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The evolutionary stability of cross-sex, cross-trait genetic covariances

Although knowledge of the selective agents behind the evolution of sexual dimorphism has advanced considerably in recent years, we still lack a clear understanding of the evolutionary durability of cross-sex genetic covariances that often constrain its evolution. We tested the relative stability of cross-sex genetic covariances for a suite of homologous contact pheromones of the fruit fly Drosophi

Lessons from biomass planning at national and regional level in the EU

Abstract in UndeterminedAction plans are an important tool for meeting the EU renewable energy targets. Planning of biomass at national level has recently shifted from biomass action plans to renewable energy action plans; the latter still assigning special attention to biomass. A number of regions have also developed or are developing biomass plans. However, even though such plans are to assist t

Flunitrazepam intake in male offenders

The abuse of flunitrazepam (FZ) compounds is worldwide, and several studies have reflected on the consequences with regard to violence, aggression and criminal lifestyle of FZ users. Criminals take high doses of FZ or some other benzodiazepines to "calm down" before the planned crime. There is support from earlier studies that most likely, all benzodiazepines may increase aggression in vulnerable

Swedish Freight Demand: Short, Medium, and Long Term Elasticities

This paper explores empirical linkages between cycles and trends in freight transportation activity and real economic activity in Sweden. It decomposes freight demand into short-term, medium-term and long-term components and analyzes differences and similarities of the three time horizons. The finding is that freight demand is coupled with GDP over the long-term and that there are no signs of deco

Long-term drivers of forest composition in a boreonemoral region: the relative importance of climate and human impact

Aim To assess statistically the relative importance of climate and human impact on forest composition in the late Holocene. Location Estonia, boreonemoral Europe. Methods Data on forest composition (10 most abundant tree and shrub taxa) for the late Holocene (5100-50 calibrated years before 1950) were derived from 18 pollen records and then transformed into land-cover estimates using the REVEALS v

Is p-tert-butylphenol-formaldehyde resin (PTBP-FR) in TRUE Test (R) (Mekos test) sensitizing the tested patients?

Background. In a population study using TRUE Test (R), we noted late reactions to p-tert-butylphenol-formaldehyde resin (PTBP-FR) in 0.5% of subjects tested. Objectives. In order to explore possible test sensitization, differences in the contents of sensitizers within PTBP-FR in test preparations for TRUE Test (R) and Finn Chambers (R) were analysed. Subjects allergic to PTBP-FR and subjects with

Protein Expression Changes in Ovarian Cancer during the Transition from Benign to Malignant.

Epithelial ovarian carcinoma has in general a poor prognosis since the vast majority of tumors are genomically unstable and clinically highly aggressive. This results in rapid progression of malignancy potential while still asymptomatic and thus in late diagnosis. It is therefore of critical importance to develop methods to diagnose epithelial ovarian carcinoma at its earliest developmental stage,

The challenge of internal stakeholder support for co-creational branding strategy

This article focuses on co-creation as a strategy and the challenge of applying theories of co-creation in practice. Place branding and a co-creative strategy based on art is used as an example of a special type of public relations concerned with building connections between stakeholders and a specific place. This is investigated through an analysis of how key internal stakeholders in a municipali

Vertical oxide nanotubes connected by subsurface microchannels

We describe the fabrication of arrays of oxide nanotubes using a combination of bottom up and top down nanofabrication. The nanotubes are made from epitaxially grown semiconductor nanowires that are covered with an oxide layer using atomic layer deposition. The tips of the oxide-covered nanowires are removed by argon sputtering and the exposed semiconductor core is then selectively etched, leaving

A link between GIP and osteopontin in adipose tissue and insulin resistance.

Low grade inflammation in obesity is associated with accumulation of the macrophagederived cytokine osteopontin in adipose tissue and induction of local as well as systemic insulin resistance. Since GIP (glucose-dependent insulinotropic polypeptide) is a strong stimulator of adipogenesis and may play a role in the development of obesity, we explored whether GIP directly would stimulate osteopontin

Capacity of capsazepinoids to relax human small airways and inhibit TLR3-induced TSLP and IFNβ production in diseased bronchial epithelial cells.

Thymic stromal lymphopoietin (TSLP), an immunomodulating potentially disease-inducing cytokine, is overproduced in TLR3-stimulated bronchial epithelial cells from asthmatic donors whereas production of antiviral IFNβ is deficient. It is of therapeutic interest that capsazepine inhibits epithelial TSLP and relaxes human small airways with similar potencies. However, it is not known if other capsaze

Neurobiology: Jumping Spiders Getting On Board

A new technique has overcome decades of failure to allow, for the first time, electrophysiological access to the brains of jumping spiders, a group of animals renowned for generating highly complex, seemingly vertebrate-like behavior from their tiny arthropod brains.

Aerococcus: an increasingly acknowledged human pathogen.

Aerococci have often been misidentified as streptococci in microbiology laboratories, leading to an underestimation of these bacteria as causes of human infections. An increased awareness of aerococci and the introduction of matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS), has lead to an increased isolation of Aerococcus urinae and Aerococcus sanguinicol

Assessment of volume segmentation in radiotherapy of adolescents : a treatment planning study by the Swedish Workgroup for Paediatric Radiotherapy.

Background and purpose. The variability in target delineation for similar cases between centres treating paediatric and adolescent patients, and the apparent differences in interpretation of radiotherapy guidelines in the treatment protocols encouraged us to perform a dummy-run study as a part of our quality assurance work. The aim was to identify and quantify differences in the segmentation of ta

Ultra Low Power Error Correction Circuits- Technology Scaling and Sub-Vt operation

echniques are evaluated for implementing error- correction codes (ECC) in wireless applications with severe power constraints, such as bio-implantable devices and energy harvesting motes. Standard CMOS architectures are surveyed and compared against alternative implementations, including known sub-VT analog decoding techniques. Novel sub-VT digital designs are proposed and their power efficiency i

Joint scientific statement of the European Association for the Study of Obesity and the European Society of Hypertension: obesity and early vascular ageing.

Current cardiovascular risk scores do not include obesity or fat distribution as independent factors, and may underestimate risk in obese individuals. Assessment of early vascular ageing (EVA) biomarkers including arterial stiffness, central blood pressure, carotid intima-media thickness and flow-mediated vasodilation may help to refine risk assessment in obese individuals in whom traditional card

Novel assay to improve therapeutic drug monitoring of thiopurines in inflammatory bowel disease.

The thiopurines are widely used in the treatment of inflammatory bowel disease, but are limited by poor dose-effect relationship. The objective was to assess the ability of a novel assay, determining the mono-, di-, and triphosphates, of thioguanine as well as methylthioinosine as individual metabolites in erythrocytes, to predict clinical outcome compared to a routine assay, determining metabolit

Serine- and Arginine-rich Proteins 55 and 75 (SRp55 and SRp75) Induce Production of HIV-1 vpr mRNA by Inhibiting the 5 '-Splice Site of Exon 3

HIV-1 non-coding exon 3 can either be spliced to exons 4, 4a, 4b, 4c, and 5 to generate tat, rev, and nef mRNAs or remain unspliced to produce the 13a7 vpr mRNA. Here we show that serine-and arginine-rich proteins 55 and 75 (SRp55 and SRp75) inhibit splicing from the 5'-splice site of exon 3 thereby causing an accumulation of the partially unspliced 13a7 vpr mRNA. In contrast, serine- and arginine

Service User Integration Into Social Work Education: Lessons Learned From Nordic Participatory Action Projects

Service users have lacked substantial influence, access, and participation in social work education in Norway and Sweden. This article presents comparative analyses of two participatory projects that have developed and implemented practices that integrate service users into academic social work education and empower service users. The Norwegian HUSK project and the Social Mobilization, Community W

A self-determination theory approach to predicting school achievement over time: The unique role of intrinsic motivation

Although many studies have examined the relation of academic motivation to school achievement using the Self-Determination Theory perspective, the results have been inconsistent. The present investigation represents the first systematic attempt to use a meta-analysis and controlled, longitudinal studies to examine the relations of specific types of motivation to overall academic achievement. The m