This paper investigates the relationships between product architectures and global operations networks and their impact on operational performance, based on survey data from 82 Swedish manufacturers. We find that modular and integral product architectures are associated with different characteristics of the global operations network, and that global operations network designs are characterised by

Manufacturing firms with multiple product groups do not need to involve all factories in the production of all product groups. Some factories may specialize on a small set of products, while others participate in the manufacturing of a broader set of products. However, current theories on international manufacturing networks do not explain in detail how organizations design international manufactu

Heart failure (HF) is a morbid and heritable disorder for which the biological mechanisms are incompletely understood. We therefore examined genetic associations with HF in a large national biobank, and assessed whether refined phenotypic classification would facilitate genetic discovery. Methods: We defined all-cause HF among 488 010 participants from the UK Biobank and performed a genome-wide a

Surgical site infections (SSIs) in dermatologic surgery are rare, but when they do occur they can cause unnecessary suffering in patients, delayed healing, and result in poor scar cosmesis. The etiology and pathogenesis of SSIs in dermatologic surgery are not completely understood and most current preventative measures lack strong scientific evidence. Focusing on dermatologic surgery, this article

This chapter examines the Damages Directive and the issue of competence allocation between the Union and the Member States, by analysing the degree of comprehensiveness and detail of the Directive as well as future perspectives of full harmonisation on EU level. It is argued that the distinction between minimumand full harmonisation is not particularly helpful. Instead, we suggest an alternative u

During the 1980s the word ’postmodernism’ was inserted into the dicourse of Swedish literature in a curious way. Even though both writers and critics found the word bewildering – or deemed it a buzzword devoid of meaning – it sparked fierce debates. Despite this, and despite the fact that few wanted to be associated with the word, it has become common to describe the 1980s as the era of Swedish li

Background: Earlier research has investigated psychosocial and educational issues in populations of patients with cleft identifying several areas of concern. The objective of this study was to investigate current beliefs and knowledge about psychosocial and educational issues in parents and health care professionals (HCP) of children with cleft lip and/or palate (CL/P). Method: Parents were interv

Objective: To determine whether high DNA stainability (HDS), as assessed by the sperm chromatin structure assay (SCSA), predicts the risk of early miscarriage after in vitro fertilization with intracytoplasmic sperm injection (IVF-ICSI). Design: Retrospective cohort study of consecutive pregnancies after IVF and ICSI treatment. Setting: Reproductive medicine center. Patient(s): A total of 1,602 pr

Pulmonary hypertension is a common consequence of left heart disease, associated with poor prognosis. The pulmonary hypertension in left heart disease is initially caused by a passive congestion of the pulmonary circuit but may, if longstanding, result in endothelial dysfunction and excessive vasoconstriction. In some cases pulmonary vascular remodeling occur, further complicating the condition an

Objectives: To study associations between different anthropometric measures and incident gout, and to find the best predictive measure. Method: We used the baseline investigation from the Malmö Diet and Cancer study, excluding cases of prevalent gout (n = 28 081). Cox regression for each anthropometric measurement was calculated per standard deviation increment for men and women, with hazard ratio

Alzheimer’s disease (AD) is a progressive neurodegenerative disease in which the formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of intraneuronal tau and microglial activation are major pathological hallmarks. One of the key molecules involved in microglial activation is galectin-3 (gal3), and we demonstrate here for the first time a key role of gal3 in AD pa

Lignin is a heterogeneous aromatic biopolymer and a major constituent of lignocellulosic biomass, such as wood and agricultural residues. Despite the high amount of aromatic carbon present, the severe recalcitrance of the lignin macromolecule makes it difficult to convert into value-added products. In nature, lignin and lignin-derived aromatic compounds are catabolized by a consortia of microbes s

Educational collaboration activities are generally under-researched part of the interactive learning between universities and industry. The study based on 529 Master of Science (MSc) theses from a major Swedish engineering school, the faculty of engineering LTH at Lund University, shows that MSc theses are a frequently used collaboration mechanism between university and industry in engineering edu

Streptomyces spp. grow as branching hyphae, building the cell wall in restricted zones at hyphal tips. The organization of this mode of polar growth involves three coiled-coil proteins: DivIVA and Scy, which form apical protein complexes referred to as polarisomes; and the intermediate filament-like protein FilP, which influences cell shape and interacts with both Scy and DivIVA. Here, we use live

This paper presents a novel polynomial constraint for homographies compatible with the general planar motion model. In this setting, compatible homographies have five degrees of freedom-instead of the general case of eight degrees of freedom-and, as a consequence, a minimal solver requires 2.5 point correspondences. The existing minimal solver, however, is computationally expensive, and we propose

This paper is a reflection on market failure analysis in EU State aid law. Today, reliance upon market failure analysis is becoming more and more common in the practice of the Commission. Under Article 106(2) TFEU, it appears that market failure has increasingly been conceptualised as a part of the analysis of services of general economic interest (SGEI), which has been the subject to some researc