that are influenced by use of management control systems (MCS). By means of a systematic literature review, the theoretical constructs are explored and related to part of the MCS, namely the performance measurement systems (PMS) and the business model of innovation (i.e. innovation input, process, output, and outcome). The results of the systematic literature review will be used to develop a set o