Introduction: The prognostic value of angina during exercise stress testing is controversial, possibly due to previous studies not differentiating typical from non-typical angina. We aimed to assess the prognostic value of typical angina alone, or in combination with ST depression, during exercise stress testing for predicting cardiovascular events. Methods: We conducted a prospective observationa

The goal of our research is the construction of efficient Jacobian-free preconditioners for high order Discontinuous Galerkin (DG) discretizations with implicit time integration. We are motivated by three-dimensional unsteady compressible flow applications, which often result in large stiff systems. Implicit time integrators overcome the impact upon restrictive CFL conditions on explicit ones but

A text may be seen as the result of input from the external world and human internal aspects on it. The paper shows how the same event — a submarine following a trawler — may give rise to different types (genres) of text, e.g., a report on the facts, an evaluation of the facts, a summary of the most important features against the background of previous events, or a mixture of some or all of these.

The health benefits of bean consumption are widely recognized and are largely attributed to the dietary fiber content. This study investigated and compared the effects of whole brown beans and an isolated bean dietary fiber fraction on the plasma lipid profile, atherosclerotic plaque amount, gut microbiota, and microbiota-dependent metabolites (cecal short-chain fatty acids (SCFAs) and plasma meth

Objective. To analyse how the main components of the disease phenotype (sicca symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by the age at diagnosis of primary Sjögren's syndrome (pSS). Methods. By January 2021, the participant centres had included 12,753 patients from 25 countries that fulfilled the 2002/2016 classification criteria for pSS. The age at diagn

Many jurisdictions have broadened the scope of criminalized sexual violence through the introduction of consent-based models. At the same time, measures have been taken in regards to the subjective elements for criminal liability in answer to a common defence in rape cases: namely, that the defendant lacked knowledge of the other person’s lack of consent. While some jurisdictions have introduced l

Aim: Identifying how climate change, habitat loss, and corridors interact to influence species survival or extinction is critical to understanding macro-scale biodiversity dynamics under changing environments. In North America, the ice-free corridor was the only major pathway for northward migration by megafaunal species during the last deglaciation. However, the timing and interplay among the lat

Sustainability of the enterprise is crucial to support long-term business survival and development. Unpredictable events such as Covid-19 highlights sustainability issues in enterprises. This empirical study aims to investigate sociotechnical sustainability in real world work practices. The focus is on employee involvement and problems in work practices concerning the economic, environmental, soci

The paracingulate sulcus is a tertiary sulcus formed during the third trimester. In healthy individuals paracingulate sulcation is more prevalent in the left hemisphere. The anterior cingulate and paracingulate gyri are focal points of neurodegeneration in behavioral variant frontotemporal dementia (bvFTD). This study aims to determine the prevalence and impact of paracingulate sulcation in bvFTD.

INTRODUCTION: Many patients with cognitive and neuropsychiatric symptoms face diagnostic delay and misdiagnosis. We investigated whether cerebrospinal fluid (CSF) neurofilament light (NfL) and total-tau (t-tau) could assist in the clinical scenario of differentiating neurodegenerative (ND) from psychiatric disorders (PSY), and rapidly progressive disorders.METHODS: Biomarkers were examined in pati