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In lung adenocarcinoma, the mutational spectrum is dominated by EGFR and KRAS mutations. Improved knowledge about genomic and transcriptional alterations in and between mutation-defined subgroups may identify genes involved in disease development or progression.
The P blood group antigen of the GLOB system is a glycolipid structure, also known as globoside, on the red blood cells (RBCs) of almost all individuals worldwide. The P antigen is intimately related to the Pk and NOR antigens discussed in the review about the P1PK blood group system. Naturally occurring anti-P is present in the serum of individuals with the rare globoside-deficient phenotypes p,
BACKGROUND: The character higher order scales (self-directedness, cooperativeness, and self-transcendence) in the temperament and character inventory are important general measures of health and well-being [Mens Sana Monograph 11:16-24 (2013)]. Recent research has found suggestive evidence of common environmental influence on the development of these character traits during adolescence. The pres
OBJECTIVE: To evaluate the effects of intrauterine growth restriction (IUGR) with absent or reversed end-diastolic blood flow in the umbilical artery and very preterm birth on cognitive outcome at 5 to 8 years of age. METHODS: We studied 34 children with IUGR born at a median of 26.9 gestational weeks (GWs) (range: 24-29 GWs) (PT-IUGR), 34 matched preterm appropriate-for-gestational age (PT-AGA) c
Fractures of the distal radius in postmenopausal women may cause prolonged pain and disability, but little is known about their natural course beyond the first year. In this study, women of 50-75 years of age, initially treated with cast or external fixation, were examined 1 year after distal radial fracture and then re-evaluated after a mean of 3 (range, 2-4) years. The evaluation included pain,
This Letter reports a measurement of the W W production cross section in root s = 7 TeV pp collisions using data corresponding to an integrated luminosity of 1.02 fb(-1) collected with the ATLAS detector. Using leptonic decays of oppositely charged W bosons, the total measured cross section is sigma (pp -> W W) = 54.4 +/- 4.0 (stat.) +/- 3.9 (syst.) +/- 2.0 (lumi.) pb, consistent with the Standard
Among heavy-fermion metals, Ce3Pd20Si6 is one of the heaviest-electron systems known to date. Here we used high-resolution neutron spectroscopy to observe low-energy magnetic scattering from a single crystal of this compound in the paramagnetic state. We investigated its temperature dependence and distribution in momentum space, which was not accessible in earlier measurements on polycrystalline s
In normal cells, the cell cycle is controlled by a complex series of signalling pathways by which a cell grows, replicates its DNA and divides. The critical task of the cell cycle is to ensure that DNA is faithfully replicated and that identical chromosomal copies are distributed equally to two daughter cells during mitosis with the help of the mitotic spindle. Thus, mitotic spindle formation is v
This paper examines vowel-to-vowel lingual coarticulation in sequences of vowel-bilabial consonant-vowel, where the duration of the oral closure for the consonant is either long or short. Native speakers of Japanese served as subjects. The linguistic material consisted of Japanese word pairs that only differed in the duration of the labial consonant, which was either long or short. Recordings were
Using a combined experimental and theoretical approach, we show that a thin RhO2 oxide film forms on a Pt25Rh75(100) surface at elevated oxygen pressures and temperatures prior to the bulk oxidation. By the use of in situ surface x-ray diffraction under realistic CO oxidation reaction conditions, we show that the onset of the growth of thin RhO2 oxide film coincides with an increase in CO2 product
The purpose of this article is to describe generally usable methods to measure the sound insulation of a facade in cases where a setup according to standards such as ISO 140/5 or ISO 16283/3 cannot be achieved. The methods discussed use a loudspeaker as the source of a test signal since background noise on the interior receiving side in many cases prevents the use of traffic as a noise source. The
Background: The production of bioethanol from lignocellulose hydrolysates requires a robust, D-xylose-fermenting and inhibitor-tolerant microorganism as catalyst. The purpose of the present work was to develop such a strain from a prime industrial yeast strain, Ethanol Red, used for bioethanol production. Results: An expression cassette containing 13 genes including Clostridium phytofermentans Xyl
Direct electron transfer (DET) from bare spectrographic graphite (SPGE) or 3-mercaptopropionic acid-modified gold (MPA-gold) electrodes to Trachyderma tsunodae bilirubin oxidase (BOD) was studied under anaerobic and aerobic conditions by cyclic voltammetry and chronoamperometry. On cyclic voltammograms nonturnover Faradaic signals with midpoint potentials of about 700 mV and 400 mV were clearly ob
This Paper Presents a method to characterize the pore structure of the fibre surface for the honeycomb-patterned PET fibers; by using scanning electron microscopy (SEM) and image processing techniques. They consist of linear channel pores (LCP) and ellipse pores The surface pore distribution and micro pore numbers varied from each fiber to another, which can make significant differences on the. pr
The paper is aimed at the identification and characterization of wear mechanisms of SiC whisker-reinforced alumina when turning aged Alloy 718 under different cutting conditions and when machining dry and with coolant. Secondary and backscatter electron microscopy accompanied by focus ion beam milling and EDX techniques were used for analysis of worn-out tools. Notch wear on the major cutting edge
