IntroductionAn overview of the different hybrid-processes combining pervaporation with a conventional separation as a tool to recover organic compounds from waste water will be given. Analysing potential applications shows that pervaporation alone will rarely be economical due to the purity required nowadays in waste water treatment. The limitation on flux owing to the activity being the driving f

BACKGROUND: A calcineurin inhibitor (CNI)-free immunosuppressive regimen has been demonstrated to improve renal function early after heart transplantation, but long-term outcome of such a strategy has not been well described. METHODS: In the randomized SCHEDULE trial, de novo heart transplant recipients received (1) everolimus with reduced-exposure CNI (cyclosporine) followed by CNI withdrawal at

Context: Chronic breathlessness is a clinical syndrome that results in significant distress and disability. Morphine can reduce chronic breathlessness when the contributing etiologies are optimally treated. Objectives: Does oxycodone reduce chronic breathlessness compared with placebo? Methods: A multisite, randomized, placebo-controlled, double-blind, parallel-arm, fixed-dose trial of oral contro

The existing information supports the use of this material as described in this safety assessment. Isobutyl alcohol was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization, and environmental safety. Data show that isobutyl alcohol is not genotoxic. Data on isobutyl alcohol provide a calculated M

Eukaryotic elongation factor 1 alpha (eEF1A) delivers aminoacyl-tRNA to the ribosome and thereby plays a key role in protein synthesis. Human eEF1A is subject to extensive post-translational methylation, but several of the responsible enzymes remain unknown. Using a wide range of experimental approaches, we here show that human methyltransferase (MTase)-like protein 13 (METTL13) contains two disti

Valosin-containing protein (VCP, also called p97) is an essential and highly conserved adenosine triphosphate-dependent chaperone implicated in a wide range of cellular processes in eukaryotes, and mild VCP mutations can cause severe neurodegenerative disease. Here we show that mammalian VCP is trimethylated on Lys315 in a variety of cell lines and tissues, and that the previously uncharacterized

This doctoral dissertation comprises three independent essays on information transmission and crisis spillover in the financial markets. The research questions are examined in the context of the foreign exchange market, the stock market and the global banking system.The first paper, The Response of Exchange Rates to Central Bank Communication: A Textual Analysis Approach, investigates how European

According to a popular view, religious fictionalism requires the atheist subject to have independent motivation/justification for all of her religious actions. I challenge this view and argue that all that is needed is a holistic justification of the subject's fictionalist engagement with religion.

Measurements of KS0 and Λ production in tt¯ final states have been performed. They are based on a data sample with integrated luminosity of 4.6 fb - 1 from proton–proton collisions at a centre-of-mass energy of 7 TeV, collected in 2011 with the ATLAS detector at the Large Hadron Collider. Neutral strange particles are separated into three classes, depending on whether they are contained in a jet,

This study exploits policy reforms in Swedish primary care to examine the effect of pay-for-performance (P4P) on compliance with hypertension drug guidelines among public and private health care providers. Using provider-level outcome data for 2005-2013 from the Swedish Prescription Register, providers in regions using P4P were compared to providers in other regions in a difference-in-differences

Control systems can be vulnerable to security threats where an attacker gathers information about the execution of the system. In particular, side-channel attacks exploit the predictability of real-time control systems and of their schedules. To counteract their action, a scheduler can randomize the temporal execution of tasks and limit the amount of information the attacker can gather. Schedule r

High-grade serous ovarian cancer (HGSOC) is the predominant and most lethal histological type of epithelial ovarian cancer. During the last few years, several new treatment options with PARP inhibitors have emerged. The FDA has approved the PARP inhibitor olaparib (Lynparza™) as maintenance treatment after first-line platinum-containing chemotherapy and olaparib, niraparib (Zejula™) and rucaparib

Purpose: To address the systematic bias in whole-brain dual flip angle (DFA) T1-mapping at7T by optimizing the flip angle pair and carefully selecting RF pulse shape and duration.Theory and Methods: Spoiled gradient echoes can be used to estimate whole-brain maps ofT1. This can be accomplished by using only two acquisitions with different flip angles, i.e., aDFA-based approach. Although DFA-based Purpose: To address the systematic bias in whole-brain dual flip angle (DFA) T1-mapping at 7T by optimizing the flip angle pair and carefully selecting RF pulse shape and duration. Theory and Methods: Spoiled gradient echoes can be used to estimate whole-brain maps of T1. This can be accomplished by using only two acquisitions with different flip angles, i.e., a DFA-based approach. Although DFA-ba

BACKGROUND: Although lifestyle factors have been studied in relation to individual non-communicable diseases (NCDs), their association with development of a subsequent NCD, defined as multimorbidity, has been scarcely investigated. The aim of this study was to investigate associations between five lifestyle factors and incident multimorbidity of cancer and cardiometabolic diseases. METHODS: In thi