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Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a key regulator of metabolism, but how its structural dynamics control allosteric signaling remains unclear. To investigate this, we performed molecular dynamics simulations of PPAR-gamma and applied time-lagged independent component analysis to reduce the dimensionality of the data. Microstates were identified using K-means clusteri

Approximately 80% of agricultural land in the world is comprised of annual crops which have a life span of only one year. Research has shown that these crops are unsustainable because of these short life spans. Soil erosion, nutrient leaching, and losses of soil carbon are just a few problems caused by annual monocultures. Additionally, with the changing climate, these cropping methods are both vu

This thesis examines how Kenyan Generation Z activists used social media, particularly X (Twitter) as a tool for resistance, mobilization, and political discourse during the 2024 protests against the Finance Bill. Drawing on a postcolonial Global Studies framework, the study situates Kenya’s digital protests within broader global systems of inequality, colonial legacy, and youth disenfranchisement

Equity Real Estate Investment Trusts (REITs) face persistent challenges in performance tracking and financial reporting due to fragmented data systems, manual processes, and delayed access to critical insights. This thesis examines the use of Power BI, a business intelligence (BI) tool, as a means to modernize reporting practices and support data-driven decision-making within REITs. Drawing on use

Background: Type 2 diabetes (T2D) and dementia represent a growing dual burden in aging populations. These conditions share pathophysiological mechanisms that may create a self-reinforcing cycle in which cognitive impairment affects diabetes management, a crucial factor for preventing complications. Despite Sweden's comprehensive care, there is limited longitudinal evidence on how cognitive

Work passion is increasingly regarded as essential for both organizational success and individual well-being, yet its antecedents and underlying mechanisms remain underexplored. This study investigates how workplace factors (job autonomy, procedural justice, and leader– member exchange) relate to harmonious and obsessive passion through the mediating role of psychological need satisfaction. A cros

The design and development of drugs which can permeate the blood brain barrier (BBB) for the treatment of hard-to-treat central nervous system (CNS) diseases is a critical and prevalent challenge in medicinal chemistry. Such diseases include Alzheimer’s Disease (AD) and Parkinson’s Disease (PD) - both chronic and progressive neurodegenerative disorders affecting the brain. Galectin-3 (gal-3) is a

Galectins are small, carbohydrate-binding proteins widely distributed among different cells and tissues in the human body. Due to their abundance, these proteins are involved in many processes and diseases. Among the different types of galectins found in the human body, galectin-1 and galectin-3 are the most common, thus the most targeted and studied. Particularly, galectin-3 is the only chimeric

This thesis investigates whether intermediate and advanced Swedish learners of Japanese language can use prosodic cues—particularly pitch-based features such as downstep—to differentiate between structurally ambiguous noun phrases, specifically those having both left branching (LB) and right branching (RB) interpretations, in spoken Japanese in the same way as native speakers. It also examines

Hälso- och sjukvården påverkar dagens miljö och som operationssjuksköterska med användning av olika kirurgiska instrument såsom engångs-, flergångs och hybridinstrument samt material. Instrument packas upp, används och antingen slängs i onödan eller behöver gå tillbaka till steriliseringsprocessen. Operationssjuksköterskan bör vara medveten om kirurgiska instruments miljöpåverkan, resursförbruknin

This thesis explores how disaster-affected communities in the Kavre and Bardiya districts of Nepal perceive and experience cash assistance projects. The research was guided by two core questions: (1) What are community members' perceptions and preferences of cash assistance in disaster affected areas in the Kavre and Bardiya districts of Nepal? (2) How could these community perceptions and pre

Denna kandidatuppsats utforskar hur vardagliga användare, specifikt icke-experter inom högre utbildning, interagerar med AI-baserade chattbottar genom naturliga språkprompter. Tidigare forskning har främst fokuserat på att förbättra modellernas prestanda och förstå promptmekanismer, men har i liten utsträckning uppmärksammat hur användare utan teknisk expertis upplever och formar dessa interaktionThis bachelor’s thesis explores how everyday users, specifically non-experts in higher education, interact with AI-based chatbots through natural language prompts. While prior research has focused on improving model performance and understanding prompt mechanics, little attention has been given to how users without technical expertise experience and shape these interactions. The study aimed to exp

Hur s ag universum ut bara n agra o ̈gonblick efter Big Bang? Det är en av de mest spännande frågorna inom fysiken i dag. Under denna ursprungliga tid bestod universum av ett extremt hett och tätt tillstånd av materia. Detta tillstånd existerar inte naturligt, dock har forskare lyckats ̊aterskapa det i laboratorier med hjälp av kollisioner av tunga atomkärnor. Detta tillstånd kallas kvark-gluonplaHow do event-by-event temperature fluctuations in the quark–gluon plasma alter jet- quenching signatures? This thesis answered that question by using the simulation tool JEWEL with two different medium models. The first one was a more realistic, event-by- event ”lumpy” temperature profile in the plasma. The second one treated the medium as a smooth, average background instead. Jet quenching is the

The bachelor’s thesis explores end-customers’ perceptions regarding the differences between AI-based and human customer service, and the interaction factors that influence their experi-ences. With a focus on customer satisfaction and perceived problem-solving, the study aims at providing recommendations for the development and design of AI chatbots to better meet customer expectations and satisfac

The introduction of private label brands (PLBs) have transformed the landscape of grocery retail, challenging the dominance of manufacturer brands (MBs) and redrawing the lines of in-store competition. As shelf space plays a critical role in shaping consumer behavior at the point of purchase, this study investigates whether Swedish grocery retailers allocate shelf space to PLBs in ways that exceed

Monitoring of human motion classification provides several opportunities to aid the process of rehabilitation, exercise logging and much more. In this thesis, Inertial Measurement Unit (IMU) devices positioned on different body parts are used to collect accelerometer and gyroscope data. This data is then combined to predict what gym exercise is being performed by the user. Different architectures

This thesis examines how public discourse in Nigeria reflects the drivers behind Bitcoin adoption. Using thematic analysis of Nigerian newspaper articles from 2020 to 2025, the study identifies three key themes: economic instability, political resistance, and financial inclusion. Through the lens of Austrian economic theory, especially Hayek’s idea of currency competition, Bitcoin adoption is inte

Following the discontinuation of LIBOR, the interest rate market has transitioned to backward-looking benchmarks such as SOFR. Unlike traditional forward-looking rates like LIBOR, SOFR is set in arrears, which affects the pricing methods of derivatives linked to these benchmarks. This thesis studies the impact of this transition on the pricing and calibration of caps within the Hull-White framewor

Föreliggande examensarbete ämnar belysa och problematisera lyssneläsningsbegreppet utifrån den mediala debatten i Svenska Dagbladet och genom intervjuer av tre specialpedagoger och tre svensklärare på gymnasial nivå. Syftet innefattar att lyfta fram olika erfarenheter och framställningar av lyssneläsning med tematisk ingång för att sedan diskutera möjliga didaktiska implikationer. Resultaten visarThis study aims to illuminate and problematize the concept of listening-while-reading based on the media debate in Svenska Dagbladet and through interviews with three special needs education teachers and three Swedish teachers at upper secondary level. Through thematic analysis of both articles and interviews themes of experiences and perceptions about listening-while-reading can be highlighted an