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‘Wet’ eldercare facilities: three strategies on the use of alcohol and illicit substances

Wet eldercare facilities constitute a type of harm reduction arrangements where goals of abstinence are abandoned in favour of goals of increased wellbeing for older people with long-term substance use disorder. The fact that residents are acknowledged as being active in their substance use results in challenges; harmful activities are witnessed by the staff in a context that has actually been cre

Antigen restriction and IgG subclasses among anti-GBM autoantibodies

Thirty-seven sera positive for anti-GBM antibodies (antibodies against the ‘Goodpasture antigen’ = NCI-domain of collagen IV) in routine analysis were studied for antigen restriction and IgG subclasses. Four different polypeptides, the four α-chains (α1, α2, α3 and α4) of human collagen IV NCI, were used as coating in ELISA assays. Autoantibodies were detected with monoclonal antibodies towards hu

Pd-LaFeO3 Catalysts in Aqueous Ethanol : Pd Reduction, Leaching, and Structural Transformations in the Presence of a Base

The reactive behavior of three catalysts based on Pd-loaded LaFeO3 was investigated in terms of the reducibility of Pd and its propensity to leaching into the liquid phase in flowing solutions prototypical of C-C coupling catalysis in a continuous flow reactor cell. In situ quick extended X-ray absorption fine structure spectroscopy showed that Pd remains stable and nonreducible in the flowing eth

Evaluating Clusters : Where Theory Collides with Practice

Cluster policies are widely used to strengthen regional competitiveness, yet difficult to evaluate. While academic approaches to cluster evaluation are often ignorant of the needs of policy-makers and practitioners, practitioner-led approaches often lack structure and rigour. As such, there remain significant gaps between theory and practice. The contribution of this paper is to reflect on a uniqu

Influence of wind conditions and intertrap spacing on pheromone trap catches of male European pine sawfly, Neodiprion sertifer

The spatial distribution of catches of male European pine sawfly, Neodiprion sertifer (Geoffr.) (Hymenoptera, Diprionidae), was studied using different pheromone trap arrays. In hexagonal trap groups, trap interference was evident by reduced catch in the central of seven traps spaced 10 to 40 m apart. When the trap spacings were either 5 or 80 m no significant reduction could be shown. The interac

Poor academic performance in offspring of survivors with childhood or adolescent central nervous system tumor in Sweden

The number of children who were born after their parents were diagnosed with central nervous system (CNS) tumor is increasing, but it remains largely unknown regarding the academic performance of these children. We aimed to investigate whether children of survivors with childhood or adolescent CNS tumor were associated with poor academic performance. Children of survivors of CNS tumor were identif

Do negative intrusive thoughts at diagnosis predict impaired quality of life, depressed mood and waking up with anxiety 3, 12 and 24 months after radical prostatectomy?–a longitudinal study

Objective: To evaluate the effect of intrusive thoughts at diagnosis on quality of life, depressed mood and waking up with anxiety up to two years after radical prostatectomy. Method: The Laparoscopic Prostatectomy Robot Open (LAPPRO) trial was a prospective, longitudinal multicenter study of 4003 patients undergoing radical prostatectomy. Questionnaire data were collected preoperatively, at 3, 12

Comparison of heat losses at the impingement point and in between two impingement points in a diesel engine using phosphor thermometry

In-cylinder heat losses in diesel engines reduce engine efficiency significantly and account for a considerable amount of injected fuel energy. A great part of the heat losses during diesel combustion presumably arises from the impingement of the flame. The present study compares the heat losses at the point where the flame impinges onto the piston bowl wall and the heat losses between two impinge

Optimal Trade-Off Between Economic Activity and Health During an Epidemic

Thispaperconsidersasimplemodelwhereasocialplannercaninfluencethespread-intensity of an infection wave, and, consequently, also the economic activity and population health, throughasingleparameter. Populationhealthisassumedtoonlybenegativelyaffectedwhen thenumberofsimultaneouslyinfectedexceedshealthcarecapacity. Themainfindingisthat if (i) the planner attaches a positive weight on economic activity a

Mitochondrial dysfunction and calcium dysregulation in leigh syndrome induced pluripotent stem cell derived neurons

Leigh syndrome (LS) is the most frequent infantile mitochondrial disorder (MD) and is characterized by neurodegeneration and astrogliosis in the basal ganglia or the brain stem. At present, there is no cure or treatment for this disease, partly due to scarcity of LS models. Current models generally fail to recapitulate important traits of the disease. Therefore, there is an urgent need to develop

ANCA and IgG subclasses

We studied IgG subclass distribution of ANCA in 247 patients with ELISA. We used monoclonal subclass specific antibodies and purified MPO and proteinase 3 as antigen. We found that IgG1 and IgG4 yield high values in both groups. We also found that high IgG2 titers were rare among the anti-proteinase 3 positive, while it was common among anti-MPO sera. In the assays for IgG3 the situation was the o

Screening for anti-neutrophil cytoplasmic antibodies (ANCA) : Is indirect immunofluorescence the method of choice?

Detection of ANCA has become an important tool for the diagnosis and monitoring of disease activity in Wegener's granulomatosis (WG). Unfortunately, a group of sera positive by the standard method for ANCA detection, indirect immunofluorescence (IIF), are negative when more specific tests with purified proteins are used. In order to examine this discrepancy we examined groups of sera selected for

Space and practices : Engagement of children under 3 with tablets and televisions in homes in Spain, Sweden and England

Young children’s engagements with digital technologies form part of their emergent everyday literacy practices. The study reported here derives from the pan-European study ‘A Day in the Digital Lives of Children aged 0-3’. The methodology was centred on the videoing of an entire day’s experiences of a child aged under 3, together with a reflective interview with the parents and inventories related

Events and Causal Mappings Modeled in Conceptual Spaces

The aim of the article is to present a model of causal relations that is based on what is known about human causal reasoning and that forms guidelines for implementations in robots. I argue for two theses concerning human cognition. The first is that human causal cognition, in contrast to that of other animals, is based on the understanding of the forces that are involved. The second thesis is tha