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ACN-Sim : An Open-Source Simulator for Data-Driven Electric Vehicle Charging Research

ACN-Sim is a data-driven, open-source simulation environment designed to accelerate research in the field of smart electric vehicle (EV) charging. It fills the need in this community for a widely available, realistic simulation environment in which researchers can evaluate algorithms and test assumptions. ACN-Sim provides a modular, extensible architecture, which models the complexity of real char

High-dimensional channel estimation for simultaneous localization and communications

Simultaneous localization and communication (SLAC) is a desirable feature of 5G and beyond 5G wireless networks. To be able to implement SLAC, efficient high dimensional channel estimation methods are critical. This work presents a low-complexity multidimensional channel parameter estimation via rotational invariance techniques (MD-ESPRIT). We use both the spatial smoothing and forward-backward av

A modified Jarzynski free-energy estimator to eliminate non-conservative forces and its application in nanoparticle-membrane interactions

Computational methods to understand interactions in bio-complex systems are however limited to time-scales typically much shorter than in Nature. For example, on the nanoscale level, interactions between nanoparticles (NPs)/molecules/peptides and membranes are central in complex biomolecular processes such as membrane-coated NPs or cellular uptake. This can be remedied by the application of e.g. J

Anion-cation contrast of small molecule solvation in salt solutions

The contributions from anions and cations from salt are inseparable in their perturbation of molecular systems by experimental and computational methods, rendering it difficult to dissect the effects exerted by the anions and cations individually. Here we investigate the solvation of a small molecule, caffeine, and its perturbation by monovalent salts from various parts of the Hofmeister series. U

Can reflective diary-writing increase sufficiency-oriented consumption? A longitudinal intervention addressing the role of basic psychological needs, subjective well-being, and time affluence

Sufficiency is a sustainability strategy aiming for (1) a decrease in absolute resource consumption on individual and societal levels, and (2) for socio-ecological justice and the fair distribution of costs and benefits of resource use to meet every human’s basic needs. This study examined a longitudinal intervention to foster individual sufficiency orientation (i.e., a multidimensional con-struct

Climate change through the lens of self-determination theory : How considering basic psychological needs may bring environmental psychology forward

In this paper, I argue for how environmental psychology as a discipline could benefit both conceptually and practically from considering basic psychological needs as specified within Self-Determination Theory (Ryan & Deci, 2017). I begin with a definition of basic psychological needs as “innate psychological nutriments that are essential for ongoing psychological growth, integrity, and well-be

Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol

OBJECTIVE LDL cholesterol (LDLc)-lowering drugs modestly increase body weight and type 2 diabetes risk, but the extent to which the diabetogenic effect of lowering LDLc is mediated through increased BMI is unknown. RESEARCH DESIGN AND METHODS We conducted summary-level univariable and multivariable Mendelian randomization (MR) analyses in 921,908 participants to investigate the effect of lowering

Column separation of monocytes by adherence to gelatin beads

This investigation was performed to study whether the efficient binding of collagen to monocytes in the presence of fibronectin and heparin may be used for separation of monocytes from human peripheral blood. It was shown that monocytes adhere selectively to gelatin bead columns in the presence of fresh plasma and heparin. Mononuclear blood cells are rapidly depleted of monocytes by passage throug

Temporal Patterns of Glucagon and Its Relationships with Glucose and Insulin following Ingestion of Different Classes of Macronutrients

Background: glucagon secretion and inhibition should be mainly determined by glucose and insulin levels, but the relative relevance of each factor is not clarified, especially following ingestion of different macronutrients. We aimed to investigate the associations between plasma glucagon, glucose, and insulin after ingestion of single macronutrients or mixed-meal. Methods: thirty-six participants

Connecting Cohorts to Diminish Alzheimer's Disease (CONCORD-AD) : A Report of an International Research Collaboration Network

Longitudinal observational cohort studies are being conducted worldwide to understand cognition, biomarkers, and the health of the aging population better. Cross-cohort comparisons and networks of registries in Alzheimer's disease (AD) foster scientific exchange, generate insights, and contribute to the evolving clinical science in AD. A scientific working group was convened with invited investiga

Immune functions in melanoma patients during treatment with interferon [HuIFN-alpha (Le)] alone or in combination with cimetidine

While leukocyte interferon was found therapeutically ineffective in a series of 20 patients with metastatic malignant melanoma, subsequent combination treatment with interferon and cimetidine induced 5 complete and 1 partial tumour remissions. Prior to interferon therapy initiation, regressor patients demonstrated a significantly greater ability to mediate antibody-dependent cellular cytotoxicity