Software startups use prototyping to develop and test business ideas and to validate market viability. While prototyping is emphasized in agile methods, there is little research on how startups can best utilise scarce resources to effectively use prototypes in their dynamic business context. We performed a case study of four startups and investigated how startups currently use prototyping to elici

Background: Prototyping is an established practice for user interface design and for requirements engineering within agile software development, even so there is a lack of theory on prototyping. Aims: The main research objective is to provide a means to categorise prototyping instances, in order to enable comparison and reflection of prototyping practices. Method: We have performed a systematic ma

Large-scale software engineering is a collaborative effort where teams need to communicate to develop software products. Managers face the challenge of how to organise work to facilitate necessary communication between teams and individuals. This includes a range of decisions from distributing work over teams located in multiple buildings and sites, through work processes and tools for coordinatin

Nephelometers are regularly used for air quality monitoring through scattering measurements of aerosols in the atmosphere. Less attention has been paid to the potential of estimating soot morphological parameters from nephelometer measurements in combination with scattering theory. In this work, we perform a fundamental laboratory study where an Ecotech Aurora 3000 nephelometer is used for measuri

In a recent article we presented a model for hadronic rescattering, and some results were shown for pp collisions at LHC energies. In order to extend the studies to pA and AA collisions, the Angantyr model for heavy-ion collisions is taken as the starting point. Both these models are implemented within the general-purpose Monte Carlo event generator Pythia, which makes the matching reasonably stra

Objectives: To comprehend the relationship between various indicators of health service equity and patients’ health expenditure poverty in different regions of China, identify areas where equity in health service is lacking and provide ideas for improving patients’ health expenditure poverty. Method: Data from China Family Panel Studies (CFPS) in 2018 and the HFGT index formula were used to calcul

Background: We report the effects of the presentation of an idiopathic subdural hematoma (SDH) in an adult domestic pig on the glymphatic system, a brain-wide solute clearance system. This accidental finding is based on our recently published study that described this system for the first time in large mammals. Our current results define the need to investigate cerebrovascular pathologies that cou

Background: Semi-natural pastures are unfertilized grasslands with a long history of traditional low-input grazing management. This kind of pastures are recognized for their high species richness. However, as a consequence of modernization of agriculture, many of the semi-natural pastures have been lost during the last century, leading to a serious threat to farmland biodiversity. Semi-natural pas

In the past, development of the PYTHIA event generator has mainly concentrated on the physics of proton–proton collisions at high energies, as this is the most important case to modern high energy physics experiments. However, there are situations where more generic beam configurations are relevant. This thesis presents implementations and applications of such processes in PYTHIA. The two applicat

In rural China, marriage-squeezed men are more likely to experience discrimination than other males. Using data collected from Anhui Province in China on marriage-squeezed men’s quality of life, this study examines the influence of discrimination on the quality of life and the buffering effect of social support among this cohort. The results show that discrimination is a strong stressor, and its n

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Breast implant-associated infections (BIAI) occur in approximately 2% of patients after augmentation mammoplasty. In some cases, BIAI can be treated conservatively, whereas others need implant removal. Knowledge of uncommon potential pathogens in BIAI is important to ensure optimal treatment of BIAI. In the present case report, we describe a case of bilateral late Campylobacter jejuni mastitis in

Numerical simulations have been conducted to investigate the effects of pin-fin arrangement and jet Reynolds number on heat transfer enhancement and flow characteristics of a concave confined jet impingement cooled surface conjugated with pin-fins. The results without a pin-fin are used as a baseline. Vortices and different sections of streamlines in the channel are employed to understand the flow

Background: Very preterm infants are at high risk of developing chronic lung disease, which requires respiratory support and might have long-term sequelae. As lung inflammation plays an important role in pathogenesis, antileukotrienes have been explored in both clinical and animal studies. We aimed to assess the benefits and harms of antileukotrienes for the prevention and treatment of respiratory

Active pre-chamber configurations are considered a valuable solution for improving the operation of the internal combustion engine, in the view to overcome the many challenges it has been made to face. Combining this technology with the use of natural gas, a fuel that has increasing availability and interest in the market share, it is possible to burn ultra-lean mixtures (with air-to-fuel ratios,

The European eel population is critically endangered due to a multitude of human-induced factors such as habitat fragmentation, parasites, fishing, and climate change. In freshwater, downstream migrating silver eels encountering hydroelectric plants often suffer substantial delays and increased mortality from trash-rack impingement and turbine-induced mortality. Downstream passage problems can be

Particulate radioactivity, a characteristic of particulate matter, is primarily determined by the abundance of radionuclides that are bound to airborne particulates. Exposure to high levels of particulate radioactivity has been associated with negative health outcomes. However, there are currently no spatially and temporally resolved particulate radioactivity data for exposure assessment purposes.

Background: Despite a far from perfect correlation with middle ear growth, nasopharyngeal cultures are sometimes used in children with acute otitis media (AOM) in order to have some idea of the causative pathogen. How these cultures are used in clinical practice and to what extent they influence clinical management has not previously been studied. The objective with this study was to investigate i