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e-Sanctuary: open multi-physics framework for modelling wildfire urban evacuation

The number of evacuees worldwide during wildfire keep rising, year after year. Fire evacuations at the wildland-urban interfaces (WUI) pose a serious challenge to fire and emergency services and are a global issue affecting thousands of communities around the world. But to date, there is a lack of comprehensive tools able to inform, train or aid the evacuation response and the decision making in c

Targeted mass spectrometry for Serum Amyloid A (SAA) isoform profiling in sequential blood samples from experimentally Staphylococcus aureus infected pigs

Serum amyloid A (SAA) is a well-described acute phase protein induced during the acute phase response (APR) to infection. Four isoform specific genes are found in most mammals. Depending on species, SAA3 and SAA4 are ge0nerally preferentially expressed extrahepatically whereas SAA1 and SAA2 are hepatic isoforms dominating the SAA serum pool. Little is known about how specific infections affect the

Explicationist Epistemology and the Explanatory Role of Knowledge

It has been argued that much of contemporary epistemology can be unified under Carnap’s methodology of explication, which originated in the neighboring field of philosophy of science. However, it is unclear to what extent epistemological theories that emphasize the explanatory role of knowledge fit into this picture, Kornblith’s natural kind epistemology and Williamson’s knowledge first approach b

Bridging technique failure through low-tech improvisation: A case study of food microbiology

Modern technology for food safety studies includes standardized protocols and equipment. However, appropriate technology needs to step in to bridge technology dys- or malfunctioning. We examined different low-tech methods for extraction of bacteria from fresh vegetables. Standard equipment including stomacher and filter bags were compared to extraction using bread stick and alternative filter mate

Unified description of structure and reactions : Implementing the nuclear field theory program

The modern theory of the atomic nucleus results from the merging of the liquid drop model of Niels Bohr and Fritz Kalckar, and of the shell model of Marie Goeppert Meyer and Hans Jensen. The first model contributed the concepts of collective excitations. The second, those of independent-particle motion. The unification of these apparently contradictory views in terms of the particle-vibration and

Testing two-nucleon transfer reaction mechanism with elementary modes of excitation in exotic nuclei

Nuclear Field Theory of structure and reactions is confronted with observations made on neutron halo dripline nuclei, resulting in the prediction of a novel (symbiotic) mode of nuclear excitation, and on the observation of the virtual effect of the halo phenomenon in the apparently non-halo nucleus 7Li. This effect is forced to become real by intervening the virtual process with an external (t,p)

Pairing Interaction and Two-Nucleon Transfer Reactions

Soon after the formulation of BCS theory [1], it was recognized by Bohr, Mottelson, and Pines that the existence of an energy gap in the intrinsic excitation spectrum of deformed nuclei displayed a suggestive analogy with that observed in the electronic spectra of metallic superconductors and could, like this one, be described at profit in terms of correlated pairs [2]. Their paper represented the

Investigation of the self activity and high energy γ-rays response of a 1" × 1" and 3" × 3" LaBr3:Ce scintillators

The properties of a cylindrical 1" × 1" and 3" × 3" LaBr3:Ce scintillators (Brillance 380) have been investigated. The first crystal has been analyzed in terms of its self activity due to unstable contaminants emitting a and β particles eventually followed by γ-rays. Coincidence measurements between LaBr3:Ce signals and γ-rays in a HPGe detector were made. The second crystal has been irradiated wi

Quasiparticle renormalization and pairing correlations in spherical superfluid nuclei

Within the framework of nuclear field theory (NFT), the spectrum of atomic nuclei is described in terms of collective and quasiparticle degrees of freedom, that is, of elementary modes of excitation that are directly related to experiment and of their coupling, whose strength and form factors are the basic ingredients entering in the calculations of absolute cross sections of inelastic and of one-

Reaction mechanism of two-neutron transfer in DWBA

We present a brief introduction to the second order DWBA reaction formalism which we have used to perform the theoretical analysis of two-nucleon transfer reactions induced both by heavy and light ions. We also show an example of such a calculation, emphasizing the connection between the structure aspects of the problem and the resulting predicted two-neutron transfer cross section. The calculatio

Two-particle transfer cross sections and nuclear superfluidity

The six measured ASn(p,t)A-2Sn(gs) transfer absolute differential cross sections (A = 112, 116, 118, 120, 122, and 124) are calculated within the framework of DWBA taking into account successive, simultaneous and non-orthogonality contributions, and making use of BCS spectroscopic amplitudes which reproduce the overall distortion of the Fermi distribution around εF . Theory provides an overall acc

Effect of droplet superficial velocity on mixing efficiency in liquid-liquid droplet flow

Enhancement of mixing efficiency in droplets is of great importance to extend the industrial applications of the liquid-liquid twophase flow in micro-scale. In this paper, mixing efficiency in droplets is investigated via the VOF (volume of fluid) method coupledwith UDS (user defined scalar) model. The cross-shaped T junction with a square cross-section is designed and used for dropletformation. D

Influence of volumetric modulated arc therapy and FET-PET scanning on treatment outcomes for glioblastoma patients

Background: We sought to assess the influence of the clinical introduction of new radiotherapy technologies on glioblastoma patients’ outcomes. Methods: Newly diagnosed glioblastoma patients treated with 60 Gy and temozolomide (2005–2014) were analyzed. The patients’ GTV and CTV were defined based on MR (n = 521) or FET-PET/MR (n = 190), and were treated using conformal radiotherapy (CRT, n = 159)

Image-guided radiotherapy reduces the risk of under-dosing high-risk prostate cancer extra-capsular disease and improves biochemical control

Background: To determine if reduced dose delivery uncertainty is associated with daily image-guidance (IG) and Prostate Specific Antigen Relapse Free Survival (PRFS) in intensity-modulated radiotherapy (IMRT) of high-risk prostate cancer (PCa). Methods: Planning data for consecutive PCa patients treated with IMRT (n = 67) and IG-IMRT (n = 35) was retrieved. Using computer simulations of setup erro

Prospective assessment of urinary, gastrointestinal and sexual symptoms before, during and after image-guided volumetric modulated arc therapy for prostate cancer

Objective. The aim of this study was to prospectively assess the development of 24 urinary, gastrointestinal and sexual symptoms in patients with prostate cancer (PCa) during and after image-guided volumetric modulated arc therapy (IG-VMAT). Material and methods. A total of 87 patients with PCa participated in this study. The patients were asked to complete a modified version of the Prostate Cance

Motion management during IMAT treatment of mobile lung tumors - A comparison of MLC tracking and gated delivery

Results: The average gamma index failure rate (2% and 2 mm criteria) was < 0.01% with amplitude gating for all patients, and < 0.1% with phase gating and < 3.7% with MLC tracking for three of the four patients. One of the patients had an average failure rate of 15.1% with phase gating and 18.3% with MLC tracking.With no motion compensation, the average gamma index failure rate ranged from 7.1% to