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Acute myeloid leukaemia (AML) is a highly aggressive type of blood cancer. In particular, elderly and medically unfit patients face a poor prognosis. Treatment with venetoclax and azacitidine improved the outcome for these patients, yet drug resistance remains a significant issue. Combining the poly (ADP-ribose) polymerase (PARP)1/2 inhibitor talazoparib with venetoclax and azacitidine was suggest
The concept of servitization has brought about a significant transformation in numerous industries, signaling a strategic shift from a focus on goods to a service-oriented perspective. With the ascent of “Games as a Service”, Service-dominant logic is highly relevant in understanding games as a service. where players emerge as co-creators of value, shaping their unique experiences and meaning in t
The aim of this thesis is to illuminate, from a Catholic view, the role of different ethical theories in the formulations of, and proposed solutions to, the problem of evil. More specifically, what happens to the problem when applying a Catholic ethic, à la the moral theologian Germain Grisez, to God is examined. This is done by first analyzing which ethical assumptions lie behind the various form
Danielsson, F. 2023. Rya gamla kyrka: A study about the relation between landscape and church in Rya parish. Medieval churches have been a key part of the research field of historical archaeology in Lund since its beginning. In recent years there have been an increasing interest in studying the relationship between early church construction and the landscape in which they were formed. This study a
This thesis examines the effectiveness of macroprudential borrower-based measures such as loan-to-value caps and amortization requirements on household financial resilience represented by debt, savings, and real-house prices in Sweden. The model that is used is a Structural Vector autoregressive (SVAR) with a forecasted error decomposition to expand on the current literature on the subject wit
Bakom den pågående klimatkrisen, hoten mot den biologiska mångfalden, miljöförstöringen och nedsmutsningen av våra hav finns samma orsak: den ohållbara resursanvändningen i dagens produktion och konsumtion. Nuvarande resursanvändning bidrar till 90% av förlusten av biologisk mångfald och 50% av klimatpåverkan. En cirkulär ekonomi kan bidra till att minska resursanvändningens omfattande miljöpåverkThe major driver of the climate and biodiversity crisis is our unsustainable production and consumption patterns, but the need to transition to a circular and resource-efficient economy has not been sufficiently addressed by policymakers. Policies supporting circular industrial transition are still rare, not the least in contrast with the recent momentum gained by green industrial policy in EU and
The purpose of this thesis was to investigate whether video object detection methods can outperform single-frame object detection methods in the context of maritime navigation. Object detection is a well-explored area within machine learning with many high performing published methods. Video object detection however, where information from previous video frames is considered in order to capture hi
Northern peatlands, spanning across vast regions of the northern hemisphere, are critical carbon reservoirs essential for global carbon cycling and climate regulation. Their dual role as long-term atmospheric carbon dioxide (CO2) sinks and the largest natural source of methane (CH4) in the northern hemisphere allows them to accumulate more carbon than they emit, helping to mitigate the rise in atm
Grass pollen allergies caused by Timothy grass affect the lives of many people and have a huge economic impact on our society. Hypersensitivity reactions are triggered by allergens and allergen-specific IgE, leading to degranulation of mast cells releasing bioactive compounds causing allergic symptoms. Improvement of allergen-specific immunotherapy (AIT) involving gradual exposure to the allergen
Denna uppsats har genom en analys av estetikern Hans Ruins poesibegrepp poesiens mystik, på samma gång genomfört en processartad estetisk-teologisk metodutveckling av Dorthe Jørgensens erfarenhetsmetafysik in spe, genom att tillfoga den, och samtidigt begreppsutveckla, passagen som en plats för förflyttning och förvandling. Uppsatsen bygger på en estetisk-teologisk teori om det sköna tänkandet soIn this thesis, titled "som förvandlande passage", "as transforming passage", I investigate the Finland-Swedish aesthetician Hans Ruin ́s concept of poetry as "poesiens mystik", "the mysticism of poetry". The essential aim of the thesis is both to reach a deeper analysis and understanding of Ruin ́s concept of poetry and, through this and through adding the
Artificiell intelligens används för att känna igen detaljerade vägnätverk med hjälp av flygfotografi och data från OpenStreetMap. Modellen kan känna replikera körfiler och deras riktning, men inte alltid hur dessa ansluter vid korsningar. Utmaningen med att skapa detaljerade kartor Att ha tillgång till detaljerade och korrekta digitala kartor över transportnätverk är avgörande för områden som navAccess to detailed network data is often constrained by access-controlled datasets or by extensive manual labour. This study addresses the challenge by proposing a novel approach to extract lane-level road topology graphs at signalised intersections. The aim is to predict intersection topologies directly from aerial imagery and a simplified OpenStreetMap road-level graph using neural networks, bri
Machine learning models can analyze physiological data, such as electroencephalography (EEG), for various classification tasks. One such task is Auditory Attention Decoding (AAD), aimed at identifying the sound a person is actively attending to, offering significant benefits for users of hearing aids. However, EEG data often exhibits a low signal-to-noise ratio, and its collection is often expensi
In this thesis general formulas for calculating variance and total variance for the dynamics of distributed averaging in discrete time are presented. These formulas are derived by building on previous notions and ideas of stability measures and convergence. In doing so, a framework for quantifying stability of distributed averaging models through variance and total variance is provided. In additio
Oh dear god, how can something so simple become this hard? It’s just a house, I’ve lived in houses before, my entire life actually. But now I’m the one who’s designing it, for me and my family. All of a sudden, this fundamental thing of living and creating a home gets all rusty with the patina of pressure. I can’t oversee anything, I can’t take things for granted. Now, it’s time to decide, or shou
The Atlantic Multidecadal Variability (AMV) is a variation in sea surface temperature (SST) in the North Atlantic with a period of about 60-90 years. The drivers of this mode of variability are largely unknown as observational data only go back 150 years. Global climate models can help us better understand the AMV and its drivers and this thesis investigates how the AMV behaves in the Earth system
This thesis studies how subject extractions are accepted in Scandinavian (Danish, Norwegian, Swedish and Fenno-Swedish) through an extensive acceptability judgment study. The results from the study were compared with previous research and analyzed against accounts on why subject extraction constraints occur and why the acceptance of subject extractions in Scandinavian vasty varies. The subject ext
Inom algebra finns det ett koncept som heter kohomologi. Från början kom det från topologi: till ett rum kan man associera en mängd algebraiska strukturer, nämligen kohomologigrupperna av rummet, som berättar om vissa egenskaper rummet har. Man märkte relativt snabbt att sådana strukturer kunde användas i fler situationer, och på så vis föddes ämnet homologisk algebra. Det man såg var att man kundWe provide an introduction to the basic theory of triangulated categories and t-structures, and cover these in detail with a particular focus on recollements, roughly speaking gluings. Triangulated categories are a convenient setting for developing foundational results in homotopical algebra, and t-structures allow a refinement of this by imposing that objects have a kind of "grading" on
