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Triple-negative breast cancer (TNBC) is a heterogeneous subgroup of breast cancer with poor prognosis and no targeted therapy available. Receptor tyrosine kinases (RTKs) are emerging targets in anticancer therapy and many RTK-inhibiting drugs are currently being developed. The aim of this study was to elucidate if there is a correlation between the protein expression of three RTKs c-KIT, VEGFR2 an

A method for probing the temporal evolution of ultra-fast carrier generation and recombination processes in wide-bandgap semiconductors, e.g. diamond, is described. Two extreme ultraviolet (pump) pulses produced by high-order harmonic generation in Argon gas (with a photon energy of 32 eV) are superimposed on a sample with a small angle between them, inducing periodic changes in the refractive ind

This review study is a first attempt to map the state of entrepreneurship research in China by focusing on the contributions of Chinese researchers. Leading contributors, research collaboration and theoretical underpinnings in both domestic-oriented and international-oriented research are discussed. The review comprises 508 articles published in domestic Chinese journals indexed by the Chinese Soc

The increased availability of digital spatial data combined with improved capabilities of Geographic Information Systems (GIS) have allowed for the development of several global population distribution databases, such as the GPW, and LandScan. Making population distribution data available as a high-resolution raster database which facilitates rapid GIS analysis at the local level and for any zo

A list of 120 taxa observed at the Vadstena Monastery churchyard includes some rare species and a few lichenicolous fungi. Lecanora semipallida is reported from the province Östergötland [Ostrogothia] for the first time.

Here we describe our attempts to study the interaction of nanomodified surfaces with neurons and macrophages. Surfaces with nano-sized topographies produced by UV lithography, electrochemical etching, nanoimprint lithography, microdispensing, or by electrospinning of plastic nanofibers or by making plastic replicas of the extracellular matrix with nanoresolution were found to guide neurite outgrow

A review of the current evidence for internal fixation versus hemiarthroplasty versus primary total hip arthroplasty for displaced femoral neck fractures was undertaken. At the meta-analysis level no difference in postoperative pain, function, or quality of life can yet be demonstrated. A significant difference in mortality has also not been found, but a trend towards higher mortality after primar

Recently, the effect of exposure to persistent organic pollutants (POPs) on sperm concentration was only seen in men with a short androgen receptor (AR) gene CAG repeat. In order to investigate whether these effects could be observed also in vitro, we tested the impact of 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153) and 1,1-bis-(4-chlorophenyl)-2,2-dichloroethene (4,4'-DDE) on 5α-dihydrotestosteron

We present how dramatically the nonequilibrium nature of an oppsitely charged polyelectrolyte/surfactant mixture can affect the interfacial properties. We show for the first time that the cliff edge peak in the surface tension of the poly(diallydimethylammonium chloride)/sodium dodecyl surfate system is produced as a direct result of depletion of surface-active material from the bulk solution due

Lactoperoxidase (LPO) is an enzyme, which is used as an antimicrobial agent in a number of applications, e.g., food technology. In the majority of applications LPO is added to a homogeneous product phase or immobilised on product surface. In the latter case, however, the measurements of LPO activity are seldom reported. In this paperwe have assessed LPO enzymatic activity on bare and protein modif

Exercise during pregnancy is associated with health benefits for both the mother and the fetus, and is therefore recommended in several national guidelines. Only few studies investigate whether these guideline recommendations are met. The aims of this study were 1. To assess the prevalence of pregnant women meeting the Danish recommendations for exercise during early pregnancy, 2. To identify pre-

Hemolytic uremic syndrome, a life-threatening disease often accompanied by acute renal failure, usually occurs after gastrointestinal infection with Shiga toxin 2 (Stx2)-producing Escherichia coli. Stx2 binds to the glycosphingolipid globotriaosylceramide receptor, expressed by renal epithelial cells, and triggers apoptosis by activating the apoptotic factor Bax. Signaling via the ouabain/Na,K-ATP

This article deals with the Finnish-Swedish, Jewish composer and author Moses Pergament and his relationship with Wagner's theories, anti-Semitism in particular, and their influence on the development of modern Swedish classical music during the interwar period. The author emphasizes the importance of recognizing that Pergament's reaction to Wagner's cultural theories was part and parcel of his st

The aim of this article is to offer an object lesson in how historians could make use of feature film as primary source material if they were to use the analytical tools developed in the field of film studies and by historians who started to work with film in the 1970s and 1980s. My own work on representations of maidservants in Swedish feature films in the 1930s and 1940s is used as a case in poi

Before wood ash can be used as a soil fertilizer, concentrations of environmentally hazardous compounds must be investigated. In this study, total and leachable concentrations of 16 polycyclic aromatic hydrocarbons (PAHs) were determined in four ash samples and one green liquor sludge. The ash sample with the highest carbon content also contained high levels of PAHs; three of the ash samples had t

Based on an interview with a hip-hop artist from Eastern Poland, this article critically assesses amateur art pro-duction proliferating throughout the globe today through individuals’ creative usages of new ICTs and new media affordances. The post-Fordist material and ideological context of contemporary social life is the main focus point of the article’s critique. Scarcity, dispossession, and ent

The castes of social insects provide outstanding opportunities to address the causes and consequences of evolution of discrete phenotypes, i.e., polymorphisms. Here we focus on recently described patterns of a positive association between the degree of caste-specific gene expression and the rate of sequence evolution. We outline how neutral and adaptive evolution can cause genes that are morph-bia

The authors present a very interesting data set on the acceleration effects on sheet flow transport and compare their experimental results with different transport practical formulas. However, they omit some previous work by Camenen and Larson (2007) that we would like to bring to the authors' attention. A more extensive discussion on some aspects of the acceleration effects is also lacking in the

Popular Abstract in English This doctoral thesis investigates the onset of cardiovascular disease with a focus on socioeconomic differences as explanatory factors. Analyzing a contemporary population of natives and foreign-born individuals in Sweden, socioeconomic status is operationalized through a variety of measures. The importance of this study is found in the high cost of cardiovascular interThis doctoral thesis investigates the relationship between socioeconomic status and the onset of cardiovascular disease in a contemporary population of natives and foreign-born individuals in Sweden. The complexity of individual socioeconomic characteristics and the interrelationship with other cardiovascular risk factors is the focus of the studies in this thesis. As in most developed countries,