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We studied the biomarker patterns related to axonal injury, astrogliosis and amyloid metabolism in cerebrospinal fluid (CSF) of children and adolescents with mitochondrial encephalopathy and identified correlations with phenotype and survival outcome. Forty-six pediatric patients with genetically verified mitochondrial encephalopathy and twenty-two controls investigated at the Queen Silvia Childre

Introduction: The Housing Enabler instrument, designed to measure housing accessibility, has not been used in samples with long-standing spinal cord injury. We aimed to investigate potential threats to the reliability and validity of the instrument when used among older adults with spinal cord injury. Method: Cross-sectional data from the Swedish Aging with Spinal Cord Injury Study (N = 123, injur

The global sensitivity analysis is an effective method to assess the performance of a chemical reaction mechanism. In the present study, the uncertainty analysis and the global sensitivity analysis of a detailed chemical mechanism of n-heptane are first performed based on the Monte Carlo method. The source of the prediction uncertainties of the C0-C7 sub-mechanisms and the reaction classes in the

A popular strategy for meeting over-determination and pre-emption challenges to the comparative counterfactual conception of harm is Derek Parfit’s suggestion, more recently defended by Neil Feit, that a plurality of events harms A if and only if that plurality is the smallest plurality of events such that, if none of them had occurred, A would have been better off. This analysis of ‘harm’ rests o

Due to his ecumenical internationalism, the Swedish Archbishop Nathan Söderblom has been regarded as an opponent of nationalism, contrary to some other Swedish theologians of his time. However, as has been demonstrated by Kjell Blückert, Aila Lauha and others, Söderblom was not without nationalist tendencies. Other scholars have tried to explain his nationalism as mere patriotism. By closely exami

A search is conducted for new resonances decaying into a W or Z boson and a 125 GeV Higgs boson in the νν¯ bb¯ , ℓ±νbb¯ , and ℓ+ℓ−bb¯ final states, where ℓ± = e± or μ±, in pp collisions at s=13 TeV. The data used correspond to a total integrated luminosity of 36.1 fb−1 collected with the ATLAS detector at the Large Hadron Collider during the 2015 and 2016 data-taking periods. The search is conduct

To further improve the flat-type loop heat pipe (LHP) performance, this study evaluates the practical potential of use of highly enhanced boiling structures. It is found that in our proposed new heat pipe (NHP) system, the working fluid from the evaporator outlet to the condenser inlet is in a liquid–vapor two phase flow, which is different from the classical LHP theory. A new P-T diagram is devel

The ignition processes in an ethylene-fueled supersonic combustor excited by laser-induced plasma (LIP) were investigated experimentally under the condition of inflow Ma number of 2.92. The LIP excitation was implemented near the center floor of a flameholding cavity. Optical measurements, including simultaneous CH∗/OH∗ chemiluminescence imaging and Schlieren photography, were used to investigate

Objectives: Successful gestational weight gain (GWG) restriction programs for obese (Body Mass Index (BMI) ≥ 30 kg/m2) pregnant women, have not, so far, shown convincing effects on infant's weight development. An intervention starting during the pregnancy might be too late and a pre-conceptional life style change may be preferable. Thus, the aim of this study was to follow children born to mothers

An asymptomatic Atrial Septal Defect (ASD) is often closed at the age of 3–5 years using a transcatheter or surgical technique. Symptomatic ASD or ASD associated with pulmonary hypertension (PHT) may require earlier closure, particularly in combination with other non-cardiac risk factors for PHT, but the indications for early closure and the potential risk for complications are largely unknown. Th

Purpose Distal radius fracture often compromises working ability, but clinical implications are less studied in men due to its lower incidence. This study therefore describes sick leave in men with distal radius fracture, specifically exploring the impact of patient- and fracture-related factors. Methods Professionally active men aged 20–65 with distal radius fracture were followed prospectively f