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A systematic review of the effectiveness of interventions to enhance the healing of chronic ulcers of the foot in diabetes

The outcome of management of diabetic foot ulcers is poor and there is uncertainty concerning optimal approaches to management. We have undertaken a systematic review to identify interventions for which there is evidence of effectiveness. A search was made for reports of the effectiveness of interventions assessed in terms of healing, ulcer area or amputation in controlled clinical studies publish

On the Interior Stress Problem for Elastic Bodies

The classic Sherman-Lauricella integral equation and an integral equation due to Muskhelishvili for the interior stress problem are modified. The modified formulations differ from the classic ones in several respects: Both modifications are based on uniqueness conditions with clear physical interpretations and, more importantly, they do not require the arbitrary placement of a point inside the com

Eye structure correlates with distinct foraging-bout timing in primitive ants

Social insects have evolved remarkable physiological adaptations and behavioural strategies that enable them to access new temporal foraging niches (for example [1]). Here we report striking correlations between the timing of foraging bouts and the modification of eye structure in four species of ants belonging to the primitive genus Myrmecia. Most noteworthy, photoreceptor diameters progressively

Assessment of microvessel density in core needle biopsy specimen in breast cancer

AIM: Estimation of microvessel density (MVD) in primary breast cancer in core needle biopsies (CNB) may predict response to systemic therapy. The aim of the present study was to explore the accuracy of assessment of MVD in CNB related to MVD in excised tumours. MATERIAL AND METHODS: MVD was estimated in core biopsies and subsequently excised tumours in 54 consecutive patients with breast cancer wi

Uncertainties on central exclusive scalar luminosities from the unintegrated gluon distributions.

In a previous report we used the Linked Dipole Chain model unintegrated gluon densities to investigate the uncertainties in the predictions for central exclusive production of scalars at hadron colliders. Here we expand this investigation by also looking at other parameterizations of the unintegrated gluon density, and look in more detail on the behavior of these at small k(). We confirm our concl

A simple score to assess mortality risk in patients waiting for coronary artery bypass grafting

Background. Independent risk factors for death in patients waiting for elective coronary artery bypass surgery have previously been identified. A prioritization where these factors are considered may potentially reduce waiting list mortality. A simple score based on the risk factors was constructed and validated. Methods. A scoring system based on risk factors in 5,864 consecutive patients operate

Shiga toxin-mediated disease in MyD88-deficient mice infected with Escherichia coli O157:H7.

Toll-like receptors (TLRs) are key factors of innate immunity that detect pathogen invasion and trigger a host response. TLR4 can mediate a response through adaptor molecules, MyD88 or TRIF. In the present study, streptomycin-treated MyD88(-/-), Tlr4(-/-), Trif (Lps2/Lps2), and C57BL/6 wild-type (WT) mice were infected with either Shiga toxin (Stx)-producing or non-producing Escherichia coli O157:

Hydrophobic peptide tags as tools in bioseparation

Hydrophobic interactions are highly selective, and differences in surface hydrophobicities between proteins can be used as an efficient handle to facilitate protein isolation. Aromatic amino acid residues are of particular importance for molecular recognition because they have a key role in several biological functions. The hydrophobicity of a protein can easily be altered with minor genetic modif

Acculturation, self-efficacy and social support among Chinese immigrants in Northern Ireland

An opportunity sample of 108 Chinese participants (n(male) = 51 and n(female) = 57; M-age = 29.34) was compared to a second opportunity sample of 98 Northern Irish participants (n(male) = 45 and n(female) = 53; M-age = 23.67) on levels of acculturation, self-efficacy and social support. The administered questionnaire contained three scales to measure the aforementioned constructs. The first was th

Effects of drugs and electrical field stimulation on isolated muscle strips from rabbit pharyngoesophageal segment

Muscle activity of isolated muscle strips from the middle pharyngeal constrictor, the inferior pharyngeal constrictor, the cricopharyngeal muscle, and the cervical esophagus of the rabbit was studied in organ baths in response to drugs and electrical field stimulation. These muscles of the pharyngoesophageal segment seem to lack an autonomic adrenergic and cholinergic innervation, as determined by

Quasi-Deformations of sl2(F) Using Twisted Derivations

In this article we apply a method devised in Hartwig, Larsson, and Silvestrov (2006) and Larsson and Silvestrov (2005a) to the simple 3-dimensional Lie algebra sl2(F). One of the main points of this deformation method is that the deformed algebra comes endowed with a canonical twisted Jacobi identity. We show in the present article that when our deformation scheme is applied to sl2(F) we can, by c

Being different and vulnerable: experiences of immigrant African women who have been circumcised and sought maternity care in Sweden

The purpose of the study was to explore the encounters with the health care system in Sweden of women from Somalia, Eritrea, and Sudan who have been genitally cut. A qualitative study was performed through interviews with 22 women originally from Somalia, Sudan, and Eritrea who were living in Sweden. The women experienced being different and vulnerable, suffering from being abandoned and mutilated

Effects of the pyrethroid insecticide cypermethrin on a freshwater community studied under field conditions. II. Direct and indirect effects on the species composition

The effects of cypermethrin, a commonly used pyrethroid insecticide, were studied in small in situ enclosures situated in an eutrophic lake over an 11-day period. The experimental design used a regression principle that included three untreated controls and a gradient of six unreplicated cypermethrin concentrations, ranging from 0.01 to 6 mug/l. This paper is the second in a series of two and desc

Joint space width of the tibiofemoral and of the patellofemoral joint in chronic knee pain with or without radiographic osteoarthritis: a 2-year follow-up

Objectives: To assess the interval change of the minimal joint space width (MJS) in radiographs of the tibiofemoral (TF) joint and of the patellofemoral (PF) joint with a 2-year follow-up in middle-aged people with longstanding knee pain with or without radiographic osteoarthritis (OA) and to study the precision of the MJS measurements. Design: In the format of a prospective study of early OA the

Expression of the oxytocin gene, but not the vasopressin gene, in the rat uterus during pregnancy: influence of oestradiol and progesterone

Oxytocin (OT) and vasopressin (VP) are neurohypophyseal hormones with potent stimulatory actions on the uterus. In order to determine whether these hormones may have a paracrine action on the uterus, OT and VP gene expression was studied in myometrium from pregnant rats at gestational ages of 14 and 20 days, and from ovariectomized animals treated with oestradiol and progesterone. OT and VP mRNA c

Gas analysis within remote porous targets using LIDAR multi-scatter techniques

Light detection and ranging (LIDAR) experiments are normally pursued for range resolved atmospheric gas measurements or for analysis of solid target surfaces using fluorescence of laser-induced breakdown spectroscopy. In contrast, we now demonstrate the monitoring of free gas enclosed in pores of materials, subject to impinging laser radiation, employing the photons emerging back to the surface la

Application of dummy molecularly imprinted solid-phase extraction in the analysis of cyproheptadine in bovine urine.

Due to the difficulty of monitoring trace levels of cyproheptadine (CYP) residues in complicated biological matrices, specific adsorption materials for the preconcentration and clean-up of CYP are indispensable. In this work, CYP was extracted from urine using dummy molecularly imprinted SPE (DMISPE) to avoid leakage of the imprinting molecules during the desorption phase. For synthesis of DMISPE,

CO2 and O-3 effects on host plant preferences of the forest tent caterpillar (Malacosoma disstria)

Elevated levels of CO2 and O-3 affect plant growth and phytochemistry, which in turn can alter physiological performance of associated herbivores. Little is known, however, about how generalist insect herbivores respond behaviorally to CO2- and O-3-mediated changes in their host plants. This research examined the effects of elevated CO2 and O-3 levels on host plant preferences and consumption of f