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Adjuvant radiotherapy after radical prostatectomy

Background: Within 5 years following radical prostatectomy, between 15 and 60% of patients with pT3 prostate carcinomas show an increasing prostate-specific antigen (PSA) as a sign of local and/or systemic tumour progression. Adjuvant radiotherapy (RT) for positive margins (RI) aims to reduce residual tumour cells in the prostatic bed, thus possibly reducing the biochemical progression rate. Apart

Effect of environmental enrichment on stress related systems in rats

The aim of this study was to test whether environmental enrichment alters the status and responsiveness of pituitary-adrenocortical and sympathetic-adrenomedullary hormones in rats. Previous studies have shown that rats kept in an enriched environment differ from those kept in standard cages in dendritic branching, synaptogenesis, memory function, emotionality and behaviour. In male Wistar rats ke

Actions of sex steroids and corticosteroids on rabbit choroid plexus as shown by changes in transport capacity and rate of cerebrospinal fluid formation

The effect of betamethasone on choroid plexus transport and CSF formation in rabbits was studied. Following 5 days of daily treatment with betamethasone the CSF production rate was reduced by 43% as measured by ventriculo-cisternal perfusion with radioactive inulin. Accordingly, the Na(+)-K(+)-ATPase activity and the transport capacity in the choroid plexus, measured in terms of choline (10(-5) M)

Öresundsregion - bli till! : De geografiska visionernas diskursiva rytm

Popular Abstract in Swedish Avhandlingens syfte är att kartlägga och analysera hur geografiska visioner utgjort diskursiva redskap i en specifik framtidsorienterad process, institutionaliseringen av Öresundsregionen.This thesis is about how geographical visions worked as discursive tools in the institutionalisation of the Öresund Region. The geographical vision is defined as a cognitive set of imagined and material pictures of the future structured as a spatial whole. The geographical vision is, in addition to this, a spaceconfiguration-, power-, and disciplinary - instrument, and, the product of a discursiv

Post-termination complex disassembly by ribosome recycling factor, a functional tRNA mimic

Ribosome recycling factor (RRF) together with elongation factor G (EF-G) disassembles the post- termination ribosomal complex. Inhibitors of translocation, thiostrepton, viomycin and aminoglycosides, inhibited the release of tRNA and mRNA from the post-termination complex. In contrast, fusidic acid and a GTP analog that fix EF-G to the ribosome, allowing one round of tRNA translocation, inhibited

Neuronal plasticity and dendritic spines: effect of environmental enrichment on intact and postischemic rat brain.

The authors compared the influence of environmental enrichment on intact and lesioned brain, and tested the hypothesis that postischemic exposure to an enriched environment can alter dendritic spine density in pyramidal neurons contralateral to a cortical infarct. The middle cerebral artery was occluded distal to the striatal branches in spontaneously hypertensive rats postoperatively housed eithe

The impact of stent design on proximal stent-graft fixation in the abdominal aorta: an experimental study

OBJECTIVE: to study the proximal fixation of different aortic stent grafts in comparison to a hand-sewn anastomosis. DESIGN: experimental study. MATERIAL: the infrarenal aorta of 16 human cadavers were exposed, left in situ and transected 3 cm above the aortic bifurcation to mimic an infrarenal aortic neck. Stent grafts were deployed through a sheath 5 cm into the aorta. Ancure, Talent, Vanguard,

Impact of natural and artificial UVB radiation on motility and growth rate of marine dinoflagellates

The growth rates and motility of dinoflagellates were studied in the field in the presence or absence of UVB radiation, as well as in the laboratory under artificial radiation conditions. Photosynthetically active radiation (PAR, 400–700 nm) and UVB radiation showed large variations due to cloud cover and seasonal changes in natural daylight. In Swedish coastal water, UVB radiation was attenuated

Energy transfer within Zn-porphyrin dendrimers: Study of the singlet-singlet annihilation kinetics

In this article, we explore energy transfer processes within a series of Zn-porphyrin-appended dendrimers by means of excitation intensity dependent transient absorption measurements. We report singlet-singlet annihilation on two distinct time scales of 18 +/- 5 ps and 130 +/- 10 ps in the dimer and the dendrimers. The two distinct processes reflect the presence of two structural conformer distrib