Search results

Filter

Filetype

Your search for "*" yielded 528858 hits

Photoacoustic imaging for the monitoring of local changes in oxygen saturation following an adrenaline injection in human forearm skin

Clinical monitoring of blood oxygen saturation (sO2) is traditionally performed using optical techniques, such as pulse oximetry and diffuse reflectance spectroscopy (DRS), which lack spatial resolution. Photoacoustic imaging (PAI) is a rapidly developing biomedical imaging technique that is superior to previous techniques in that it combines optical excitation and acoustic detection, providing a

Postmortem Studies of Fetal Grafts in Parkinson’s Disease : What Lessons Have We Learned?

Neural transplantation is a potential therapeutic method for Parkinson’s disease (PD). Fetal dopaminergic (DA) neurons have been important transplantation cell sources in the history of replacement therapy for PD. Several decades of preclinical animal experiments and clinical trials using fetal DA neuron transplantation in PD therapy have shown not only promising results but also problems. In orde

Maximum Rate and Minimal Duration of Repeated Syllables

Among the interesting questions related to tongue-twisters is the question how fast syllables of different types can be repeated. A simple pilot experiment with strings of open syllables such as [tatata...], [stastasta...], [strastrastra ...] was carried out. Differences in the results are interpreted as being due to individual differences in motor skills and to differences in the phonetic materia

Phenolic wastewaters depuration by electrochemical oxidation process using Ti/IrO2 anodes

The electrochemical oxidation (EO) of phenolic wastewaters mimicking olive oil mill effluents was carried out in a batch stirring reactor using Ti/IrO2 anodes, varying the nature (NaCl and Na2SO4) and electrolyte concentration (1.8-20 g L-1), current density (57-119 mA cm(-2)) and initial pH (3.4-9). Phenolic content (TPh) and chemical oxygen demand (COD) removals were monitored as a function of a

Early mitochondrial metabolism and dynamics changes as predictors of neurodegeneration and neuronal cell death

Background: Neuronal calcium and ATP homeostasis is regulated through alterations in mitochondria fusion/fission events and anterograde and retrograde transport in neurons. Mitochondrial dynamics form an interactome that ultimately controls mitochondrial quality, quantity and metabolism. Our objective is to show that alterations in this interactome lead to point-of-no-return situations characteriz

Antithetic Sampling for Monte Carlo Differentiable Rendering

Stochastic sampling of light transport paths is key to Monte Carlo forward rendering, and previous studies have led to mature techniques capable of drawing high-contribution light paths in complex scenes. These sampling techniques have also been applied to differentiable rendering.In this paper, we demonstrate that path sampling techniques developed for forward rendering can become inefficient for

Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene

Cooper-Knock et al. identify amyotrophic lateral sclerosis (ALS) risk variants within non-coding regulatory DNA linked to a known ALS gene, TBK1, but also CAV1 and CAV2. Disease-associated variants reduce CAV1/CAV2 expression and disrupt membrane lipid rafts with consequences for neurotrophic signaling. CAV1 coding sequence also contains ALS-associated mutations. © 2020 The Author(s) Amyotrophic l

PLM used as a backbone for concurrent engineering in supply chain

Supply chain management and early involvement of suppliers into product development process is one of the key elements of concurrent engineering. Internet based Product Lifecycle Management (PLM) system can improve communication between customers and suppliers. In the case study is presented a communication model and configuration of the PLM system that supports a second tier system supplier in au

Energy communities in different national settings – barriers, enablers and best practices

The NEWCOMERS project aims to explore how new clean energy communities (ECs) develop, under which polycentric settings ECs evolve and under what conditions such initiatives are suppressed. At a national level, the project will assess socio-economic, technical, institutional characteristics and actors supporting the emergence of new clean energy communities. In Deliverable 3.1. and 3.2. the nationa

What is commensality? A critical discussion of an expanding research field

Commensality (the act of eating together) is studied in a range of disciplines and often considered important for social communion, order, health and well-being, while simultaneously being understood as in decline (especially the family meal). However, such claims are also contested in various ways. In this paper, we discuss the expanding field of commensality research and critically reflect on th

Postural orthostatic tachycardia syndrome (POTS) : State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1

Postural orthostatic tachycardia syndrome (POTS) is a chronic and often disabling disorder characterized by orthostatic intolerance with excessive heart rate increase without hypotension during upright posture. Patients often experience a constellation of other typical symptoms including fatigue, exercise intolerance and gastrointestinal distress. A typical patient with POTS is a female of child-b

Application of ERA-Interim, empirical models, and an artificial intelligence-based model for estimating daily solar radiation

Solar radiation plays a pivotal role in the energy balance at the Earth's surface, evaporation, snow melting, water requirements of plants, and hydrological control of catchments. In this work, performance of ERA-Interim (a reanalysis dataset) was examined to estimate solar radiation at Ahvaz, BandarAbbas, and Kermanshah weather stations representing the even spatial distribution over Iran using e

Kinetic and Thermodynamic Modeling of Nanowire Growth

This thesis aims to expand on the fundamental knowledge of crystal growth, selectively focusing on the area of particle-seeded nanowire growth in the III-V materials system. The growth process is complex. It typically occurs via the vapor-liquid-solid method, wherein growth material is supplied in the vapor phase, but the solidification process occurs dynamically, layer by layer, via an intermedia