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Contrasting interests or two sides of the same coin? - tracing economic and social interests in the shaping of EU labour law

The development of EU labour and social law has been described as a pendulum in the sense of focus shifting between economic interests, such as competitiveness for industry, and social interests, such as improving working and living conditions. This view is to a large extent based on the presumption that those interests are contrasting and pursuing one of them would necessarily exclude the promoti

Shared and disease-specific pathways in frontotemporal dementia and Alzheimer’s and Parkinson’s diseases

Neurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and frontotemporal dementia (FTD), exhibit distinct yet overlapping pathological mechanisms. Leveraging large-scale plasma proteomics data from the Global Neurodegeneration Proteomics Consortium, we analyzed 10,527 plasma samples (1,936 AD, 525 PD, 163 FTD, 1,638 dementia and 6,265 controls) to identify di

Inequality in Child Mortality Persists Between Generations in the Netherlands, 1835–1919

In historical the Netherlands, child mortality was distributed unequally between families and this inequality persisted across generations. Using family reconstitution data for the province of Zeeland (LINKS) containing over 200,000 children born 1835–1914, I show that mortality was higher among children under age 5 whose parents lost siblings under age 5. Intergenerational persistence was stronge

Olfactory dysfunction and amyloid-positivity in Parkinson’s disease—longitudinal analysis of cognitive decline and cerebrospinal fluid markers

Background Olfactory dysfunction is a common non-motor symptom in Parkinson’s disease (PD). The objective was to evaluate the association between olfaction in PD with cross-sectional and longitudinal assessments of clinical variables and novel cerebrospinal fluid (CSF) markers. Methods Patients with PD and baseline olfactory function assessed using the Brief Smell Identification Test (B-SIT) were

Sublytic Activity of a Pore-Forming Protein From Commensal Bacteria Causes Epigenetic Modulation of Tumour-Affiliated Protein Expression

Cytolysin A (ClyA) is a pore-forming protein from a strongly silenced gene in non-pathogenic Escherichia coli, including typical commensal isolates in the intestinal microbiome of healthy mammalian hosts. Upon overproduction, ClyA-expressing bacteria display a cytolytic phenotype. However, it remains unclear whether sublytic amounts of native ClyA play a role in commensal E. coli-host interactions

School Meals Case Study: Sweden

This school meals case study forms part of a collection led by the Research Consortium for School Health and Nutrition’s "Good Examples" Community of Practice. The School Meals Case Study of Sweden serves to document how the national school meals programme is organized, funded, and monitored throughout the country. The objectives of this case study include presenting an introduction to the country

Population metagenomics of a symbiont across its ecologically divergent Tephritid fly host ecotypes

Flugan, bakterien och valet mellan tistlarna Mångfalden av liv på jorden formas av samspelet mellan arter och deras miljöer. Ett av de allra äldsta samspelen är det man finner mellan insekter och bakterier, där de ofta lever tillsammans i symbios. I släktet Tephritis (Diptera: Tephritidae, borrflugor) finns just en sådan symbios med bakterien Candidatus Stammerula tephritidis (Stammerula). Genet

Connectivity of three neuron types in the fan-shaped body of the sweat bee: potential substrate for vector memory

Path integration is a navigational strategy that allows animals to return home in a straight line after an outbound journey, by integrating the distance and direction traveled. With their accessible brains, insects are the perfect model organisms to study this target-directed behavior at the neural level. The Central Complex (CX) is a group of neural structures (neuropils) in the insect brain suit

Is release in the wild of an old female that has lived her life in captivity possible? Observations from a lynx breeding centre

The Iberian lynx was once recognized as the world’s most threatened felid, but due to the implementation of a conservation programme and the creation of captive breeding centres, its numbers have considerably increased. With the annual production of new individuals in these reproduction centres, as well as the inevitable aging of past breeders, a different problem emerged: the hoarding of non-repr

What is more acceptable for the farmers? Tendencies and influences in acceptance-opposition of different mitigation measures to prevent wildlife damages among farmers in Hurungwe District, Northern Zimbabwe

The spread of multiuse landscape worldwide has drastically increased humanwildlife interactions and especially negative impacts of wildlife on human assets. Human-wildlife interactions threaten both biodiversity conservation and farmers’ livelihood, especially in low-income areas where farming practices are their main source of income. In Zimbabwe, wildlife damage to crops and livestock creates te

Land-cover change alters stand structure, species diversity, leaf functional traits, and soil conditions in Cambodian tropical forests

Given the severe land-use and land-cover change pressure on tropical forests and the high demand for field observations of ecosystem characteristics, it is crucial to collect such data both in pristine tropical forests and in the converted deforested land-cover classes. To gain insight into the ecosystem characteristics of pristine tropical forests (EFs), regrowth forests (RFs), and cashew plantat

D-amphetamine alters the dynamic ECoG activity distribution patterns in the rat neocortex

Amphetamine has widespread effects on multiple neurotransmitter systems, potentially altering the physiological connectivity and network dynamics across various regions of the brain. In this study, we investigated the effects of D-amphetamine using our previously published approach where electrocorticogram (ECoG) recordings from eight cortical areas provided a coarse estimation of the global activ