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Dwell time is crucial for railway operations, for example, 20% of the total travel time in a mass transit context in the Paris region. With this, it is also a source of delays due to its variability. One way to ensure the robustness of a timetable is to add margins as buffer time that can be consumed to absorb short delays. Much work has been done on run time margins, but dwell time margins receiv

There can be situations, for example if gas containers have been damaged in a vehicle crash, when the fire and rescue service would like to depressurize the gas containers through shooting with a civilian rifle. Modern high-pressure hydrogen containers are designed for a working pressure of 700 bars. This means that they have a very thick and strong shell made of composite material. At the same ti

BACKGROUND: Attention Deficit Hyperactivity Disorder (ADHD) is a commonly occurring neurodevelopmental disorder associated with impairments in numerous aspects of functioning and quality of life. There is a growing recognition that brief and effective psychosocial interventions are needed for youth with ADHD.OBJECTIVE: The aim of this study was to assess the feasibility and preliminary effectivene

PurposeThe purpose is to increase the understanding of when a heritage in the non-profit category becomes a part of the established heritage sector, and how this can be understood with regard to the rising awareness of climate change in heritage management and recent theories within the field. The case is Hindås Ski Jumping Hill in Hindås, Sweden, which since 2022 is a listed building in Sweden.De

This article is based on the creation of sports heritage as having strong roots in the Anthropocene. It particularly discusses listed building declarations of the built heritage of sport, from a Swedish perspective, as well as the feelings of nostalgia associated with such activities. Two contemporary examples of preserved sports heritage sites, Hindås Ski Jumping Hill in Hindås and the stand at V

Nutrients are the lifeblood of aquatic ecosystems, but not all nutrients are equally accessible to the organisms that depend on them. While traditional monitoring often tracks total or inorganic concentrations of carbon, nitrogen, and phosphorus, these measures do not reflect what microbial communities can actually use. This thesis explores that disconnect by investigating the bioavailability of k

BACKGROUND: Exertional breathlessness is a major symptom in cardiorespiratory disease and is often assessed using the modified Medical Research Council (mMRC) questionnaire. The mMRC might underestimate exertional breathlessness in people with impaired exercise capacity who have reduced their physical activity to avoid the symptom. We aimed to evaluate the ability of mMRC to detect abnormally high

The plasma proteome is maintained by the influx and efflux of proteins from surrounding organs and cells. To quantify the extent to which different organs and cells impact the plasma proteome in healthy and diseased conditions, we developed a mass-spectrometry-based proteomics strategy to infer the tissue origin of proteins detected in human plasma. We first constructed an extensive human proteome

Surgical systems are complex and susceptible to external system pressures. The SARS-CoV-2 pandemic and its impact on elective surgery illustrated this. The reassignment of resources to the acute care of patients with COVID-19 led to cancellations of elective services that varied according to surges of the pandemic. Overall, it was estimated that more than 28 million operations were cancelled or po

Background: The occupational therapy intervention Balancing Everyday Life (BEL)TM aims to support mental health service users towards improved occupational balance and personal recovery. Yet, no research has specifically addressed recovery experiences among BELTM participants. Aim: To investigate how the recovery process was experienced by mental health services users who had participated in BELTM

Objectives: In this nationwide cohort study in a Scandinavian setting, we aimed to investigate the magnitude of association between flucloxacillin use and drug-induced liver injury (DILI). Methods: Nationwide cohort study among adults in Sweden, 2006–2018, was conducted. Register data on filled prescriptions, patient characteristics, co-medications, and DILI were linked. All filled prescriptions f

Background: COVID-19 caused a profound global impact, resulting in significant cases and deaths. The progression of COVID-19 clinical manifestations is influenced by a dysregulated inflammatory response. Early identification of the subclinical progression is crucial for timely intervention and improved patient outcomes. While there are various biomarkers to predict disease severity and outcomes, t

Background: Extended reality (XR), encompassing technologies such as virtual reality, augmented reality, and mixed reality, has rapidly gained prominence in health care. However, existing XR research often lacks rigor, proper controls, and standardization. Objective: To address this and to enhance the transparency and quality of reporting in early-phase clinical evaluations of XR applications, we

Health is multifaceted, with divergent interpretations in diverse cultures and groups of individuals. The ways individuals understand health might aid in developing future interventions. There is scant knowledge on how adolescents with depression conceptualise health. A descriptive qualitative design with a phenomenographic approach was used to describe the different ways adolescents with depressi

Denna studie undersöker hur restid upplevs och används av kollektivtrafikresenärer. Genom en enkät med drygt tusen respondenter och samtal i en fokusgrupp framkommer flera intressanta insikter.Mobiltelefonen har blivit den mest använda utrustningen ombord, medan traditionella medier som böcker och tidningar har minskat i förekomst. Vanliga aktiviteter under resan inkluderar att scrolla på mobilen,This study examines how travel time is perceived and utilised by public transport passengers. Through a survey of just over a thousand respondents and discussions in a focus group, several interesting insights emerge.The mobile phone has become the most used device on board, while traditional media such as books and newspapers have decreased in prevalence. Common activities during the journey incl

INTRODUCTION: The generalizability of neuroimaging and cognitive biomarkers in their sensitivity to detect preclinical Alzheimer's disease (AD) and power to predict progression in large, multisite cohorts remains unclear. METHOD: Longitudinal demographics, T1-weighted magnetic resonance imaging (MRI), and cognitive scores of 3036 cognitively unimpaired (CU) older adults (amyloid beta [Aβ]-negative