Social housing in Ireland has undergone several phases of transformation, including financial restructuring in the 1980s and severe retrenchment during the years of post-crash austerity. Concurrently, the overall housing sector has been defined by several ‘boom and bust’ crisis phases and is currently experiencing a housing crisis characterised by increasingly inflated property and rental prices,

Selective inheritance of sub-cellular components has emerged as a mechanism guiding stem cell fate after asymmetric cell divisions. Peroxisomes play a crucial role in multiple metabolic processes such as fatty acid metabolism and reactive oxygen species detoxification, but the apportioning of peroxisomes during stem cell division remains understudied. Here, we develop a mouse model and labeling te

Stress granules (SGs) are membraneless organelles formed in the cellular cytoplasm under stressful conditions through liquid–liquid phase separation (LLPS). SG assembly can be both dependent and independent of the eIF2α pathway, whereas cellular protein quality control systems mediate SG disassembly. Chaperones and specific domains of RNA-binding proteins strongly contribute to the regulation SG d

Purpose: Abdominal wall complications can be reduced by adhering to guidelines for midline laparotomy closure. However, implementation of guidelines can be challenging. To address this issue, a laparotomy closure device for swift and standardized abdominal closure was developed. The study evaluated the quality of the suture, safety, and speed of the device in a clinical setting. Methods: A prospec

Background: Both aging and Alzheimer's disease (AD) affect brain networks, with early disruptions occurring in regions involved in episodic memory. Few studies have, however, focused on distinguishing region-specific effects of AD-biomarker negative “normal” aging and early amyloid- and tau pathology on functional connectivity. Further, longitudinal studies combining imaging, biomarkers, and cogni

Bladder cancer (BLCA) and diabetes mellitus (DM) are two prevalent diseases that may share molecular mechanisms, suggesting potential links between metabolic disorders and cancer. Using bioinformatics approaches, we integrated multiple databases to identify common genes between BLCA and DM, screening for potential biomarkers. CXCL12 (C-X-C motif chemokine 12, also known as stromal cell-derived fac

Background: Home care underwent abrupt adaptations to handle the COVID-19 pandemic including an accelerated digitalization. While some research exists regarding the working conditions for home care personnel during the COVID-19 pandemic, few studies exist on the effect of everyday technology use in home care during the pandemic. The aim of this study was to investigate how digital technologies, in

Background: Cataracts are the leading cause of reversible blindness globally, disproportionately affecting populations in low- and middle-income countries. In Ethiopia, cataracts remain a significant public health concern. Despite the effectiveness of cataract surgery in restoring vision, information on recovery time and its predictors remain limited. The aim of this study was to assess time to re

The Multipole Injection Kicker (MIK) installed in the 3 GeV ring of MAX IV, is a success story in the use of a non-linear field device ensuring an almost transparent injection into the first ever built fourth-generation storage ring. Reducing the transient stored beam perturbations during top-up injections is particularly relevant for such machines operating at emittances in the regime of few hund

Background: Children aged 0–18 years who need long-term respiratory support rely on medical technology and comprehensive medical care. For this care to be provided at home, access to medical and social support and care is essential. In Sweden, the most notable form is personal care assistance (PCA), which is granted based on legislation and individual authority decisions. We aim to explore the imp

What happens when open, informal spaces disappear – and specifically, what happens when these spaces disappear in a city that used to be full of them? My project is rooted in two things. The first is the highly debated ”Amazon Tower” in Friedrichshain, and the polarized urban conditions around it. The second is my love for Berlin. Berlin has always been a city in flux. However, the latest round

Projektet växte fram ur en önskan att främja en livsstil mer i samklang med livet utomhus. Det resulterade i en undersökande gestaltning kring hur arkitekturen kan bredda begreppet för vad en bostad är – och bör vara – för att främja livskvalitet. Istället för att betrakta bostaden som en plats som tar slut vid ytterväggarna, föreställer jag mig hemmet som en förlängning av den värme och ljus som

Syftet med uppsatsen är att undersöka vilken betydelse commensality, det gemensamma ätandet, har i en svensk kontext. Samt undersöka vilka likheter och skillnader det finns i ätandet mellan unga vuxna, som precis etablerat egna matvanor, och deras föräldrageneration. Arbetet baseras på den problematisering Claude Fischler presenterar som beskriver hur samhällets individualisering även leder till e

Den här uppsatsen börjar i frågeställningen: Hur renoverar man en gård för att få till ett kollektivt liv? Det är ett försök att, med grund i Henri Lefebvres The Production of Space och egna erfarenheter från landsbygden, utforska vad en gård har för unika möjligheter för kollektivt liv. Uppsatsen inleds med en genomgång av landsbygdens problematik och möjliga framtider, genom teori och littera

This essay explores the lived experiences of parents of children with neurodevelopmental disabilities in relation to institutional interactions. Using a narrative inquiry approach (Clandinin & Connelly, 2000), 13 semi-structured interviews were conducted and analysed to investigate emotional and moral dimensions of the participants' stories. Drawing on Kittays (1999) ethic of care, the

Shootings have become the central focus in both the political debate as well as in media coverage. Even though shootings are statistically rare, the symbolic impact they have on public perception is significant. The aim of this thesis is to examine how Swedish media symbolically constructs the public- and parochial realm when shootings occur in them, and what symbolic meanings are attributed to th

In the era of urban renewal in China, historic and ethnic neighborhoods often face the erosion of authentic cultural spaces. Wenhua Lane in Kunming, once a naturally formed multi-ethnic community with strong ties between daily life, space, and cultural practice, has become a typical example of how modernization processes can strip a place of its cultural vitality. Today, Wenhua Lane suffers from a

Diagnosing sepsis in critical care remains a challenge due to the lack of gold-standard diagnostics. Calprotectin (S100A8/A9) has been proposed as a diagnostic marker to identify sepsis in critically ill patients. This study evaluated the diagnostic performance of calprotectin and C-reactive protein (CRP) to distinguish between sepsis and non-sepsis on intensive care unit (ICU) admission. Admissio