In this paper, we investigate the possibility of using accurate prediction models for the prediction of protoporphyrin bleaching dynamics to achieve photobleaching-insensitive methods to improve the evaluation of data in an existing clinical fluorescence-guided resection technique. To simulate the scenario, measurements were carried out in vivo on skin of healthy volunteers using a compact fiber-b

Popular Abstract in Undetermined 1971 förklarade president Richard Nixon, som så många amerikanska presidenter före honom, krig. Nixons fiende var dock något oortodox; Nixon förklarade krig mot cancer. I och med att senaten godkände ”National Cancer Act”, av pressen snabbt döpt till ”War on cancer”, hoppades Nixon att kunna utradera cancer med hjälp av kraftigt ökade anslag till cancerforskning koDespite recent advances in cancer treatment, truly innovative approaches are required to move beyond the modest benefits achieved to date. HAMLET is a human protein-lipid complex originally discovered in breast milk able to kill a wide range of tumour cells while leaving healthy, differentiated cells unaffected. The aim of this thesis was to identify mechanisms dictating HAMLET sensitivity and to

The near-field radiation pattern of a long thin slit (with a width much smaller than the excitation wavelength) in a uniform aluminum surface was measured and modeled by numerical computation. In particular, the interplay between the incident light polarization and the slit width is found to play an essential role in the near-field profile on the back side of the nanoslits. Two-dimensional finite-

InP nanowires are fabricated by organo-metallic vapour phase epitaxy and studied via photoluminescence measurements performed on single nanowires, finding evidence of state filling with increasing excitation power density. To increase flexibility in fabrication technology we developed a wet chemical procedure to grow a CdS shell on these wires. In these InP-CdS wires the luminescence efficiency wa

The article presents two Matlab-based tools for analysis andsimulation of real-time control systems: Jitterbug andTrueTime.Jitterbug allows the user to compute aquadratic performance criterion for a linear control system undervarious timing conditions. The control system is described using anumber of continuous- and discrete-time linear systems. Astochastic timing model with random delays is used

The prime objective of this study is to investigate if radioluminescence (RL) from carbon-doped aluminum oxide (Al2O3:C) crystals potentially can be used for absorbed dose-rate measurements during proton radiotherapy. The RL from two separate (2 mg) Al2O3:C crystals attached to optical-fiber cables were recorded during irradiations in water in a 175 MeV clinical proton beam. The RL response for lo

An account is given of the general morphology, reproductive biology, ecology and historical exploration of the green alga order Oedogoniales. About 150 species belonging to the genera Oedogonium and Bulbochaete have been recorded from Sweden during the period 1864–1964. Notably, more than 80 taxa were described as new for science based on material from Swedish sites by the Scandinavian algologists

Many extensions of the Standard Model predict the existence of charged heavy long-lived particles, such as R-hadrons or charginos. These particles, if produced at the Large Hadron Collider, should bemoving non-relativistically and are therefore identifiable through the measurement of an anomalously large specific energy loss in the ATLAS pixel detector. Measuring heavy long-lived particles through

We provide certain unusual generalizations of Clausen's and Orr's theorems for solutions of fourth-order and fifth-order generalized hypergeometric equations. As an application, we present several examples of algebraic transformations of Calabi-Yau differential equations.

Ischemic heart disease is the leading cause of death in high-income parts of the world and is caused mainly by atherosclerosis in the coronary arteries. The rupture of an atherosclerotic plaque with subsequent platelet activation and clot formation can lead to myocardial infarction (MI). Atherosclerosis is a complex process, which involves the accumulation and oxidation of low-density lipoprotein

Background: The data concerning the effects and safety of androgen in human breast tissue are conflicting. Objective: Our aim was to analyze the effects of androgens on normal human breast tissue (HBT). Approach: We cultured explants of HBT (obtained from reduction mammoplasty operations of postmenopausal women) with or without testosterone (T) and 5α-dihydrotestosterone (DHT) or in combination

Investigations on exposure to electromagnetic have generated conflicting results both in epidemiological and laboratory studies, leaving their possible health consequences largely inconclusive. One of the well-reported reasons for the discrepancies is that there is no generally accepted theory to describe the interactions between the very weak electromagnetic fields and the living cells. This work

Objectives: To describe energy intake and its macronutrient and food sources among 27 regions in 10 countries participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods: Between 1995 and 2000, 36 034 subjects aged 35-74 years were administered a standardized 24-h dietary recall. Intakes of macronutrients (g/day) and energy (kcal/day) were estimated usin