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Epigenetic regulation of Cancer Testis Antigens: candidate drivers of genomic instability in Triple Negative Breast Cancer
Cancer Testis (CT) genes are restrictedly expressed in immune-privileged germ tissues and recognised as non-self antigens if aberrantly reactivated in tumours. Beyond their immunotherapeutic potential, certain CT genes have known oncogenic roles, reflecting highly specialised physiological functions in the germline. Meiosis-associated CT genes have been implicated as drivers of genomic instability
A Case Study to develop and test GIS/SDSS methods to assess the production capacity of a Cocoa Site in Trinidad and Tobago
Pritam Kumarsingh A Case Study to develop and test GIS/SDSS methods to assess the production capacity of a Cocoa Site in Trinidad and Tobago Trinidad and Tobago has achieved world-wide affirmation for its unique fine and flavour cocoa (Theobroma cacao). This classification of cocoa commands price premiums on the global market. However, the industry has declined over years. Investors and farmers
Bankernas hållbarhetsrapporter - En studie om hur ansvarstagande redovisas i hållbarhetsrapporter
Formulation development of a recombinant VAR2-antiCD3 protein for cancer immunotherapy
Varje år, varje dag, varje timme, dör någon av cancer. Cancer är den näst dödligaste sjukdomen i världen efter hjärt- och kärlsjukdomar. Dessutom drabbar sjukdomen inte bara de som dör. Många lider fysiskt och psykiskt av sin diagnos och nära och kära utsätts för stor oro för sina närstående. Den bispecifika molekylen rVAR2-aCD3 är ett nytt, lovande läkemedel mot cancer som snart kan börja prövas The use of immunotherapy for treating cancer has received a lot of attention in the recent years. The therapy is based on activating or deactivating the patient’s own immune system to help fight the disease. One way of doing this, is using bispecific molecules that can target both cancer cells and T-cells simultaneously. In 2003, a researcher found that the surface protein VAR2, expressed on mala
Designing a Tool for Improved Decision Documentation in Collaborative Projects
When working in collaborative projects with team members with different expertises, often from different companies, communicative and collaborative challenges that obstructs decision-making can arise due to team members having different objectives. In order to avoid problems and conflicts, good documentation of decision related information is required. The project was performed at Yolean AB, a com
Impact of an interest rate coverage in a life insurance company
A Bayesian Filtering Approach to Incorporate Views in Economic Scenario Generation
Bivariate copula-based regression for modeling results of football matches
Quantification of Fetal Volume in Magnetic Resonance Images Using Deep Learning
Background: Fetal Magnetic Resonance Imaging is an imaging technique that visualizes the fetus during pregnancy. It is used for assessing and diagnosing disease, for monitoring high risk pregnancies, and for conducting research. By segmenting three-dimensional fetal magnetic resonance (MR) images, volume estimation of intrauterine structures is possible. The quantification of fetal body volume and
The Stock market and Human development
Stock market development and its relationship with economic growth has been proven to be significant in previous research but how does it relate to human development? The Human Development Index was first released with the 1990 Human Development Report. If stock market development could impact economic growth could it also impact human development? To analyse the relationship a regression model wa
Design of a rugged intercom system with an interaction design approach
Within a technology-driven company, product usability and interaction design is usually not the main focus. This thesis applies a Human-Centered design process with the aim of creating a more usable and intuitive product. The project is made in collaboration with Axis Communications who aims to expand its portfolio by transferring two intercoms from its subsidiary 2N Telekomunikace to its own asso
Act Local, Think Global. Sustainable Solutions in the Era of Digitalisation
Covid-19-pandemins konsekvenser på svenskt näringsliv - en Space Syntax analys
I december 2019 upptäckte smittskyddsmyndigheten i Kina ett helt nytt virus som senare skulle visa sig spridas och bryta ut till en pandemi över hela världen. Viruset har sedan dess fått namnet SARS-CoV-2 och bidrar till sjukdomen Covid-19. Viruset upptäcktes och identifierades för första gången i staden Wuhan i Hubeiprovinsen, för att sedan spridas till ett stort antal länder över hela världen. DIn December 2019, authorities in China discovered a completely new virus that since then has spread worldwide leading to a pandemic. The virus has since been named SARS-CoV-2 and contributes to infection of Covid-19. The current situation (2021-01-01) of the covid-19-pandemic has affected us all with a rate of 60 million global cases, several unfortunate deaths and a great uncertainty regarding an
Property Tax Mapping and Assessment Using GIS: Case study of Rawalpindi City
PROPERTY TAX MAPPING, ASSESMENT & MONITORING USING GIS Property tax recovery is considered one of the most challenging tasks for governments around the globe in general and in third world countries including Pakistan, India, and Sri Lanka in particular. Today, the existing real property assessment and tax collection system are under pressure to increase its efficiency. Moreover, monitoring anProperty Tax Mapping and Assessment Using GIS Property tax recovery has remained one of the challenging tasks over the years for almost every government around the world, especially in third-world countries. Today, the existing property assessment and tax collection system in Pakistan is antique and defective in many ways and is under pressure to increase its efficiency and tax revenue. Tax asse
”Må Gud välsigna dig med ilskans vrål” - En performativ analys av Sara Parkmans album Vesper
In the last ten years, there has been an ongoing cultural conflict between the nationalist political party the Sweden Democrats (Sverigedemokraterna) and a big group of active Swedish folk musicians. The conflict concerns the definition of ’folk music’ and the question if the genre is to be considered as an inherently more ‘Swedish’ form of cultural expression than other types of music. The Sweden
Bound to Benefit: Exploring How Gender Roles and Relations Shape Women’s Access to Economic Growth from Connectivity: One Case of the Road Corridor in Armenia
The study takes off from gender studies, aiming to identify and explore the relations and roles that people share in society that shape their daily lives. Road corridor investments and how they affect women are argued to be in the middle of a development dilemma where three global agendas that appear incompatible are yet promoted simultaneously. The study aims to explore how gender roles and relat
COOL IT DOWN - Tackling urban heat island effect in Singapore
This master thesis aims to propose sustainable solutions to influence the microclimate, tackle the urban heat island effect and provide a climate-sensitive design for Marina Bay in Singapore. During the site visit and research, the main challenges for Downtown Singapore were identified. The most threatening ones included increasing temperature and the heat island effect. The design principles co
Waring’s Problem and the Hardy-Littlewood circle method
In this bachelor thesis, we appply the Hardy-Littlewood circle method to Waring's problem using Vinogradov's exponential sums approach. On the last section, we focus on the consequeces of the recently proved Vinogradov's mean value theorem.
