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SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density

Context: SHBG regulates free sex steroid levels, which in turn regulate skeletal homeostasis. Twin studies have demonstrated that genetic factors largely account for interindividual variation in SHBG levels. Glucuronidated androgen metabolites have been proposed as markers of androgenic activity. Objective: Our objective was to investigate whether polymorphisms in the SHBG gene promoter [(TAAAA)(n

Clinicians' management strategies for patients with dyspepsia: a qualitative approach

Background: Symptoms from the upper gastrointestinal tract are frequently encountered in clinical practice and may be of either organic or functional origin. For some of these conditions, according to the literature, certain management strategies can be recommended. For other conditions, the evidence is more ambiguous. The hypothesis that guided our study design was twofold: Management strategies

Arbetslöshet ekonomi och skam : Om att vara arbetslös i dagens Sverige

Popular Abstract in Swedish Avhandlingen syftar till att undersöka arbetslöshetens sociala konsekvenser och försöka ge en rimlig tolkning av variationer i arbetslöshetserfarenheter med hjälp av en teoretisk modell - ekonomi-skam modellen. Fokus ligger på att söka lyfta fram och visa på betydelsen av ekonomiska påfrestningar i kombination med skamupplevelser som en faktor för att förstå skillnader The purpose of this study has been to investigate the social consequences of unemployment and to give a possible interpretation of unemployment experiences through the application of the economy-shame model. It intends to put forward and show the significance of economic stress in combination with the feeling of shame as a factor important for the understanding of differences in unemploy-ment expe

Epitope spreading and autoimmune glomerulonephritis in rats induced by a T cell epitope of Goodpasture's antigen

An amino-terminal region of a, chain of type IV collagen noncollagenous domain [alpha(3)(IV)NC1] that induces experimental autoimmune glomerulortephritis (EAG) in rats has been identified. Only recombinant antigens that contain a nine-amino acid (AA) span of alpha(3)(IV)NC1, consistent with a T cell epitope, could induce EAG. It was hypothesized that synthetic peptides of this region should induce

Vesicle formation from temperature jumps in a nonionic surfactant system

When heating a dilute sample of the binary system of tetraethyleneglycol dodecyl ether (C12E4) and water from the micellar phase (L-1) into the two-phase region of a lamellar phase (L-alpha) and excess water (W) vesicles are formed. During heating, one passes a region of phase separation in the micellar phase (L-1' + L-1") where the initial micelles rapidly fuse into larger aggregates forming the

Time-course of liver fat accumulation in man after a single load of ethanol

Three healthy young male subjects were given a single load of ethanol (approximately 3 g/kg body weight) over 5 hours. Liver aspiration biopsies were performed at the start of the experiment and 6, 14, 24, and 48 hours after the start. Blood alcohol and serum transaminase activity levels were measured simultaneously. Triglycerides and phospholipids of the liver biopsy material were determined by a

Mild Microwave-Assisted Hydrolysis of Acetals Under Solvent-Free Conditions

Acetals are efficiently hydrolyzed with silica gel‐supported pyridinium tosylate moistened with water in solvent‐free conditions under microwave irradiation. The method is efficient and mild, with acid‐sensitive 3‐hydroxyacetals and 3‐methoxyacetals being hydrolyzed in minutes in good yields.

Vestibular evoked myogenic potentials in response to skull taps for patients with vestibular neuritis

In recent years it has been demonstrated that loud clicks generate short latency vestibular evoked myogenic potentials (VEMP). It has also been demonstrated that skull tap stimulation evokes similar VEMP. In the present study, the differences between the click-induced and the skull-tap induced VEMP were studied in 18 patients at onset of vestibular neuritis. Gentle skull taps were delivered manual

Determination of pore size distribution by suction porosimetry

Abstract in French La porosimétrie par succion repose sur la mesure de la dépression capillaire que suscite un liquide mouillant retenu dans un milieu poreux. C’est donc une méthode complémentaire à celle de la porosimétrie par pression (par ex. pénétration de mercure) où l’on opère avec des liquides mouillants. On expose la théorie et la pratique des méthodes par succion, entre autres les méthodeThe theory and practice of suction porosimetry methods (suction plate, pressure membrane and centrifuge) are reviewed together with related methods based on the rate of penetration of wetting liquids, and on static and dynamic fluid/fluid displacement measurements.

Anarki och magi

En läsning av Bruno K. Öijers författarskap som ett försök att bekämpa förtryck; detta sker via två vägar eller metoder: anarki och magi. Ytterst är poesin den kraft där dessa vägar sammanstrålar till fullo. Både textanalys och biografiska tolkningar ingår i mitt upplägg.

Distributed economies - A new engine for innovation

This article introduces' the concept of distributed economies (DE) as a fresh strategy to guide industrial development towards becoming more sustainable. The concept calls for a transformation in the industrial system towards DE departing from the socio-economically and environmentally unsustainable dynamics associated with large-scale, centralised production units that are favoured by neoclassica

The manifestation of symmetry between the emergence of consciousness and the development of competence

The article presents an experiment in which students, classified according to high and low analytical performance, were given a reading and text production test to determine their sensibility to the structure of an Icelandic saga. This material was used because of its extreme simplicity on the textual surface level, a property suited for studying structure as something beyond the surface. The hypo