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Identification of functional synonymous variants in familial breast cancer

The genetic causes of familial breast cancer are still unclear, where only less than 20% have evident germline mutations. Most studies focus on mutations that cause a direct impact in the protein, disregarding the synonymous variants, where the codon is changed but the amino acid encoded remains the same. Synonymous variants can affect mRNA stability and translation, by differences in codon usage

Product development and organisational strategies in the context of sustainability: A qualitative study examining sustainable product development and the consideration of micro-level sustainability strategies

This qualitative study investigates how organisations approach the development processes of sustainable products considering their micro-level sustainability efforts and ambitions and compare it to the model presented in the literature. The research follows a qualitative, social constructivist approach that enabled the researcher to work with pre-existing theories and the new empirical material. T

The effect of education on entrepreneurship: Examining the influence of new venture creation programs on entrepreneurial intention and behaviour

Although venture creation programs (VCPs) are becoming increasingly popular within entrepreneurship education, still little is known about how effective these programs actually are and if they foster more and better entrepreneurs compared to entrepreneurship master that do not oblige VCPs in their curriculum. Therefore, this thesis aims to analyse the differences in entrepreneurial intention and b

Making the Right Choice: the polarized US abortion debate and its transnational implications

The abortion debate in the United States has become increasingly polarized where the legality and morality of abortion is continuously discussed. This has given rise to an abortion movement and countermovement, commonly referred to as the pro- choice movement and pro-life movement. These movements are furthermore working transnationally to promote their agendas and contribute to social and politic

Fri bevisprövning utan fri tillgång till bevis - En granskning av användningen av biometriska register

The aim of this study is to examine how the use of, Swedish Police Authority wise, external biometric registers may be justified in regards of the opinion of professional actors versus the constitutional right to personal integrity. This is in order examine whether there is any indication that there is a discrepancy between the norms in the shape of opinions of professional actors regarding the us

centre for Vulnerable Youth

The present thesis explores the wide definition of homelessness and its complexity as a social phenomena. It is a very complex and multidirectional problem linked to individual, interpersonal, and socioeconomic factors. In order to prevent and minimize it and solve the problem in a sustainable, long run, the network of causes and triggering factors have to be found and understood. Often, the exist

The Application of Artistic Creative Type in Entrepreneurial Context: The motivation and creative behavior process

This thesis aims to explore whether an artistic creative type model can be applicable in an entrepreneurial setting. Meta Wagner’s model was selected as the artistic creative type model in this study. Conducting qualitative research through a case study approach on startup founders, who share a common background in entrepreneurial education, allows us to deepen our understanding of the founder

Voice Feature Extraction Using Siamese Neural Networks for Detecting Impersonators

Voice impersonation is a technique that has often been used by criminals whose goal is to avoid being identified while committing a crime. There are, however, other interesting cases where the police confronts a suspect with an incriminating recording, and the suspect would deny being the true speaker in that recording, and claim that it belonged to an expert impersonator. In both of these cases,

Are M-health Applications Accessible for Elders?

The rapid advancements in technology have brought benefits to many sectors, including the health sector. Popular technologies related to e-health and m-health have transformed traditional healthcare and are getting more popular among physicians and patients. Since these technologies, like any other, are constantly changing and improving, some groups of people who are not digitally literate enough

EU PUBLIC PROCUREMENT LAW - Can sustainability lawfully limit competition?

This thesis has as a purpose the investigation of sustainable requirements compliance with regards to competition in public procurement contracts. This paper looks into Directive 2014/24 and notably its primary law influence in order to understand the legal foundations underlying sustainability and competition. It showcases, firstly, that Article 18(1) wording and legal interpretation provides a l

An Investigation of Methods for Flow Measurements in a Gasketed Plate Heat Exchanger for Predictive Maintenance

For a company to stay relevant in the long term, it is essential to keep up with the latest technology and continuously consider new innovative solutions for improving products and services. The gasketed plate heat exchanger (GPHE) is a mechanical device, and this work attempts to investigate different possibilities for incorporating sensor devices and predictive maintenance systems to improve the

Hur resonerar svenska fastighetsbolag vid valet mellan intern och extern värdering av förvaltningsfastigheter?

Forskningsfrågor Hur resonerar svenska fastighetsbolag vid valet mellan intern och extern värdering av förvaltningsfastigheter? Hur resonerar fastighetsbolagen kring redovisningens kvalitativa egenskaper, relevans och tillförlitlighet? Syfte Uppsatsens syfte är att undersöka varför svenska fastighetsföretag väljer att anlita externa värderare. Studien syftar även till att undersöka hur fastighets

Experimental Study and Modelling of Heat Transfer in Milling of Titanium Alloys

The purpose of this project is studying heat transfer to indexable cutting tools during milling of a selection of titanium alloys, relevant to the industry. To achieve this goal, both experimental and theoretical models were contemplated to formulate the current thesis. The experimental set-up was designed and executed at Seco Tools AB, supporting the project as industrial collaborator. The therm

Performance and Wear Behaviour of Coated and Uncoated Cemented Carbide Tools during Milling of Titanium Alloys

Purpose – The purpose of this project is to study the performance of uncoated versus coated cemented carbide tools when performing milling operations in heat treated titanium alloys, with the goal of establishing a base line of knowledge and methodology linked to these difficult-to-machine materials relevant for the metal cutting industry. Design/methodology/approach – The work that is carried out

A preliminary study of evidence-based tool for wetland optimization - A case study using QSWAT+

Utförande av denna Masteruppsats är en del av projektet Ecodiver och i samarbete med vattenavdelningen på Lunds Tekniska Högskola. Syftet med studien är att granska den öppna källkods mjukvaran QSWAT+ som är ett plugin-program i QGIS. Detta för att i kommande tid kunna utveckla ett evidensbaserat verktyg för optimering av våtmarker. Undersökningsområdets omfattning är begränsad till Kävlingeåns avThis Master´s thesis is a part of the Ecodiver project, conducted by the Water department at LTH. The purpose of this study is to review the open-source software QSWAT+ as a plugin in QGIS, to be able to develop an evidence-based tool for optimization of wetlands. The scope of the study area is limited to the catchment area of Kävlinge river; however, no account is taken of the validation of data,

Examining the Evolution of Iran's Industrial Development under US-led Sanctions: A post-1979 perspective

The political and socioeconomic consequences of US-led sanctions on Iran have been extensively researched. Despite Iran's importance in natural resources such as oil, research on the domestic economic consequences of sanctions, particularly on Iranian industries, is largely disregarded. When the domestic perspective of the sanctioned country is factored out, socially recurring effects like sel