Diffusion MRI may enable non-invasive mapping of axonal microstructure. Most approaches infer axon diameters from effects of time-dependent diffusion on the diffusion-weighted MR signal by modeling axons as straight cylinders. Axons do not, however, propagate in straight trajectories, and so far the impact of the axonal trajectory on diameter estimation has been insufficiently investigated. Here,

The present paper argues that experimental phenomenology has an important role to play in research on mindfulness. Experimental phenomenology is defined as a subcategory of phenomenology (defined as the science of our subjective experience of being in the world), which explores the effects of intentional variations of subjective experiencing (direction of attention and choice of attitude) on subse

We argue that the two temporal cognition systems are conceptually too confined to be helpful in understanding the evolution of temporal cognition. In fact, we doubt there are two systems. In relation to this, we question that the authors did not describe the results of our planning study on ravens correctly, as this is of consequence to their theory.

This chapter aims to give an overview of the process of interactive model building in macromolecular neutron crystallography for the researcher transitioning from X-ray crystallography alone. The two most popular programs for refinement and model building, phenix.refine and Coot, respectively, are used as examples, and familiarity with the programs is assumed. Some work-arounds currently required

På samma sätt som det är naturligt för ungdomar från bruksorter att flytta till Stockholm bör Stockholmsungdomar ställa in sig på att flytta ut från stan, skriver Ingemar Bengtsson, universitetslektor i fastighetsvetenskap vid Lunds universitet.

Föreläsningen är en märklig undervisningsform. Samtidigt som den är den vanligast förekommandemetoden, är den också den mest föraktade. Det finns gott om högskolepedagogisklitteratur som förklarar varför föreläsningen är olämplig för att stimulera lärande. Ändåfortsätter vi föreläsa. Det kan tyckas motsägelsefullt.Denna reflektion vänder på frågan och letar efter föreläsningens fördelar. Utifrån t

Solid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their ability to store and release organic molecules can be tailored through the identity of the lipids and surfactants used. When stored, polymorphic transitions in the core of drug-loaded SLNs lead to the prematur

Objective Investigating demographic and socioeconomic factors as intersecting rather than as separate dimensions may improve our understanding of the heterogeneous distribution of type 2 diabetes in the population. However, this complexity has scarcely been investigated and we still do not know the accuracy of these factors for predicting type 2 diabetes. Improved understanding of the demographic

The rapid accumulation of ancient human genomes from various areas and time periods potentially enables the expansion of studies of biodiversity, biogeography, forensics, population history, and epidemiology into past populations. However, most ancient DNA (aDNA) data were generated through microarrays designed for modern-day populations, which are known to misrepresent the population structure. P

Background and purpose — The all-polyethylene tibial (APT) component, introduced in the early 1970s, was surpassed by metal-backed tibial (MBT) trays as the first choice for total knee arthroplasty (TKA). With improved polyethylene, the modern APT components can reduce costs, and have shown equivalent results in survivorship and early migration of the cruciate-retaining and cruciate-stabilizing de

Background The mortality in individuals with a family history of heart failure (HF) has not been determined. This nationwide sib-pair study aimed to determine mortality in individuals with a sibling affected with HF. Methods Sib-pairs were linked using the Swedish Multi-Generation Register, the Hospital Discharge Register and the Cause of Death Register for the period 1987–2012. Families with card

Rapporten er utarbeidet i forbindelse med FoU-prosjektet «Virkningene av voldsoffererstatning». Prosjektet har hatt som formål å gi økt kunnskap om virkninger, i betydning av bruker- og samfunnseffektene av voldsoffererstatningen.Oppdraget er gjennomført av Oxford Research. Prosjektleder har vært sjefanalytiker Tor Egil Viblemo ved Oxford Research og prosjektdeltakerne har vært Vegard Solhjem Knut

Introduction Half of all Ugandans (49%) turn to the private or private-not-for-profit (PNFP) sectors when faced with illness, yet little is known about the capacity of these sectors to deliver surgical services. We partnered with the Ministry of Health to conduct a nationwide mixed-methods evaluation of private and PNFP surgical capacity in Uganda. Methods A standardized validated facility assessm

I kapitlet resoneras utifrån ett rättssociologiskt perspektiv, kring vilka möjligheter barnkonventionen som lag har att förändra yrkesverksammas arbete i praktiken, med poliser som exempel. Poliser kan, liksom flera andra offentligt anställda tjänstepersoner, ses som ”gräsrotsbyråkrater” vars handlingsutrymme påverkas och styrs av en mängd andra faktorer förutom lagstiftning. I kapitlet diskuteras

Higher Education in the European context has been transformed radically since 1990s, partly in line with global political and economic trends. In the Swedish context these trends also manifested itself, among other things, in how teaching is practiced and valued. The managerial and paradigmatic shift altered the balance between teaching and research in the favour of the latter. This happened while

I denna rapport redovisas populationstrender för 212 svenska fågelarter för olika långa tidsperioder. Fåglarna har räknats vinter, vår och sommar enligt strikt standardiserade metoder. Sommar- respektive vinterpunktrutter har räknats sedan 1975, i huvudsak i södra Sverige. Standardrutterna räknas också på sommaren (sedan 1996) men täcker hela Sverige på ett representativt sätt. Nattaktiva fåglar h

In Parkinson's disease, the degeneration of dopaminergic neurons in substantia nigra leads to a decrease in the physiological levels of dopamine in striatum. The existing dopaminergic therapies effectively alleviate the symptoms, albeit they do not revert the disease progression and result in significant adverse effects. Transplanting dopaminergic neurons derived from stem cells could restore dopa