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Production of bio-based adipic acid using a combination of engineered Pseudomonas putida strains

Adipic acid is an industrially important dicarboxylic acid and an essential precursor in the synthesis of Nylon-6,6. Due to the environmental impact associated with the current synthetic methods for Nylon-6,6 production, greener alternatives based on renewable and bio-based feedstocks are needed. In the present study, the potential of two Pseudomonas putida strains engineered for muconic acid

Toward low-carbon ways of life : The cultural politics of contesting aeromobility

För snart ett decennium sedan startade en intensiv debatt om flygets klimatpåverkani svenska medier. I dess kölvatten har en social rörelse för minskat flygresande tagitform – flygfrittrörelsen. Den består av individer och organisationer som tillsammansengagerar sig för minskat flygresande, dels genom att delta i kampanjer och annatpåverkansarbete, och dels genom att själva avstå flygresande.Min aThe need for demand-side climate solutions is increasingly recognized in science and society. Such solutions imply that demand for goods and services is targeted either via changes in the use of infrastructure and technology or via cultural changes in consumption and lifestyle among the global affluent. In this thesis, I explore how to enable cultural change around affluent overconsumption through

Nutritional Composition of Six Amaranth (Amaranthus caudatus) Andean Varieties

Amaranthus caudatus is a nutrient-rich Andean pseudocereal with wide genetic variability. Six productive varieties (Oscar Blanco, Pucara, Tomina, Cotahuasi, Barbechos, and Guindo Criollo) were compared by proximate, mineral, and fatty acid composition. The proximal content showed certain singularities in the varieties. Barbechos and Guindo Criollo stood out for their fat content (9.50% and 9.01%,

Talking The Talk but Not Walking the Walk : Is the Use of Sustainability Keywords in IS/IT Job Ads “Greenwashing”?

This paper explores the intersection of corporate sustainability and recruitment perspectives in Swedish companies, examining the use of one hundred and seven sustainability keywords in more than 230 000 IS/IT job ads collected from the Swedish Public Employment Service. The study emphasizes the pressing need for a new breed of computing professionals to address environmental challenges and climat

AACC Approved Methods Technical Committee Report: Crack Resistance and Translucency Determination of Paddy Rice Kernels Using the PaddyCheck Instrument

Physical properties such as break resistance, chalkiness, and size dimensions are very important for grading rice quality. Today, most of the methods used for determining these properties are performed manually, making them both time-consuming and, to some extent, subjective, which, in turn, can affect the determination of rice quality and, thereby, the price. A collaborative study was conducted b

Progression to type 1 diabetes in the DPT-1 and TN07 clinical trials is critically associated with specific residues in HLA-DQA1-B1 heterodimers

AIMS/HYPOTHESIS: The aim of this work was to explore molecular amino acids (AAs) and related structures of HLA-DQA1-DQB1 that underlie its contribution to the progression from stages 1 or 2 to stage 3 type 1 diabetes.METHODS: Using high-resolution DQA1 and DQB1 genotypes from 1216 participants in the Diabetes Prevention Trial-Type 1 and the Diabetes Prevention Trial, we applied hierarchically orga

Fabrication and Electrocatalytic Evolution of Alkali-Free CoNb2O6 Thin Films for Water Oxidation via Polyoxoniobates

Fabrication of CoNb2O6 thin films was possible through spin-coating an alkali-free, aqueous solution of a polyoxoniobate ([Nb10O28]6-, Nb10) and a cobalt nitrate (Co(NO3)2), followed by annealing. The results showed that depending on the calcination conditions, minor phases of unreacted Co3O4 and β-Nb2O5 may form alongside the columbite CoNb2O6 phase. However, optimizing the calcination conditions

Spatial multiomics reveal intratumoral immune heterogeneity with distinct cytokine networks in lung cancer brain metastases

The tumor microenvironment of brain metastases has become a focus in the development of immunotherapeutic drugs. However, countless brain metastasis patients have not experienced clinical benefit. Thus, understanding the immune cell composition within brain metastases, and how the immune cells interact with each other and other microenvironmental cell types, may be critical for optimizing immunoth

The role of dendritic cells in tertiary lymphoid structures: implications in cancer and autoimmune diseases : Mariana Reste1† , Kristi Ajazi 2† , Ayca Sayi-Yazgan3,4, Radmila Jankovic 5 , Biljana Bufan6 , Sven Brandau7 , Espen S. Bækkevold 8 , Florent Petitprez 9 , Malin Lindstedt 2 *, Gosse J. Adema10* and Catarina R. Almeida1 *

Tertiary Lymphoid Structures (TLS) are organized aggregates of immune cells such as T cells, B cells, and Dendritic Cells (DCs), as well as fibroblasts, formed postnatally in response to signals from cytokines and chemokines. Central to the function of TLS are DCs, professional antigen-presenting cells (APCs) that coordinate the adaptive immune response, and which can be classified into different

An Equine Protein Atlas Highlights Synovial Fluid Proteome Dynamics during Experimentally LPS-Induced Arthritis

In human proteomics, substantial efforts are ongoing to leverage large collections of mass spectrometry (MS) fragment ion spectra into extensive spectral libraries (SL) as a resource for data independent acquisition (DIA) analysis. Currently, such initiatives in equine research are still missing. Here we present a large-scale equine SL, comprising 6394 canonical proteins and 89,329 unique peptides

Brexit references in UK financial disclosure discourse (2015-2017) : a corpus study

Major political events become a dominant topic of the discussions in the countries involved, and various actors, often other than political parties, take a stance towards them. The withdrawal of the UK from the European Union as a result of the 2016 UK referendum was one of those, and a quite polarised atmosphere from supporters of both sides was observed in the UK and the rest of Europe since the

Direct Membrane Filtration (DMF) of municipal wastewater – A study on the prevention and remediation of fouling

Direct membrane filtration (DMF) has gained a lot of attention in recent years because of its potential to treat low-strength and low temperature wastewater, where biological based treatments are inefficient. However, fouling is a major concern which keeps this technique from being more widely used. The main aim of this study was to investigate membrane fouling, its mitigation approaches and the o

Inflammatory and cardiovascular markers in placenta following SARS-CoV-2 infection during pregnancy : A Swedish prospective cohort study

INTRODUCTION: Maternal SARS-CoV-2 infection can affect pregnancy outcome, but the placental response to and the effect of timing of infection is not well studied. The aim of this study was to investigate the placental levels of inflammatory and cardiovascular markers in pregnancies complicated by SARS-CoV-2 infection compared to non-infected pregnancies, and to investigate whether there was an ass