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Content Analysis of Four Fear of Falling Rating Scales by Linking to the International Classification of Functioning, Disability and Health.

OBJECTIVE: To gain a deeper understanding of the content of 4 fear of falling (FOF) rating scales by linking them to the International Classification of Functioning, Disability and Health (ICF). DESIGN: Linking study according to the ICF linking rules. SETTING: Not applicable. PATIENTS: Not applicable. METHODS: The rating scales were the Falls Efficacy Scale-International (FES-I), the Swedish vers

Persistent organic pollutants and male reproductive health

Environmental contaminants such as persistent organic pollutants (POPs) are man-made bioaccumulative compounds with long half-lives that are found throughout the world as a result of heavy use in a variety of consumer products during the twentieth century. Wildlife and animal studies have long suggested adverse effects of exposure to these compounds on human reproductive health, which, according t

Tumor Targeting Using Affibody Molecules: Interplay of Affinity, Target Expression Level, and Binding Site Composition.

Radionuclide imaging of cancer-associated molecular alterations may contribute to patient stratification for targeting therapy. Scaffold high-affinity proteins, such as Affibody molecules, are a new, promising class of probes for in vivo imaging. Methods. The effects of human epidermal growth factor receptor 2 (HER2) affinity and binding site composition of HER2-binding Affibody molecules, and of

T wave alternans in experimental myocardial infarction: Time course and predictive value for the assessment of myocardial damage.

BACKGROUND: T-wave alternans (TWA) is associated with prognosis after myocardial infarction (MI), however its link to the extent of ischemic injury has not been clarified. We analyzed the course of TWA and its relation to myocardial damage in experimental myocardial infarction. METHODS: In 21 pigs, infarction was induced by 40-minute long balloon inflation in LAD under continuous 12-lead ECG monit

Improved microbial electrocatalysis with osmium polymer modified electrodes.

Using the well-known exoelectrogen Shewanella oneidensis MR-1, an osmium redox polymer modified anode exhibited ca. 4-fold increase in current generation. Additionally, a significant decrease in the start-up time for electrocatalysis was observed. The findings suggest that the inherent extracellular electron transfer capabilities of electrogens coupled with such polymers could enhance electrocatal

Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice

The 8p11 myeloproliferative syndrome (EMS), also referred to as stem cell leukemia/lymphoma, is a chronic myeloproliferative disorder that rapidly progresses into acute leukemia. Molecularly, EMS is characterized by fusion of various partner genes to the FGFR1 gene, resulting in constitutive activation of the tyrosine kinases in FGFR1. To date, no previous study has addressed the functional conseq

Neutron powder diffraction - new opportunities in hydrogen location in molecular and materials structure

The potential of neutron powder diffraction in the location of hydrogen atoms in molecular materials and inorganic-molecular complexes is reviewed. Advances in instrumentation and data collection techniques that have made this field accessible are reviewed, along with a wide range of applications carried out by our collaboration investigating functional materials, hydrogen-containing minerals and

Characterization and validation of the frequency-modulated continuous-wave technique for assessment of photon migration in solid scattering media

The frequency-modulated continuous-wave (FMCW) technique, based on the beat signal of a Mach– Zehnder interferometer employing a frequency-ramped light source, is studied for solid scattering media applications. The method is used to evaluate the mean time-of-flight (MTOF) of light traveling in scattering media, specifically polystyrene foams. We assume that each the time-of-flight (TOF) time corr

The audit juggernaut : Comment on Audit Culture articles

Anthropologists studying audit culture focus on the success of rankings, ratings and indicators in constituting or reproducing discourses, a kind of audit juggernaut of power. But in fact, alot of these rankings have no impact at all. The short commentary, part of a group of papers on audit culture, rankings and indicators, compares the Transparency International Corruption Perception Index with t

Nomological Resemblance

Laws of nature concern the natural properties of things. Newton’s law of gravity states that the gravitational force between objects is proportional to the product of their masses and inversely proportional to the square of their distance; Coulomb’s law states a similar functional dependency between charged particles. Each of these properties confers a power to act as specified by the function of

Client involvement in home care practice: a relational sociological perspective.

GLASDAM S, HENRIKSEN N, KJaeR L and PRAESTEGAARD J. Nursing Inquiry 2012 [Epub ahead of print] Client involvement in home care practice: a relational sociological perspective 'Client involvement' has been a mantra within health policies, education curricula and healthcare institutions over many years, yet very little is known about how 'client involvement' is practised in home-care services. The a

Timing and climate forcing of volcanic eruptions for the past 2,500 years

Volcanic eruptions contribute to climate variability, but quantifying these contributions has been limited by inconsistencies in the timing of atmospheric volcanic aerosol loading determined from ice cores and subsequent cooling from climate proxies such as tree rings. Here we resolve these inconsistencies and show that large eruptions in the tropics and high latitudes were primary drivers of inte

APC-PCI complex levels for screening of AAA in patients with peripheral atherosclerosis.

To evaluate the use of activated protein C-protein C inhibitor (APC-PCI) complex levels for detection of abdominal aortic aneurysm (AAA) in patients with peripheral atherosclerotic disease (PAD). APC-PCI levels and aortic diameter evaluated in 511 PAD patients without previously known AAA followed-up concerning survival for 4.8(0.5) years. AAA was found in 13 % of patients. Aortic diameter correla

Characterization and assembly of a GFP-tagged cylindriform silk into hexameric complexes.

Spider silk has been studied extensively for its attractive mechanical properties and potential applications in medicine and industry. The production of spider silk, however, has been lagging behind for lack of suitable systems. Our approach focuses on solving the production of spider silk by designing, expressing, purifying and characterizing the silk from cylindriform glands. We show that the cy

The enzyme thermistor-A realistic biosensor concept. A critical review.

This review describes principles and features of thermal biosensors and microbiosensors in flow injection analysis. Examples are given that illustrate the great versatility and excellent operational stability offered by thermal biosensors. The examples are mostly from work with the original type of enzyme thermistor operating with an enzyme column, but there will also be work described involving m

Testing for structural breaks in the presence of data perturbations: impacts and wavelet-based improvements

This paper investigates how classical measurement error and additive outliers (AO) influence tests for structural change based on F-statistics. We derive theoretically the impact of general additive disturbances in the regressors on the asymptotic distribution of these tests for structural change. The small sample properties in the case of classical measurement error and AO are investigated via Mo

Clinical Outcome of Patients Transplanted with Marginal Donor Lungs via Ex Vivo Lung Perfusion Compared to Standard Lung Transplantation.

Lung transplantation is limited by a scarcity of suitable donors resulting in high waiting list mortality. Ex vivo lung perfusion (EVLP) allows the evaluation and reconditioning of marginal donor lungs for use in transplantation. This study aimed to compare clinical outcome of patients transplanted with marginal organs by means of EVLP with a standard lung transplant cohort through a multicenter o