Structural and Functional Studies on Posttranslational Modifications of Collagen type II in Rheumatoid Arthritis.
The molecular mechanisms behind the development and progression of rheumatoid arthritis are not known in fine details. Both humoral and cellular responses against collagen type II in joint cartilage seems to be important for the disease development. Especially posttranslational modifications on collagen type II are important in regulation of molecular mechanisms implicated in the disease. In this
