Conductive Electric Road Systems (ERS) appear as a promising solution for the electrification of transportation, particularly for heavy vehicles and long-distance trips but also for light vehicles. Significant research efforts are currently devoted to the development of conductive ERS systems, with up to four pilot test sites with different technologies in operation only in Sweden. With the help o

BACKGROUND: Patients with septic shock may undergo extensive physiological alterations that can alter antibiotic pharmacokinetics. OBJECTIVES: To describe the population pharmacokinetics of ciprofloxacin in septic shock and to define recommendations for effective ciprofloxacin dosing in these patients. METHODS: Adult patients with septic shock treated with ciprofloxacin were eligible for inclusion

Background and purpose — Children with cerebral palsy (CP) have an increased risk of hip dislocation. Outcome studies after surgery to prevent hip dislocation in children with CP are usually retrospective series from single tertiary referral centers. According to the national CP surveillance program in Sweden (CPUP), hip surgery should preferably be performed at an early age to prevent hip disloca

Objectives: Pain and disability are the main clinical manifestations of osteoarthritis, for which only symptomatic therapies are available. Hence, there is a need for therapies that can simultaneously alter disease progression and provide pain relief. KBP is a dual amylin- and calcitonin-receptor agonist with antiresorptive and chondroprotective properties. In this study we investigated the effect

Measurement of forces exerted by a human hand while performing common gestures is a highly valuable task for assessment of neurorehabilitation and neurological disorders, but also, for control of movement that could be directly transferred to assistive devices. Even though accurate and selective multi-joint measurement of hand forces is desirable in both clinical and research applications there is

Vi tittar upp nattetid och ser att vår Jord har en måne kretsande runt sig. Denna kallar vi Månen, och den har vi utforskat med hjälp av rymdsonder, olika landare och med hjälp av Apollo-astronauterna. Andra planeter har också månar kretsande runtom sig. Månar som ser helt annorlunda ut än vad vår egen Måne, vissa är små och ser ut som asteroider medans andra är så isiga att de skulle kunna förvanAs we look up at night we see that our Earth has one moon orbiting it, the one we call the Moon. We have explored our moon with orbiters, rovers and astronauts, mapping it and studying its history.Other planets also have moons in orbit around them and these may look quite different from the Earth's moon. Some are small and look like asteroids, others are so icy they would become comets if they plu

Aims: Research on the effect of unmet health-care needs on mortality at follow-up is scarce. This study investigated whether unmet health-care needs in 2008 were associated with a higher risk of mortality during a five-year follow-up period in a population in southern Sweden, and whether the association was stronger for particular subgroups of cause of death. Methods: The 2008 public-health survey

The key issue in urban drainage (UD) systems, looking from a control engineering perspective, is operation. Measurements, feedback, control and automation are tools to address the challenges. Measurement technology combined with analysis and parameter estimation are used to obtain relevant information for decision and control. The UD control problem is truly multivariable with many sensors and act

While a number of studies have found that an improvement in object shape recognition is associated with language growth in infants and toddlers, no published studies have investigated the longitudinal relation between early shape recognition, and language abilities in later childhood. An electrophysiological measure of semantic processing (the N400) was used to assess shape recognition and general

The progesterone metabolite, allopregnanolone (AlloP), is a GABAA receptor modulating steroid and is known to have orexigenic and pro-obesity effects. The neurobiological mechanisms underpinning these effects are most likely due to enhanced GABAergic signaling in the lateral arcuate nucleus (ARC) and medial paraventricular nucleus (PVN) of the hypothalamus. Inspired by the finding that GABAergic s

Background: Treating patients in cardiac arrest (CA) with mechanical chest compressions (MCC) during percutaneous coronary intervention (PCI) is now routine in many coronary catheterization laboratories (cath-lab) and more aggressive treatment modalities, including extracorporeal CPR are becoming more common. The cath-lab setting enables monitoring of vital physiological parameters and other clini

In this contribution a practical and rational decision-making approach is presented to be applied for common bridges typically managed by public authorities. The authors have developed a model with the intention to be applicable for practical cases for common bridges in the daily work of bride operators responsible for a large number of assets, yet still maintain the principles of more generic fra

The aim of this study was to develop a morphological model for long-term inlet evolution to be applied using a minimum amount of input data and requiring low computational costs. The model was implemented numerically and then validated for a real inlet application: Mundaú inlet (northeastern Brazil), a dynamic inlet with a marked freshwater seasonality and alongshore sand transport, reduced by ree

Background: Laccases are multicopper oxidases, which are assigned into auxiliary activity family 1 (AA1) in the CAZy database. These enzymes, catalyzing the oxidation of phenolic and nonphenolic substrates coupled to reduction of O2 to H2O, are increasingly attractive as eco-friendly oxidation biocatalysts. Basidiomycota laccases are well characterized due to their potential in de-lignification of

The potentially tridentate ligand bis[(1-methyl-2-benzimidazolyl)ethyl]amine (2BB) was employed to prepare copper complexes [(2BB)CuI]OTf and [(2BB)CuII(H2O)2](OTf)2 as bioinspired models of lytic polysaccharide copper-dependent monooxygenase (LPMO) enzymes. Solid-state characterization of [(2BB)CuI]OTf revealed a Cu(I) center with a T-shaped coordination environment and metric parameters in the r