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Safety of Automatic Emergency Braking in Platooning

A platoon comprises a string of consecutive highly automated vehicles traveling together. Platooning allows for increased road utilization and reduced fuel consumption due to short inter-vehicular distances. Safety in terms of guaranteeing no rear-end collisions is of utmost importance for platooning systems to be deployed in practice. We compare how safely emergency braking can be handled by emer

Search for Heavy Higgs Bosons Decaying into Two Tau Leptons with the ATLAS Detector Using pp Collisions at s =13 TeV

A search for heavy neutral Higgs bosons is performed using the LHC Run 2 data, corresponding to an integrated luminosity of 139 fb-1 of proton-proton collisions at s=13 TeV recorded with the ATLAS detector. The search for heavy resonances is performed over the mass range 0.2-2.5 TeV for the τ+τ-decay with at least one τ-lepton decaying into final states with hadrons. The data are in good agreement

Avoiding Routine Oxygen Therapy in Patients With Myocardial Infarction Saves Significant Expenditure for the Health Care System—Insights From the Randomized DETO2X-AMI Trial

Background: Myocardial infarction (MI) occurs frequently and requires considerable health care resources. It is important to ensure that the treatments which are provided are both clinically effective and economically justifiable. Based on recent new evidence, routine oxygen therapy is no longer recommended in MI patients without hypoxemia. By using data from a nationwide randomized clinical trial

Is staff consistency important to parents' satisfaction in a longitudinal study of children at risk for type 1 diabetes : the TEDDY study

BACKGROUND: Participants' study satisfaction is important for both compliance with study protocols and retention, but research on parent study satisfaction is rare. This study sought to identify factors associated with parent study satisfaction in The Environmental Determinants of Diabetes in the Young (TEDDY) study, a longitudinal, multinational (US, Finland, Germany, Sweden) study of children at

Functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries

OBJECTIVES: To describe functional and structural impairments of the pulmonary system in middle-aged people with cervical and upper thoracic spinal cord injuries (SCI), and compare findings to the general population. To determine if the neurological level of injury (NLI) is related to functional and structural impairments, and if age is related to structural impairments.DESIGN: Cross-sectional stu

ERC-ESICM guidelines on temperature control after cardiac arrest in adults

The aim of these guidelines is to provide evidence‑based guidance for temperature control in adults who are comatose after resuscitation from either in-hospital or out-of-hospital cardiac arrest, regardless of the underlying cardiac rhythm. These guidelines replace the recommendations on temperature management after cardiac arrest included in the 2021 post-resuscitation care guidelines co-issued b

Contact Allergy to Two Aluminum Salts in Consecutively Patch-Tested Dermatitis Patients

Background: Recently, aluminum chloride hexahydrate (ACH) 10.0% petrolatum (pet) was recommended for patch testing to detect aluminum contact allergy. Aluminum lactate (AL) may be as reliable a test substance as ACH. Objective: We aimed to investigate the frequencies of aluminum allergy when ACH and AL were used in patch testing consecutive patients. Methods: Petrolatum preparations of ACH 10.0% a

Plasma GFAP is an early marker of amyloid-β but not tau pathology in Alzheimer's disease

Although recent clinical trials targeting amyloid-β in Alzheimer's disease have shown promising results, there is increasing evidence suggesting that understanding alternative disease pathways that interact with amyloid-β metabolism and amyloid pathology might be important to halt the clinical deterioration. In particular, there is evidence supporting a critical role of astroglial activation and a

Human Rights as Law, Language, and Space-Making : Women’s Rights Movement in Post-Revolutionary Egypt

This dissertation analyses feminist activists’ use of human rights in post-revolutionary Egypt from 2011 to 2019. Drawing on interviews with feminist activists under three fieldwork trips, the dissertation investigates how: activists tried to implement gender equality in the country’s new constitutions, navigated the shrinking public space after 2013, sustained their activism against sexual violen

Ideal body image for the opposite sex and its association with body mass index

This research studied the preferences reported by women and men about their Ideal Body Image for the Opposite Sex (IBIOS), and its association with body mass index (BMI). It also analysed the preferences of each sex for a woman's ideal body image (W-IBI) and a man's ideal body image (M-IBI). A total of 450 participants aged 18-70 years with different weights were studied. Their IBIOS was assessed

Loewner-based Data-driven Iterative Structured Control Design

Stability enforcement remains a challenge in data-driven control paradigms, where no parametrised model of the system is available. In the Loewner Data-Driven Control framework (L-DDC) [1] for instance, the system's instabilities are estimated in order to enforce a closed-loop stability constraint on the controller reduction step. In order to avoid this preliminary estimation of instabilities, thi

Ribonucleotide reductase - Structural studies of a radical enzyme

Ribonucleotide reductase contains a stable organic free radical essential for its activity located on a tyrosine residue in the small subunit of the enzyme called R2. The substrate binding site is, however, found in the catalytic subunit called R1. A long-range protein-mediated radical transfer pathway appears to be responsible for the delivery of the radical from the tyrosine in R2 to the substra

20-Year Steady Increase in Survival of Adult Patients with Relapsed Philadelphia-Positive Acute Lymphoblastic Leukemia Post Allogeneic Hematopoietic Cell Transplantation

Purpose: Relapse after allogeneic hematopoietic cell transplantation (allo-HCT) remains the first cause of transplant failure in patients with Philadelphia-positive (Ph ) acute lymphoblastic leukemia (ALL). In other hematologic malignancies, therapeutic advances resulted in significant improvement over time in survival of patients relapsing after transplant. Experimental Design: We compared outcom

Virus Crystallography

Crystallography provides a means of visualizing intact virus particles as well as their isolated constituent proteins and enzymes (1, 2, 3) at near-atomic resolution, and is thus an extraordinarily powerful tool in the pursuit of a fuller understanding of the functioning of these simple biological systems. We have already expanded our knowledge of virus evolution, assembly, antigenic variation, an

Lipidomic risk scores are independent of polygenic risk scores and can predict incidence of diabetes and cardiovascular disease in a large population cohort

Type 2 diabetes (T2D) and cardiovascular disease (CVD) represent significant disease burdens for most societies and susceptibility to these diseases is strongly influenced by diet and lifestyle. Physiological changes associated with T2D or CVD, such has high blood pressure and cholesterol and glucose levels in the blood, are often apparent prior to disease incidence. Here we integrated genetics, l

The Meridian S02E07 : Ancient solar storms & observing reflections

In this last episode of the second season Nic and Rebecca get a visitor from the Department of Geology. One does not always use telescopes to study the stars. Chiara Paleari has been using ice cores to study our own star, the Sun, and has discovered evidence of an ancient solar storm. In this second season of the Meridian we are also bringing you some field reporting from the Nordic Optical Telesc

Vaccination Strategies and Immune Modulation of Atherosclerosis

Adaptive as well as innate immune responses contribute to the development of atherosclerosis. Studies performed in experimental animals have revealed that some of these immune responses are protective while others contribute to the progression of disease. These observations suggest that it may be possible to develop novel therapies for cardiovascular disease by selectively modulating such atheropr

Investigation of the p–Σ0 interaction via femtoscopy in pp collisions

This Letter presents the first direct investigation of the p–Σ0 interaction, using the femtoscopy technique in high-multiplicity pp collisions at s=13 TeV measured by the ALICE detector. The Σ0 is reconstructed via the decay channel to Λγ, and the subsequent decay of Λ to pπ−. The photon is detected via the conversion in material to e+e− pairs exploiting the capability of the ALICE detector to mea